• Similarity Matrix of Proteins (SIMAP) is a database of protein similarities created using volunteer computing. It is freely accessible for scientific...
    4 KB (430 words) - 07:52, 18 August 2023
  • nucleotide similarity matrices are much simpler than protein similarity matrices. For example, a simple matrix will assign identical bases a score of +1 and...
    17 KB (2,570 words) - 04:35, 12 July 2024
  • Thumbnail for BLOSUM
    BLOSUM (redirect from Blosum matrix)
    bioinformatics, the BLOSUM (BLOcks SUbstitution Matrix) matrix is a substitution matrix used for sequence alignment of proteins. BLOSUM matrices are used to score...
    22 KB (2,553 words) - 01:31, 17 May 2024
  • Germinal matrix Hair matrix cell Matrix attachment region Matrix metalloproteinase Matrix protein PAM matrix Position-specific scoring matrix Similarity matrix...
    5 KB (629 words) - 12:23, 11 December 2023
  • Thumbnail for Sequence alignment
    alignments of proteins, the degree of similarity between amino acids occupying a particular position in the sequence can be interpreted as a rough measure of how...
    56 KB (6,858 words) - 04:10, 22 June 2024
  • divergent proteins. The probabilities used in the matrix calculation are computed by looking at "blocks" of conserved sequences found in multiple protein alignments...
    15 KB (2,105 words) - 13:47, 21 December 2023
  • Thumbnail for Point accepted mutation
    alignments for proteins. Each entry in a PAM matrix indicates the likelihood of the amino acid of that row being replaced with the amino acid of that column...
    31 KB (4,156 words) - 21:26, 1 April 2024
  • determination of protein structures from NMR or X-ray crystallography. Sometimes it is more convenient to express data as a similarity matrix. It is also...
    31 KB (4,001 words) - 19:37, 5 June 2024
  • A protein superfamily is the largest grouping (clade) of proteins for which common ancestry can be inferred (see homology). Usually this common ancestry...
    24 KB (2,517 words) - 01:44, 29 November 2023
  • Thumbnail for Protein structure prediction
    multiple sequence alignment of a protein family reveals a common level of similarity throughout the lengths of the proteins, PIR refers to the family as...
    73 KB (8,971 words) - 19:55, 21 March 2024
  • database of RNA families IRESbase: A comprehensive database of experimentally validated internal ribosome entry sites. (See also: List of proteins in the...
    37 KB (2,838 words) - 05:08, 26 June 2024
  • family of proteases known as the metzincin superfamily. Collectively, these enzymes are capable of degrading all kinds of extracellular matrix proteins, but...
    23 KB (2,312 words) - 16:09, 10 July 2024
  • Families of Structurally Similar Proteins or FSSP is a database of structurally superimposed proteins generated using the "Distance-matrix ALIgnment"...
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  • Thumbnail for Structural alignment
    valuable tool for the comparison of proteins with low sequence similarity, where evolutionary relationships between proteins cannot be easily detected by...
    44 KB (5,364 words) - 02:05, 27 February 2024
  • Thumbnail for Protein contact map
    Circuit topology Structural classification of proteins CATH HB plot Dot plot (bioinformatics) Self-similarity matrix Pietal, MJ.; Bujnicki, JM.; Kozlowski...
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  • Thumbnail for Cytoskeleton
    Penrose suggest a role of microtubule vibrations in neurons in the origin of consciousness. Accessory proteins including motor proteins regulate and link the...
    45 KB (5,121 words) - 06:34, 27 May 2024
  • Thumbnail for Extracellular matrix protein 2
    protein 2, so named because it shares extensive similarity with known extracellular matrix proteins. GRCh38: Ensembl release 89: ENSG00000106823 – Ensembl...
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  • algorithm is a dynamic programming algorithm. When comparing proteins, one uses a similarity matrix which assigns a score to each possible residue pair. The...
    19 KB (2,483 words) - 14:32, 2 July 2024
  • Thumbnail for Needleman–Wunsch algorithm
    similarity matrix. Here, S(a, b) is the similarity of characters a and b. It uses a linear gap penalty, here called d. For example, if the similarity...
    25 KB (3,235 words) - 19:47, 13 June 2024
  • SIMAP or simap may refer to: Similarity Matrix of Proteins, a database of protein similarities simap.ch, the official gazette for Swiss government procurement...
    203 bytes (55 words) - 09:36, 31 May 2017
  • Thumbnail for Smith–Waterman algorithm
    the similarity measure. The algorithm was first proposed by Temple F. Smith and Michael S. Waterman in 1981. Like the Needleman–Wunsch algorithm, of which...
    36 KB (4,658 words) - 15:11, 11 July 2024
  • amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences. A BLAST search enables a researcher to compare a subject protein or nucleotide...
    38 KB (4,923 words) - 04:36, 8 July 2024
  • Thumbnail for List of volunteer computing projects
    (2011-09-03). "Information on SIMAP". Retrieved 2012-02-05. "SIMAP — Similarity Matrix of Proteins". 2012. Archived from the original on 2012-01-15. Retrieved...
    105 KB (4,255 words) - 20:25, 15 May 2024
  • Thumbnail for Nucleoplasm
    replication, and a variety of metabolic processes. These proteins are divided into histone proteins, a class of proteins that bind to DNA and give chromosomes...
    16 KB (1,925 words) - 22:37, 21 March 2024
  • enzymes represent an ancient family of proteins with major similarities in genetic make-up that are present in a range of diverse organisms from unicellular...
    11 KB (1,632 words) - 21:14, 8 November 2023
  • Thumbnail for Sequence homology
    among DNA, RNA, or proteins is typically inferred from their nucleotide or amino acid sequence similarity. Significant similarity is strong evidence that...
    39 KB (4,179 words) - 23:08, 17 February 2024
  • Thumbnail for Singular value decomposition
    factorization of a real or complex matrix into a rotation, followed by a rescaling followed by another rotation. It generalizes the eigendecomposition of a square...
    86 KB (13,747 words) - 23:03, 11 June 2024
  • including unsupervised approaches such as similarity measures computed on the entity attributes, random walk and matrix factorization based approaches, and...
    19 KB (2,399 words) - 01:51, 30 May 2024
  • Thumbnail for Mitochondrion
    generates ATP in the matrix Specific transport proteins that regulate metabolite passage into and out of the mitochondrial matrix It contains more than...
    165 KB (18,329 words) - 21:48, 15 July 2024
  • of text and a mathematical technique called singular value decomposition (SVD) is used to reduce the number of rows while preserving the similarity structure...
    58 KB (7,634 words) - 18:21, 14 July 2024