TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia. TRPM Ruthenium red GRCh38: Ensembl release...
2 KB (281 words) - 20:54, 20 June 2023
occurs by membrane transport through the TRPM6 ion channels and is crucial for magnesium homeostasis. TRPM6 is expressed on the part of the cell membrane...
12 KB (1,033 words) - 04:04, 6 January 2024
Magnesium transporter (section TRPM6/ TRPM7)
homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been...
93 KB (12,023 words) - 08:10, 10 June 2024
hypomagnesemia, Other genetic causes of hypomagnesemia, such as mutations in TRPM6, CNNM2, EGF, EGFR, KCNA1 or FAM111A. Many of the proteins encoded by these...
44 KB (4,489 words) - 18:20, 17 August 2024
motifs but, rather, contain entire functional proteins in their C-termini. TRPM6 and TRPM7, for example, contain functional α-kinase segments, which are...
7 KB (821 words) - 22:40, 16 July 2024
Na+/K+-ATPase. Indicated also are the recently identified magnesium channel TRPM6 in the apical membrane, and a putative Na/Mg exchanger in the basolateral...
28 KB (2,941 words) - 22:23, 13 August 2024
These include mammalian ion channels (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, mCa1, mCa2, CALHM1)...
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Konrad M, Gudermann T (2004). "Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia"...
86 KB (10,448 words) - 22:13, 6 August 2024
and βTRPM. αTRPMs include vertebrate TRPM1, TRPM3, and the "chanzymes" TRPM6 and TRPM7, as well as the only insect TRPM channel, among others. βTRPMs...
49 KB (5,517 words) - 22:16, 16 July 2024
kinases that include elongation factor-2 kinase (eEF2K) and channel-kinases TRPM6 and TRPM7. Ryazanov and his colleagues demonstrated that eEF2K is a regulator...
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Q9HCF6 17472 TRPM4 HGNC:17993 Q8TD43 17473 TRPM5 HGNC:14323 Q9NZQ8 17474 TRPM6 HGNC:17995 Q9BX84 17475 TRPM7 HGNC:17994 Q96QT4 17476 TRPM8 HGNC:17961 Q7Z2W7...
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TRPC1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7 TRPM1; TRPM2; TRPM3; TRPM4; TRPM5; TRPM6; TRPM7; TRPM8 TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6 MCOLN1; MCOLN2; MCOLN3;...
19 KB (1,692 words) - 03:53, 29 November 2023
TRPC2 TRPC3 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML TRPN TRPP TRPP3 TRPV TRPV1 TRPV2 TRPV3 TRPV4 TRPV5 TRPV6...
15 KB (1,545 words) - 18:32, 17 August 2024
Barbara; Beck, Gretel E.; Englehardt, Richard K. (1 June 2002). "Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia". Nature Genetics...
25 KB (2,526 words) - 13:58, 14 August 2024
S2CID 16274084. Chubanov V, Gudermann T, Schlingmann KP (2005). "Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis". Pflügers...
4 KB (545 words) - 03:41, 12 August 2024
renal; 611718; EGF Hypomagnesemia with secondary hypocalcemia; 602014; TRPM6 Hypomagnesemia, primary; 248250; CLDN16 Hypomagnesemia, renal, with ocular...
234 KB (18,877 words) - 15:43, 9 May 2024