in chemistry, sulfoxidation refers to two distinct reactions. In one meaning, sulfoxidation refers to the reaction of alkanes with a mixture of sulfur...
2 KB (204 words) - 05:24, 19 November 2023
The major routes of metabolism include hydroxylation, N-oxidation, sulfoxidation, demethylation, deamination and conjugation. There is little evidence...
64 KB (5,765 words) - 23:42, 22 December 2024
Bioavailability 100% Protein binding 83% Metabolism Liver via CYP3A4-catalysed sulfoxidation to its active metabolite norquetiapine (N-desalkylquetiapine) Elimination...
79 KB (6,447 words) - 23:29, 8 December 2024
substitution. Alkylsulfonic acids can be prepared by many methods. In sulfoxidation, alkanes are irradiated with a mixture of sulfur dioxide and oxygen...
16 KB (1,935 words) - 16:58, 7 September 2024
bioavailability Protein binding 93% Metabolism Liver glucuronidation and sulfoxidation Elimination half-life 10–19 hours Excretion Kidney and Bile duct Identifiers...
33 KB (2,693 words) - 20:34, 22 December 2024
transcription factor binding profiles. MetOSite: a database about methionine sulfoxidation sites and its functional roles in proteins Healthcare Cost and Utilization...
36 KB (2,839 words) - 07:24, 10 December 2024
typically prepared by oxidation of sulfides, sometimes referred to as sulfoxidation. hydrogen peroxide is a typical oxidant, but periodate has also been...
14 KB (1,425 words) - 15:54, 17 December 2024
PMC 2014938. PMID 10759686. Fargetton X, Galtier P, Delatour P (July 1986). "Sulfoxidation of albendazole by a cytochrome P450-independent monooxygenase from rat...
63 KB (5,186 words) - 04:25, 2 December 2024
benzyl alcohols with high selectivity. Hill et al. have demonstrated the sulfoxidation of thioethers using a MOF based on vanadium-oxo cluster V6O13 building...
178 KB (21,470 words) - 05:02, 28 August 2024
Metabolism Liver, including CYP3A4 and other enzymes (hydrolytic amidation, sulfoxidation, aromatic ring hydroxylation, and glucuronide conjugation) Metabolites...
28 KB (2,363 words) - 00:41, 20 October 2024
O-methylphosphoric ester group can occur which will be followed by methylation and sulfoxidation. This will lead to the formation of methyl sulfinyl-2-ethyl sulfinyl...
18 KB (2,034 words) - 08:42, 23 December 2023
similar strains of Pseudomonas frederiksbergensis in bacterial whole-cell sulfoxidation". Appl Environ Microbiol. 71 (4): 2199–202. doi:10.1128/AEM.71.4.2199-2202...
2 KB (150 words) - 16:51, 5 December 2020
thiolophosphorus bond, an enzymatic S-methylation, desulfuration and sulfoxidation occurred in succession. In rats, the proposed metabolism pathway includes...
16 KB (1,476 words) - 18:06, 27 October 2024
cytochrome P450 activity (see below) possibly as part of demethylation and sulfoxidation detoxification, while less is thought to be due to esterases and glutathione...
33 KB (3,368 words) - 04:28, 31 October 2024
Haehner-Daniels BD, Wrighton SA, Rettie AE, Hall SD (July 2000). "Stereoselective sulfoxidation of sulindac sulfide by flavin-containing monooxygenases. Comparison...
32 KB (3,764 words) - 21:13, 12 August 2023
same levels of enantioselectivity as other protocols, such as Kagan's sulfoxidation system, complexation to a chiral transition metal complex followed by...
13 KB (1,613 words) - 00:28, 5 November 2024
phtalamide ring to the respective phtalamide acid. The process ends with the sulfoxidation, via an FAD-containing monooxygenase, of the sulfur into either sulfoxide...
18 KB (1,967 words) - 22:59, 18 April 2024
reactions including hydroxylations, N,O,S-dealkylations, epoxidations, sulfoxidations, aryl-aryl couplings, ring contractions and expansions, oxidative cyclizations...
13 KB (1,351 words) - 04:07, 27 July 2024
aromatase inhibitor. Methiocarb is biotransformed in the liver mainly by sulfoxidation. This can happen to methiocarb itself but also to the phenol group which...
24 KB (2,886 words) - 00:15, 15 September 2024
by a Porphyrin-Inspired Manganese Complex: Highly Enantioselective Sulfoxidation with a Wide Substrate Scope". Organic Letters. 15 (22): 5658–5661. doi:10...
5 KB (538 words) - 20:01, 24 April 2024
Enzyme 1.14.13.32 at KEGG Fargetton X, Galtier P, Delatour P (1986). "Sulfoxidation of albendazole by a cytochrome P450-independent monooxygenase from rat...
2 KB (199 words) - 13:01, 26 August 2023
arenes to cis-dihydro-diol products. These dioxygenases also catalyze sulfoxidation, desaturation, and benzylic oxidation. These enzymes are prominently...
24 KB (2,879 words) - 17:03, 22 December 2024
The first major route of degradation of carbophenothion in rats is sulfoxidation, as displayed on the right. This product can be further transformed...
19 KB (2,064 words) - 17:55, 7 September 2024
of sulfenito complexes. Metal thioether complexes are susceptible to sulfoxidation with dimethyldioxirane. Being weakly basic, sulfoxide ligands are generally...
7 KB (792 words) - 15:37, 31 January 2024
Bioavailability 55–69% Protein binding >99.9% Metabolism Extensive liver (sulfoxidation); first pass effect Elimination half-life 6.3 hours (mitratapide), up...
4 KB (249 words) - 17:50, 7 September 2024