Sonidegib (INN), sold under the brand name Odomzo, is a medication used to treat cancer. Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened...
13 KB (1,058 words) - 01:41, 30 August 2024
Administration (FDA) for cancer treatment. These include vismodegib and sonidegib, both inhibitors of Smoothened (SMO), which are being used for the treatment...
27 KB (3,866 words) - 12:49, 22 August 2024
These experimental procedures are not standard care. Vismodegib and sonidegib are drugs approved for specially treating BCC, but are expensive and cannot...
55 KB (5,426 words) - 04:15, 2 November 2024
inhibitors are available for cancer treatment, such as vismodegib and sonidegib. These drugs are regarded as promising cancer therapies, especially for...
59 KB (6,895 words) - 22:30, 25 April 2024
treatment of cancer by inhibiting the hedgehog pathway in a similar way to sonidegib. Itraconazole has a broader spectrum of activity than fluconazole (but...
26 KB (2,397 words) - 16:07, 20 May 2024
Navoban (tropisetron) Chemotherapy-induced nausea and vomiting Odomzo (sonidegib) Locally advanced basal cell carcinoma Ritalin (methylphenidate) ADHD...
144 KB (12,146 words) - 09:25, 31 October 2024
ribociclib -degib hedgehog signaling pathway inhibitors vismodegib, sonidegib -denib IDH1 and IDH2 inhibitors enasidenib, ivosidenib -lisib Phosphatidylinositol...
26 KB (2,150 words) - 12:06, 11 September 2024
Panobinostat L01XH04 Belinostat L01XH05 Entinostat L01XJ01 Vismodegib L01XJ02 Sonidegib L01XJ03 Glasdegib L01XK01 Olaparib L01XK02 Niraparib L01XK03 Rucaparib...
12 KB (877 words) - 15:36, 25 January 2024
inhibitors Everolimus Ridaforolimus Temsirolimus hedgehog inhibitors Glasdegib Sonidegib Vismodegib CDK inhibitors Abemaciclib Dalpiciclib Palbociclib Ribociclib...
12 KB (821 words) - 02:57, 12 October 2024
(14/2011): 10. Li Y, Song Q, Day BW (July 2019). "Phase I and phase II sonidegib and vismodegib clinical trials for the treatment of paediatric and adult...
7 KB (483 words) - 19:42, 20 December 2023
trials Hedgehog pathway inhibitors (e.g. FDA approved vismodegib and sonidegib). Salinomycin has demonstrated potency in killing cancer stem cells in...
20 KB (2,234 words) - 01:21, 22 July 2024
of cyclopamine have been approved by the FDA; vismodegib in 2012, and sonidegib in 2015. Vismodegib was the first Shh pathway drug approved for treating...
16 KB (1,441 words) - 13:23, 1 June 2024
inhibitors Everolimus Ridaforolimus Temsirolimus hedgehog inhibitors Glasdegib Sonidegib Vismodegib CDK inhibitors Abemaciclib Dalpiciclib Palbociclib Ribociclib...
12 KB (758 words) - 23:46, 14 March 2024
being investigated for the treatment of other types of cancer SANT-1 Sonidegib Patidegib Glasdegib Jervine Frizzled GRCh38: Ensembl release 89: ENSG00000128602...
28 KB (3,490 words) - 16:24, 17 March 2024
treatment of cancer by inhibiting the hedgehog pathway in a similar way to Sonidegib. The majority of breast cancers are androgen receptor (AR) positive and...
36 KB (4,350 words) - 18:30, 23 March 2024