Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene. TfR1...
8 KB (937 words) - 08:12, 4 October 2023
Transferrin receptor (TfR) is a carrier protein for transferrin. It is needed for the import of iron into cells and is regulated in response to intracellular...
9 KB (1,014 words) - 02:23, 28 October 2023
transferrin receptors found in humans denoted as transferrin receptor 1 (TfR1) and transferrin receptor 2 (TfR2). Although both are similar in structure...
24 KB (2,777 words) - 16:03, 10 July 2024
transferrin receptor conventionally refers to the cleaved extracellular portion of transferrin receptor 1 that is released into serum. This receptor is...
3 KB (375 words) - 19:56, 13 August 2023
although its role is minor compared to transferrin receptor 1. This gene is a member of the transferrin receptor-like family and encodes a single-pass...
8 KB (952 words) - 15:36, 4 January 2024
take up iron primarily through receptor-mediated endocytosis via transferrin receptor 1 (TFR1), transferrin receptor 2 (TFR2) and GAPDH. TFR1 has a 30-fold...
46 KB (5,567 words) - 18:09, 20 August 2024
a type of iron overload disorder associated with deficiencies in transferrin receptor 2. It exhibits an autosomal recessive inheritance pattern. The first...
17 KB (1,854 words) - 04:32, 27 September 2023
Lassa mammarenavirus (section Receptors)
Sabia in addition to the non pathogenic Amapari virus, use the transferrin receptor 1. A small aliphatic amino acid at the GP1 glycoprotein amino acid...
21 KB (2,461 words) - 18:07, 27 February 2024
co-develop/commercialize at least one of CytomX Probody's conjugates against CD71 (transferrin receptor 1). In March 2020, AbbVie announced plans to evaluate the Kaletra/Aluvia...
40 KB (3,359 words) - 06:40, 2 August 2024
(vesicles up to 1 μm in diameter with connected tubules of approx. 50 nm diameter). Markers include RAB5A and RAB4, Transferrin and its receptor and EEA1. Late...
22 KB (2,647 words) - 07:14, 29 May 2024
potential target to attenuate immune rejection. Antibodies CD71/Transferrin receptor-1 CD13 marker for kidney disorder CD33 marker for AML treatment CD4+/CD8+...
14 KB (1,368 words) - 18:49, 18 August 2024
bound transferrin, owing to changes in the UV-Vis spectrum. The formation constant for Cr3+ in the C-lobe is 1.41 x 1010 M−1 and 2.04 x 105 M−1 in the...
46 KB (5,094 words) - 19:52, 15 August 2024
by the cell (examples include LDL via the LDL receptor or iron via transferrin). The role of receptor-mediated endocytosis is well recognized up take...
10 KB (1,096 words) - 11:02, 3 December 2023
circulating iron uptake by regulating the interaction of the transferrin receptor with transferrin. The HFE gene contains 7 exons spanning 12 kb. The full-length...
20 KB (2,300 words) - 18:39, 10 March 2024
Iron-responsive element-binding protein (category EC 4.2.1)
transferrin receptor mRNA. The transferrin receptor mRNA is rapidly degraded without the IRE-BP attached to it. The cell stops producing transferrin receptors...
8 KB (997 words) - 02:27, 18 October 2022
Ferroportin (redirect from Ferroportin 1)
hemochromatosis: transferrin receptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (IRP)-1 and -2, and hepcidin"...
21 KB (2,439 words) - 01:30, 28 March 2024
take up iron primarily through receptor-mediated endocytosis via transferrin receptor 1 (TFR1), transferrin receptor 2 (TFR2) and GAPDH. TFR1 has a 30-fold...
44 KB (5,376 words) - 09:18, 1 July 2024
Pearson, Richard D.; Rangel, Gabriel (2018-01-05). "Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax". Science. 359 (6371): 48–55...
12 KB (1,221 words) - 02:23, 27 July 2024
active against all tested mammarenaviruses that use the transferrin receptor 1 as their receptor was under investigation in 2020. Radoshitzky, SR; Buchmeier...
37 KB (4,048 words) - 19:02, 30 July 2024
recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors". The Journal of Biological Chemistry...
33 KB (3,380 words) - 19:17, 10 July 2024
ferroportin. Ferroportin Q248H also unregulated the expression of transferrin receptor-1 in the same way as wild type. This indicates the ferroportin Q248H...
21 KB (2,165 words) - 00:46, 18 June 2024
the BBB via transport on brain endothelial receptors such as the insulin receptor or transferrin receptor. The transporter protein acts as a molecular...
20 KB (2,229 words) - 07:06, 1 December 2023
Theoretically, a decrease in transferrin could additionally be decreased by an upregulation of transferrin receptors, but the latter does not appear...
11 KB (1,096 words) - 14:00, 24 December 2023
transcripts that encode iron metabolism genes, including ferritin, transferrin receptor 1, ferroportin, HIF2 alpha, and several other transcripts. IRP1 acquires...
6 KB (620 words) - 05:12, 6 April 2024
that have different receptors responsible for the receptor-mediated endocytosis of ligands, e.g. low density lipoprotein, transferrin, growth factors, antibodies...
25 KB (2,980 words) - 14:58, 19 June 2024
Interleukin 4 (redirect from Receptors, interleukin-4)
overexpress receptors for various growth factors including epidermal growth factor receptor, FGFR-1 (fibroblast growth factor receptor 1), TfR (transferrin receptor)...
19 KB (2,293 words) - 11:05, 8 March 2024
Lactoferrin (category Transferrins)
known as lactotransferrin (LTF), is a multifunctional protein of the transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass...
49 KB (5,709 words) - 03:20, 24 June 2024
Punnonen, K; Rajamäki, A; Irjala, K (October 1998). "Serum transferrin receptor and transferrin receptor-ferritin index identify healthy subjects with subclinical...
13 KB (1,432 words) - 08:59, 13 August 2023
cells of pancreatic islets leads to diabetes due to distribution of transferrin receptor on the beta cells of islets and in the skin leads to hyperpigmentation...
12 KB (1,299 words) - 18:42, 2 April 2024
mutations in genes coding for the iron regulatory proteins hemojuvelin, transferrin receptor-2 and ferroportin. Hereditary hemochromatosis is characterized by...
46 KB (4,693 words) - 09:51, 14 August 2024