• Thumbnail for Telomeric repeat-binding factor 2
    throughout the cell cycle. It is also known as TERF2, TRF2, and TRBF2, and is encoded in humans by the TERF2 gene. It is a component of the shelterin nucleoprotein...
    27 KB (3,340 words) - 22:06, 22 December 2023
  • TTAGGG repeat binding factor-1 (TERF1) and TTAGGG repeat binding factor-2 (TERF2). Telomere sequences in humans are composed of TTAGGG sequences which provide...
    13 KB (1,658 words) - 08:34, 4 December 2022
  • specific TF according to literature or domain structure – No motif [930] TERF2 ENSG00000132604 Myb/SANT Inferred motif from similar protein – High-throughput...
    374 KB (81 words) - 02:10, 23 September 2023
  • Thumbnail for G-quadruplex
    regulate hTERT expression In 2019, the telomere-binding-factor-2 (TRF2 or TERF2) was shown to bind to thousands of non-telomeric G-quadruplexes in the human...
    93 KB (11,903 words) - 13:50, 21 August 2024
  • GTPase, binds to dsDNA and prevents HR; and TRF2 protein (also known as TERF2) binds to dsDNA, prevents checkpoint activation through inhibiting ATM recruitment...
    22 KB (2,640 words) - 02:45, 1 December 2023
  • Thumbnail for RTL6
    motif-containing protein BATF3 Basic leucine zipper transcriptional factor ATF-like 3 TERF2 Telomeric repeat-binding factor 2 UXAC Uronate isomerase (Yersinia pestis)...
    20 KB (1,947 words) - 11:18, 21 May 2024
  • Thumbnail for Nibrin
    interact with: Ataxia telangiectasia mutated, BRCA1, H2AFX, MRE11A, Rad50, and TERF2 GRCh38: Ensembl release 89: ENSG00000104320 – Ensembl, May 2017 GRCm38:...
    20 KB (2,609 words) - 04:25, 17 August 2024
  • Thumbnail for Ku70
    CHEK1, CREBBP, GCN5L2, HOXC4, Ku80, MRE11A, NCOA6, NCF4, PCNA, PTTG1, RPA2, TERF2, TERT VAV1, and WRN. GRCh38: Ensembl release 89: ENSG00000196419 – Ensembl...
    15 KB (1,689 words) - 05:45, 11 June 2024
  • Thumbnail for MRE11A
    has been shown to interact with: ATM, BRCA1, Ku70, MDC1, NBN, Rad50, and TERF2. Homologous recombination GRCh38: Ensembl release 89: ENSG00000020922 –...
    19 KB (2,149 words) - 15:10, 21 August 2024
  • participates in telomere maintenance primarily via association with the TERF2 protein of the shelterin complex. Additional studies have suggested that...
    25 KB (3,079 words) - 18:26, 3 December 2023
  • Thumbnail for Rad50
    has been shown to interact with: BRCA1, MRE11A, NBN, RINT1, TERF2IP, and TERF2. Rad50 protein has been mainly studied in eukaryotes. However, recent work...
    19 KB (2,139 words) - 19:03, 25 October 2023
  • Q8NA31 16520 TERB2 HGNC:28520 Q8NHR7 16521 TERF1 HGNC:11728 P54274 16522 TERF2 HGNC:11729 Q15554 16523 TERF2IP HGNC:19246 Q9NYB0 16524 TERT HGNC:11730...
    242 KB (17 words) - 23:17, 27 April 2024
  • Thumbnail for TERF2IP
    TERF2IP has been shown to interact with Ku80, Rad50 and TERF2. Upon interaction, TERF2IP/TERF2 complex has been shown to bind to telomeric junction sites...
    9 KB (1,161 words) - 18:14, 7 August 2022
  • Thumbnail for Werner syndrome helicase
    been shown to interact with: BLM DNA-PKcs, FEN1, Ku70, Ku80, P53, PCNA, TERF2, and WRNIP1. GRCh38: Ensembl release 89: ENSG00000165392 – Ensembl, May...
    30 KB (3,673 words) - 17:08, 27 August 2024
  • Thumbnail for PITRM1
    DEFB104A, HDHD3, MRPL12, NDUFV2, PRDX6, PRKCSH, RARS2, RIF1, SUCLG2, TEKT3, TERF2, and VAPB. GRCh38: Ensembl release 89: ENSG00000107959 – Ensembl, May 2017...
    15 KB (1,668 words) - 20:35, 8 April 2024