Topotecan, sold under the brand name Hycamtin among others, is a chemotherapeutic agent medication that is a topoisomerase inhibitor. It is a synthetic...
17 KB (1,503 words) - 00:15, 27 August 2024
until 1996 – after further research and rounds of clinical trials – that topotecan, a synthetic derivative of a chemical in the plant, was approved for use...
8 KB (755 words) - 03:14, 20 July 2024
Vorinostat Zabadinostat Belotecan Camptothecin Exatecan Gimatecan Irinotecan Topotecan Etoposide Teniposide Tafluposide Bortezomib Erlotinib Gefitinib Imatinib...
5 KB (324 words) - 12:07, 20 July 2024
investigation for or used as drugs for cancer treatment, including irinotecan, topotecan, rubitecan. C. acuminata also contains the chemical compounds trifolin...
2 KB (192 words) - 22:31, 28 April 2024
analogues have been approved and are used in cancer chemotherapy today: topotecan, irinotecan, belotecan, and trastuzumab deruxtecan. Camptothecin has also...
25 KB (2,510 words) - 13:39, 29 May 2024
relapsed ovarian cancer, evidence suggests topotecan has a similar effect on overall survival as paclitaxel and topotecan plus thalidomide, whilst it is superior...
198 KB (21,176 words) - 22:22, 15 September 2024
include, but is not limited to, confusion and memory loss. The use of topotecan has been investigated. There are several new[when?] clinical trials in...
11 KB (1,003 words) - 18:12, 26 July 2024
Paclitaxel, Irinotecan, Oxaliplatin, Gemcitabine, Cytarabine, Carboplatin, Topotecan, Docetaxel, and Epirubicin. Fresenius Vamed develops and manages health...
19 KB (1,666 words) - 12:24, 14 September 2024
order to make artificial liposomes loaded with anti-cancer drugs such as Topotecan. In IVF field, Ca Ionophore can be used in case of low fertilization rate...
7 KB (559 words) - 20:39, 22 November 2023
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
61 KB (6,082 words) - 05:23, 17 June 2024
both of these processes. Two topoisomerase I inhibitors, irinotecan and topotecan, are semi-synthetically derived from camptothecin, which is obtained from...
155 KB (17,546 words) - 16:49, 16 August 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
31 KB (2,908 words) - 03:40, 16 September 2024
Vincristine, Actinomycin, and Cyclophosphamide Alternating With Vincristine, Topotecan, and Cyclophosphamide for Intermediate-Risk Rhabdomyosarcoma: Children's...
20 KB (1,865 words) - 04:30, 3 January 2024
chemotherapy-resistant disease. Those who relapse are given second-line chemotherapies. Topotecan and lurbinectedin are approved by the US FDA for this purpose. Irinotecan...
90 KB (9,784 words) - 14:55, 21 June 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
36 KB (3,299 words) - 19:46, 10 August 2024
This possibility has been demonstrated by a recent study where the drug topotecan, administered to mice suffering from AS, activated expression of the paternal...
23 KB (2,858 words) - 11:13, 28 March 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
4 KB (411 words) - 21:05, 6 May 2024
megestrol, mitomycin, mitoxantrone, paclitaxel, procarbazine, tamoxifen, topotecan Some antidepressants like imipramine, phenelzine, trazodone Some antipsychotics...
64 KB (6,621 words) - 21:00, 29 August 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
60 KB (6,439 words) - 04:38, 7 September 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
9 KB (595 words) - 19:48, 16 June 2024
TIZANIDINE 503. TABRAMYCIN 504. TOLFENAMIC ACID 505. TOPIRAMATE 506. TOPOTECAN HYDROCHLORIDE 507. TRAMADOL HYDROCHLORIDE 508. TRANEXAMIC ACID 509. TRANYLCYPROMINE...
16 KB (253 words) - 16:47, 23 February 2023
potential use as treatments for cancer and HIV. The modern chemotherapy drugs topotecan and irinotecan are derived from it, though now the molecules are produced...
4 KB (362 words) - 06:47, 16 September 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
15 KB (1,438 words) - 02:57, 10 May 2024
Song IC, Ko YB, Lee HJ (April 2018). "The combination of cisplatin and topotecan as a second-line treatment for patients with advanced/recurrent uterine...
109 KB (11,310 words) - 02:20, 4 September 2024
2019). "ATLANTIS: a Phase III study of lurbinectedin/doxorubicin versus topotecan or cyclophosphamide/doxorubicin/vincristine in patients with small-cell...
20 KB (1,473 words) - 07:20, 19 September 2023
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
11 KB (729 words) - 05:53, 22 August 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
31 KB (2,821 words) - 10:12, 17 July 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
26 KB (2,640 words) - 19:37, 25 August 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
20 KB (1,809 words) - 14:07, 16 September 2024
pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide# Teniposide) II+Intercalation Anthracyclines...
14 KB (1,105 words) - 06:03, 14 September 2024