TNF receptor-associated factor (TRAF3) is a protein that in humans is encoded by the TRAF3 gene. The protein encoded by this gene is a member of the TNF...

engagement in vivo and the OX40-specific TRAF3 DN defect was partially overcome by CTLA-4 blockade in vivo. TRAF3 may be linked to OX40-mediated memory T...

proteins. Nevertheless, TRAF3 is also involved when the CD40 receptor is activated. When CD40 is stimulated by CD40L, Act1 binds to TRAF3, with the help of...

role of TRAF3 in T cell signalling and function, as well as trying to establish the nuclear roles of TRAF3. T cells that are deficient in TRAF3 have no...

tmTNF, TNFR2 trimerizes and directly recruits TRAF2, as well as TRAF1 or TRAF3. TRAF2 is central to the TNFR2 signaling complex, and recruits cIAP1/2....

seven TRAF proteins have been characterized in mammals: TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6 and TRAF7. Except for TRAF7, these proteins share a...

TRAF3-interacting JNK-activating modulator is a protein that in humans is encoded by the TRAF3IP3 gene. TRAF3IP3 has been shown to interact with STRN...

cell haematopoiesis. CD40 (protein) has been shown to interact with TRAF2, TRAF3, TRAF6, TRAF5 and TTRAP. The remaining member of TRAF4 family, namely TRAF4...

lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2, TRAF3, and TRAF5 have been shown to mediate the signaling process of this receptor...

associated with the CPT2 gene; herpes-specific IIAE5 associated with the TRAF3 gene; herpes-specific IIAE6 associated with the TICAM1 gene; herpes-specific...

maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated...

been shown to interact with: CASP8 NMT2 CFLAR DCC GroEL HCLS1 Survivin TRAF3 XIAP NFE2L2 Caspase-3 has been found to be necessary for normal brain development...

RNF215, RNFT1, SH3MD4, SH3RF1, SH3RF2, SYVN1, TIF1, TMEM118, TOPORS, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6, TRAF7, TRAIP, TRIM2, TRIM3, TRIM4, TRIM5, TRIM6, TRIM7...

by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent...

smoking-related cancers: HPV-positive characterized by shortened or deleted TRAF3, HPV-negative characterized by co-amplification of 11q13 and 11q22, smoking-related...

thus aka HVEML. Also interacts with decoy receptor 3, BIRC2, TRAF2 and TRAF3. CD259 not assigned CD260 not assigned CD261 Death receptor 4 (DR4), TRAIL...

"Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif". The EMBO Journal. 25 (14): 3257–3263. doi:10.1038/sj.emboj...

EVER1 and EVER2 deficiency Herpes simplex encephalitis TLR3 deficiency TRAF3 deficiency TRIF deficiency TBK1 deficiency IRF3 deficiency CARD9 deficiency...

Zachariah S, Quiñones HI, Shindo M, Chaudhary PM (November 2002). "Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked...

disease. Nucleoporin 62 has been shown to interact with: HSF2, KPNB1, NUTF2, TRAF3, and XPO1, Nup93. GRCh38: Ensembl release 89: ENSG00000213024 – Ensembl...

Adaptor Molecule (TRAM). TRAM-TRIF signals activate the ubiquitin ligase TRAF3 followed by the activation of non-canonical IKK kinases: TANK binding kinase...

of the PTPN22 is TRAF3. This protein bind the PTPN22 and regulate its translocalization to a plasma membrane, in the absence of TRAF3 there is  a bigger...

components in virus-induced activation of NF-κB and/or IRF3, including TRAF3, TRAF6, TANK, NEMO (IKKg), TRADD, FADD, and RIP (Kawai et al., 2005; Michallet...

LIGHT has been shown to interact with TNFRSF14, TNFRSF6B, BIRC2, TRAF2 and TRAF3. Similar to how CD4 is the primary mediating receptor in HIV infection,...

Q15628 17288 TRAF1 HGNC:12031 Q13077 17289 TRAF2 HGNC:12032 Q12933 17290 TRAF3 HGNC:12033 Q13114 17291 TRAF3IP1 HGNC:17861 Q8TDR0 17292 TRAF3IP2 HGNC:1343...

doi:10.1073/pnas.160265197. PMC 27051. PMID 10962024. "Entrez Gene: TRAF3IP2 TRAF3 interacting protein 2". Qian Y, Qin J, Cui G, Naramura M, Snow EC, Ware...

Sinha SK, Zachariah S, Quiñones HI, Shindo M, Chaudhary PM (2003). "Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked...

modules to TRAFs and scaffolding. D. Degradation of canonical Ubiquitin-TRAF3 by the proteasome, release of non-canonical Ubiquitin-TRAF2 and -MAP3Ks...

Wooters J, Qiu Y, Wang J, Lin LL (2003). "Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism...

Lymphotoxin beta receptor has been shown to interact with Diablo homolog and TRAF3. GRCh38: Ensembl release 89: ENSG00000111321 – Ensembl, May 2017 GRCm38:...