2018.10.007. PMC 6299210. PMID 30503508. Sebastian S, Luban J (2005). "TRIM5alpha selectively binds a restriction-sensitive retroviral capsid". Retrovirology...
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Uncoating inhibitors TRIM5alpha (gene) Transcription inhibitors Tat antagonists Translation inhibitors Trichosanthin BNAbs Elipovimab Other Abzyme BIT225†...
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Uncoating inhibitors TRIM5alpha (gene) Transcription inhibitors Tat antagonists Translation inhibitors Trichosanthin BNAbs Elipovimab Other Abzyme BIT225†...
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factors—for example, with respect to retroviruses, relevant genes include TRIM5alpha, APOBEC, and Tetherin, representing directly antiviral effects Primes...
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effects. Other proteins that function to restrict HIV replication include TRIM5alpha and APOBEC3G. It has been demonstrated that treatment of cells with interferon...
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Emerman M (2007). "Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein". Science. 316 (5832): 1756–8. Bibcode:2007Sci...316...
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has been shown to interact with: ITK, CD147, P53, STAT3, Cyclophilin TRIM5alpha GRCh38: Ensembl release 89: ENSG00000196262 – Ensembl, May 2017 "Human...
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investigations of host restriction factors such as Fv1,[citation needed] TRIM5alpha and other members of the tripartite motif family as well as the lentiviral...
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Uncoating inhibitors TRIM5alpha (gene) Transcription inhibitors Tat antagonists Translation inhibitors Trichosanthin BNAbs Elipovimab Other Abzyme BIT225†...
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motif-containing 6". Li X, Gold B, O'hUigin C, et al. (2007). "Unique features of TRIM5alpha among closely related human TRIM family members". Virology. 360 (2): 419–33...
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TNFRSF21 TNFRSF25 Tolerance to infections Toxoid TPBG Transfer factor TRIF TRIM5alpha Trogocytosis Tuberculin Tumor necrosis factor alpha Tumor necrosis factor...
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"Hsp70 interacts with the retroviral restriction factor TRIM5alpha and assists the folding of TRIM5alpha". The Journal of Biological Chemistry. 285 (10): 7827–7837...
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Autissier P, Sodroski J (February 2004). "The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys". Nature. 427 (6977): 848–53...
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PMID 16189514. S2CID 4427026. Yap MW, Nisole S, Lynch C, Stoye JP (July 2004). "Trim5alpha protein restricts both HIV-1 and murine leukemia virus". Proceedings of...
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either activating or inhibiting its target protein function. For example, TRIM5alpha restriction of retroviral reverse-transcription is dependent on UBE2V2/UBE2N-mediated...
13 KB (1,677 words) - 01:28, 9 April 2022