• Thumbnail for Squalene
    Squalene is an organic compound. It is a triterpene with the formula C30H50. It is a colourless oil, although impure samples appear yellow. It was originally...
    19 KB (1,793 words) - 16:14, 16 September 2024
  • Thumbnail for Squalene monooxygenase
    Squalene monooxygenase (also called squalene epoxidase) is a eukaryotic enzyme that uses NADPH and diatomic oxygen to oxidize squalene to 2,3-oxidosqualene...
    10 KB (1,146 words) - 01:30, 22 December 2023
  • Thumbnail for Farnesyl-diphosphate farnesyltransferase
    Squalene synthase (SQS) or farnesyl-diphosphate:farnesyl-diphosphate farnesyl transferase is an enzyme localized to the membrane of the endoplasmic reticulum...
    26 KB (3,078 words) - 20:22, 4 September 2024
  • Thumbnail for Steroid
    Lanosterol and cycloartenol are derived from the cyclization of the triterpene squalene. Steroids are named after the steroid cholesterol which was first described...
    84 KB (8,686 words) - 07:48, 29 December 2024
  • Thumbnail for Triterpene
    terpene units. Animals, plants and fungi all produce triterpenes, including squalene, the precursor to all steroids. Triterpenes exist in a great variety of...
    5 KB (509 words) - 14:51, 30 April 2023
  • Squalene methyltransferase (EC 2.1.1.262, TMT-1, TMT-2) is an enzyme with systematic name S-adenosyl-L-methionine:squalene C-methyltransferase. This enzyme...
    2 KB (172 words) - 15:52, 26 August 2023
  • the hydrogenated derivative of squalene, although commercial samples are derived from nature. In contrast to squalene, due to the complete saturation...
    7 KB (539 words) - 16:19, 9 December 2024
  • Botryococcus squalene synthase (EC 1.3.1.96, SSL-2 (gene)) is an enzyme with systematic name squalene:NADP+ oxidoreductase. This enzyme catalyses the following...
    1 KB (117 words) - 13:23, 26 August 2023
  • Squalene—hopanol cyclase (EC 4.2.1.129, squalene—hopene cyclase) is an enzyme with systematic name hopan-22-ol hydro-lyase. This enzyme catalyses the following...
    2 KB (170 words) - 15:52, 26 August 2023
  • Thumbnail for 2009 swine flu pandemic vaccine
    suggested that squalene might be linked to autoimmune disorders. although others suggest squalene might protect people against cancer. Squalene-based adjuvants...
    98 KB (10,211 words) - 03:55, 7 January 2025
  • Thumbnail for Hopanoids
    reacts with squalene in a reaction catalyzed by squalene monooxygenase during sterol biosynthesis. Furthermore, squalene binds to squalene-hopene cyclases...
    42 KB (4,595 words) - 06:35, 10 January 2025
  • Tetrahymanol synthase (EC 4.2.1.123, squalene tetrahymanol cyclase) is an enzyme with systematic name squalene hydro-lyase (tetrahymanol forming). This...
    2 KB (149 words) - 16:00, 26 August 2023
  • Thumbnail for Squalene-hopene cyclase
    Squalene-hopene cyclase (SHC) (EC 5.4.99.17) or hopan-22-ol hydro-lyase is an enzyme in the terpene cyclase/mutase family. It catalyzes the interconversion...
    13 KB (1,430 words) - 15:52, 26 August 2023
  • Thumbnail for Vernix caseosa
    ceramides, cholesterol, fatty acids, triglycerides, waxes and sterol esters, squalene, and phospholipids; multiple detailed analyses of the polar components...
    12 KB (1,336 words) - 13:30, 30 January 2025
  • systematic name squalene mutase (cyclizing, dammara-20,24-diene-forming). This enzyme catalyses the following chemical reaction: squalene ⇌ {\displaystyle...
    1 KB (90 words) - 13:44, 26 August 2023
  • Thumbnail for Terbinafine
    inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that catalyzes the conversion of squalene to lanosterol. In fungi, lanosterol is...
    21 KB (1,830 words) - 14:44, 21 January 2025
  • Thumbnail for Argan oil
    oil also contains traces of tocopherols (vitamin E), phenols, carotenes, squalene. Some trace phenols in argan oil include caffeic acid, oleuropein, vanillic...
    16 KB (1,762 words) - 18:15, 6 December 2024
  • Thumbnail for Kiehl's
    Sharkstewards (2019-12-05). "Squalene and Sharks". Shark Stewards. Retrieved 2024-07-10. Modems, The (2024-04-01). "The Squalene Found in Beauty Products...
    20 KB (1,912 words) - 01:40, 22 January 2025
  • The squalene/phytoene synthase family represents proteins that catalyze the head-to-head condensation of C15 and C20 prenyl units (i.e. farnesyl diphosphate...
    7 KB (785 words) - 17:39, 20 February 2023
  • Thumbnail for Butenafine
    contents to leak out. Furthermore, inhibition of squalene epoxidase leads to a toxic buildup of squalene. This double action of butenafine (increased membrane...
    6 KB (485 words) - 16:52, 15 July 2024
  • E), dolichols, and squalene. Heme A has an isoprenoid tail, and lanosterol, the sterol precursor in animals, is derived from squalene and hence from isoprene...
    18 KB (1,884 words) - 22:51, 1 January 2025
  • led to a few clinical trials. Squalene is a naturally-occurring organic compound used in human and animal vaccines. Squalene is an oil, made up of carbon...
    38 KB (4,233 words) - 17:33, 24 January 2025
  • Thumbnail for Karl Barry Sharpless
    3-oxidosqualene-lanosterol cyclase: featuring enzymic cyclization of modified squalene oxides (Ph.D.). Stanford University. OCLC 66229398. ProQuest 302369766...
    13 KB (1,061 words) - 16:05, 24 December 2024
  • Thumbnail for Siraitia grosvenorii
    revealed five enzyme families involved in the synthesis of mogroside V: squalene epoxidases, triterpenoid synthases, epoxide hydrolases, cytochrome P450s...
    18 KB (1,950 words) - 19:07, 4 January 2025
  • cycloartenol, as well as saponins. It is formed when squalene is oxidized by the enzyme squalene monooxygenase. 2,3-Oxidosqualene is the substrate of...
    3 KB (97 words) - 06:26, 12 July 2024
  • Thumbnail for Terpene
    building blocks. Steroids, for example, are derivatives of the triterpene squalene. Terpenes and terpenoids are also the primary constituents of the essential...
    32 KB (3,491 words) - 12:31, 4 January 2025
  • Thumbnail for Sebaceous gland
    esters (≈26%), squalene (≈12%), and free fatty acids (≈16%). The composition of sebum varies across species. Wax esters and squalene are unique to sebum...
    29 KB (3,377 words) - 09:02, 28 December 2024
  • Thumbnail for Konrad Emil Bloch
    Their work showed that the body first makes squalene from acetate over many steps and then converts the squalene to cholesterol. He traced all the carbon...
    10 KB (884 words) - 22:22, 1 November 2024
  • fungal cell wall synthesis through inhibition of the squalene epoxidase enzyme that converts squalene into ergosterol. Examples of allylamines antifungals...
    28 KB (3,320 words) - 00:51, 3 December 2024
  • Thumbnail for Metabolism
    donors is sterol biosynthesis. Here, the isoprene units are joined to make squalene and then folded up and formed into a set of rings to make lanosterol. Lanosterol...
    113 KB (12,371 words) - 16:51, 16 December 2024