Toll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a protein that in humans is encoded by the TLR3 gene. TLR3 is a member of...

TLRs, which activate immune cell responses. The TLRs include TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9, TLR10, TLR11, TLR12, and TLR13. Humans...

viral infections. Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed at the endosomal membrane of B-cells, macrophages and...

damaged RNAs released from UVB-exposed keratinocytes activate TLR3 on intact keratinocytes. TLR3 activation stimulates TNF-alpha and IL-6 production, which...

the original on 14 May 2022. Retrieved 20 October 2021. 14.2: Agonists of TLR3 Myalgic encephalomyelitis/chronic fatigue syndrome at Wikipedia's sister...

PMID 10233312. Liang L, Tan X, Zhou Q, Tian Y, Kijlstra A, Yang P (19 August 2015). "TLR3 and TLR4 But not TLR2 are Involved in Vogt-Koyanagi- Harada Disease by Triggering...

by TLR4 and TLR3 signaling during the innate immune response. Caspase-11, also termed the non-canonical inflammasome, is activated by TLR3/TLR4-TRIF signaling...

receptors RIG-I or MDA5, can trigger release of IFNs. Toll Like Receptor 3 (TLR3) is important for inducing interferons in response to the presence of double-stranded...

include MyD88 deficiency, IRAK-4 deficiency other UNC93B deficiency and TLR3 mutations. Myeloid differentiation primary response gene 88 deficiency (MyD88)...

NGF, BDNF, NT3, NT4/5 Toll-like TLR1 TLR1 " TLR2 TLR2 " Peptidoglycan TLR3 TLR3 " polyIC, polyinosine-polycytosine TLR4 TLR4 " LPS, lipopolysaccharide...

associated with viruses, such as double-stranded RNA (dsRNA), are recognized by TLR3 and unmethylated CpG motifs are recognized by TLR9. The CpG motifs must be...

is a drug which acts as a selective antagonist of Toll-like receptor 3 (TLR3), with an IC50 of 3.44 μM. It is used for research into the function of TRL3...

RIG-I and MDA5) or outside of the cytosol (such as Toll-like receptor 3 (TLR3), TLR7, TLR8 and TLR9) recognise infectious molecules associated with the...

a homozygous UNC93B1 gene; and herpes-specific IIAE2 associated with the TLR3 gene; as well as IIAE4, associated with the CPT2 gene; herpes-specific IIAE5...

double-stranded RNA viruses. Viruses portal Animal virology List of viruses RNA virus TLR3 Virology Virus classification "Double-stranded RNA virus replication". ViralZone...

recognition receptors (PRRs) for exogenous RNA including toll-like receptor 3,7,8 (TLR3, TLR7, TLR8), the RNA helicase RIG1 (RARRES3), protein kinase R (PKR, a.k...

cytokines. The TRIF-dependent pathway is induced by macrophages and DCs after TLR3 and TLR4 stimulation. Molecules released following TLR activation signal...

the cellular surface (TLR1, TLR2, TLR4, TLR5, TLR6) or within endosomes (TLR3, TLR7, TLR8, TLR9) sensing extracellular or phagocytosed pathogens, respectively...

TRIF and TRAF6, and plays an essential role in virus-triggered TLR3-independent and TLR3-mediated antiviral IFN signaling. In 2008 they discovered another...

reduced cell proliferation. TLR3 receptor upregulation was identified in these infected organoids. Inhibition of this TLR3 receptor was shown to partially...

mature and provide immunity to the tumor. Dendritic cell receptors such as TLR3, TLR7, TLR8 or CD40 have been used as antibody targets. Dendritic cell-NK...

2008 Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. doi:10.1038/nature06765 Nature 2009 CCR3 is a target for age-related macular...

viruses are recognized by either the transmembrane toll-like receptor 3 (TLR3) or by one of two cytosolic proteins, retinoic acid-inducible gene I (RIG-I)-like...

protein". Retrieved 2018-03-23. Parsons KS, Hsu AC, Wark PA (January 2014). "TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial...

parasite. . In situ vaccine (ISV), combining Flt3L, local radiotherapy, and a TLR3 agonist (poly-ICLC), could recruit, antigen-load and activate intratumoral...

appropriate signals to the cells of the immune system. CD283 Toll-like receptor 3 (TLR3); abundantly expressed in placenta and pancreas, and restricted to the dendritic...

infections, myelokathexis) EVER1 and EVER2 deficiency Herpes simplex encephalitis TLR3 deficiency TRAF3 deficiency TRIF deficiency TBK1 deficiency IRF3 deficiency...

aspergillosis, such as defects to toll-like receptor (TLR) 4, IL1 and IL15, TLR3, TLR10, TREM1, VEGFA, DENND1B, and PLAT. The full underlying pathogenesis...

and the Trip-dependent pathway. All TLRs except TLR3 signal through the MyD88-dependent pathway. Only TLR3 and TLR4 signal through the TRIF-dependent pathway...

Zhang; Emmanuelle Jouanguy; Sophie Ugolini; et al. (1 September 2007). "TLR3 deficiency in patients with herpes simplex encephalitis". Science. 317 (5844):...