Toll-like receptor 3 (redirect from TLR3)
Toll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a protein that in humans is encoded by the TLR3 gene. TLR3 is a member of...
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Toll-like receptor (section TLR3)
TLRs, which activate immune cell responses. The TLRs include TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9, TLR10, TLR11, TLR12, and TLR13. Humans...
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Polyinosinic:polycytidylic acid (category TLR3 agonist)
viral infections. Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed at the endosomal membrane of B-cells, macrophages and...
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damaged RNAs released from UVB-exposed keratinocytes activate TLR3 on intact keratinocytes. TLR3 activation stimulates TNF-alpha and IL-6 production, which...
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the original on 14 May 2022. Retrieved 20 October 2021. 14.2: Agonists of TLR3 Myalgic encephalomyelitis/chronic fatigue syndrome at Wikipedia's sister...
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PMID 10233312. Liang L, Tan X, Zhou Q, Tian Y, Kijlstra A, Yang P (19 August 2015). "TLR3 and TLR4 But not TLR2 are Involved in Vogt-Koyanagi- Harada Disease by Triggering...
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by TLR4 and TLR3 signaling during the innate immune response. Caspase-11, also termed the non-canonical inflammasome, is activated by TLR3/TLR4-TRIF signaling...
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receptors RIG-I or MDA5, can trigger release of IFNs. Toll Like Receptor 3 (TLR3) is important for inducing interferons in response to the presence of double-stranded...
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include MyD88 deficiency, IRAK-4 deficiency other UNC93B deficiency and TLR3 mutations. Myeloid differentiation primary response gene 88 deficiency (MyD88)...
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NGF, BDNF, NT3, NT4/5 Toll-like TLR1 TLR1 " TLR2 TLR2 " Peptidoglycan TLR3 TLR3 " polyIC, polyinosine-polycytosine TLR4 TLR4 " LPS, lipopolysaccharide...
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associated with viruses, such as double-stranded RNA (dsRNA), are recognized by TLR3 and unmethylated CpG motifs are recognized by TLR9. The CpG motifs must be...
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is a drug which acts as a selective antagonist of Toll-like receptor 3 (TLR3), with an IC50 of 3.44 μM. It is used for research into the function of TRL3...
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RIG-I and MDA5) or outside of the cytosol (such as Toll-like receptor 3 (TLR3), TLR7, TLR8 and TLR9) recognise infectious molecules associated with the...
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a homozygous UNC93B1 gene; and herpes-specific IIAE2 associated with the TLR3 gene; as well as IIAE4, associated with the CPT2 gene; herpes-specific IIAE5...
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double-stranded RNA viruses. Viruses portal Animal virology List of viruses RNA virus TLR3 Virology Virus classification "Double-stranded RNA virus replication". ViralZone...
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recognition receptors (PRRs) for exogenous RNA including toll-like receptor 3,7,8 (TLR3, TLR7, TLR8), the RNA helicase RIG1 (RARRES3), protein kinase R (PKR, a.k...
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cytokines. The TRIF-dependent pathway is induced by macrophages and DCs after TLR3 and TLR4 stimulation. Molecules released following TLR activation signal...
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the cellular surface (TLR1, TLR2, TLR4, TLR5, TLR6) or within endosomes (TLR3, TLR7, TLR8, TLR9) sensing extracellular or phagocytosed pathogens, respectively...
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TRIF and TRAF6, and plays an essential role in virus-triggered TLR3-independent and TLR3-mediated antiviral IFN signaling. In 2008 they discovered another...
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reduced cell proliferation. TLR3 receptor upregulation was identified in these infected organoids. Inhibition of this TLR3 receptor was shown to partially...
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mature and provide immunity to the tumor. Dendritic cell receptors such as TLR3, TLR7, TLR8 or CD40 have been used as antibody targets. Dendritic cell-NK...
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2008 Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. doi:10.1038/nature06765 Nature 2009 CCR3 is a target for age-related macular...
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viruses are recognized by either the transmembrane toll-like receptor 3 (TLR3) or by one of two cytosolic proteins, retinoic acid-inducible gene I (RIG-I)-like...
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protein". Retrieved 2018-03-23. Parsons KS, Hsu AC, Wark PA (January 2014). "TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial...
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parasite. . In situ vaccine (ISV), combining Flt3L, local radiotherapy, and a TLR3 agonist (poly-ICLC), could recruit, antigen-load and activate intratumoral...
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appropriate signals to the cells of the immune system. CD283 Toll-like receptor 3 (TLR3); abundantly expressed in placenta and pancreas, and restricted to the dendritic...
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infections, myelokathexis) EVER1 and EVER2 deficiency Herpes simplex encephalitis TLR3 deficiency TRAF3 deficiency TRIF deficiency TBK1 deficiency IRF3 deficiency...
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aspergillosis, such as defects to toll-like receptor (TLR) 4, IL1 and IL15, TLR3, TLR10, TREM1, VEGFA, DENND1B, and PLAT. The full underlying pathogenesis...
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and the Trip-dependent pathway. All TLRs except TLR3 signal through the MyD88-dependent pathway. Only TLR3 and TLR4 signal through the TRIF-dependent pathway...
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Zhang; Emmanuelle Jouanguy; Sophie Ugolini; et al. (1 September 2007). "TLR3 deficiency in patients with herpes simplex encephalitis". Science. 317 (5844):...
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