• Thumbnail for Trastuzumab
    Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. It is specifically...
    67 KB (5,895 words) - 12:08, 7 May 2024
  • Thumbnail for Trastuzumab deruxtecan
    Trastuzumab deruxtecan, sold under the brand name Enhertu, is an antibody-drug conjugate consisting of the humanized monoclonal antibody trastuzumab (Herceptin)...
    25 KB (2,085 words) - 03:15, 6 July 2024
  • Thumbnail for Trastuzumab emtansine
    Trastuzumab emtansine, sold under the brand name Kadcyla, is an antibody-drug conjugate consisting of the humanized monoclonal antibody trastuzumab (Herceptin)...
    29 KB (2,699 words) - 00:43, 10 February 2024
  • Pertuzumab/trastuzumab/hyaluronidase, sold under the brand name Phesgo, is a fixed-dose combination medication to treat adults with HER2-positive breast...
    12 KB (966 words) - 04:46, 15 July 2024
  • Thumbnail for HER2
    antibody trastuzumab (marketed as Herceptin). Trastuzumab is effective only in cancers where HER2 is over-expressed. One year of trastuzumab therapy is...
    43 KB (4,651 words) - 05:18, 13 July 2024
  • Trastuzumab/hyaluronidase, sold under the brand name Herceptin SC among others, is a fixed-dose combination medication for the treatment of HER2-overexpressing...
    11 KB (703 words) - 18:13, 27 March 2024
  • Thumbnail for Pertuzumab
    brand name Perjeta, is a monoclonal antibody used in combination with trastuzumab and docetaxel for the treatment of metastatic HER2-positive breast cancer;...
    24 KB (2,275 words) - 00:45, 12 July 2024
  • Thumbnail for Antibody–drug conjugate
    authorization from the European Medicines Agency in October 2012. Trastuzumab emtansine (ado-trastuzumab emtansine or T-DM1, trade name: Kadcyla, marketed by Genentech...
    40 KB (4,270 words) - 13:46, 14 July 2024
  • Thumbnail for Tucatinib
    2021. Tucatinib is a kinase inhibitor indicated in combination with trastuzumab and capecitabine for the treatment of adults with advanced unresectable...
    21 KB (1,683 words) - 18:47, 17 March 2024
  • Thumbnail for Exatecan
    of camptothecin with antineoplastic activity. A derivative is used in Trastuzumab deruxtecan. Abou-Alfa, GK; Letourneau, R; Harker, G; Modiano, M; Hurwitz...
    3 KB (98 words) - 05:18, 1 January 2024
  • aspart, insulin glargine, pegfilgrastim, rituximab, teriparatide, and trastuzumab. A research article about "Maximizing the benefits of using biosimilars...
    95 KB (6,480 words) - 22:51, 13 May 2024
  • Thumbnail for Hyaluronidase
    (Rituxan Hycela), trastuzumab/hyaluronidase-oysk (Herceptin Hylecta), daratumumab/hyaluronidase-fihj (Darzalex Faspro), and pertuzumab/trastuzumab/hyaluronidase–zzxf...
    31 KB (2,895 words) - 10:05, 2 June 2024
  • Thumbnail for Uterine serous carcinoma
    antibody trastuzumab (Herceptin) is currently being tested as a therapy for this subset of uterine serous carcinomas. The antibody trastuzumab (Herceptin)...
    10 KB (1,197 words) - 17:13, 13 June 2024
  • Thumbnail for Mertansine
    create an antibody-drug conjugate (ADC). ADCs with this design include trastuzumab emtansine, lorvotuzumab mertansine, and cantuzumab mertansine. Some are...
    6 KB (471 words) - 09:43, 12 February 2024
  • Thumbnail for Breast cancer
    HER2-targeted antibody trastuzumab to chemotherapy reduces the chance of cancer recurrence and death by at least a third. Trastuzumab is given weekly or every...
    129 KB (14,628 words) - 14:31, 8 July 2024
  • Thumbnail for Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
    example, a targeted anticancer agent – trastuzumab emtansine (antibody-drug conjugate containing an antibody trastuzumab chemically linked to a highly potent...
    2 KB (97 words) - 22:42, 6 February 2024
  • Kadcyla (ado-trastuzumab emtansine): The first Genentech antibody-drug conjugate (ADC) to receive FDA approval. It consists of trastuzumab (Herceptin)...
    38 KB (3,369 words) - 17:52, 24 May 2024
  • Isatuximab L01FD01 Trastuzumab L01FD02 Pertuzumab L01FD03 Trastuzumab emtansine L01FD04 Trastuzumab deruxtecan L01FD05 Trastuzumab duocarmazine L01FD06...
    12 KB (877 words) - 15:36, 25 January 2024
  • Thumbnail for Oncology
    antibody treatments, notably for lymphoma (Rituximab) and breast cancer (Trastuzumab). Vaccines and other immunotherapies are the subject of intensive research...
    24 KB (2,589 words) - 20:56, 22 May 2024
  • Thumbnail for Doxorubicin
    other cardiotoxic chemotherapy drugs, such as trastuzumab. There is an FDA black box warning that trastuzumab cannot be used in concurrent combination with...
    48 KB (4,385 words) - 13:38, 11 January 2024
  • monoclonal antibody (mAb) approved by the EMA. Herzuma is a biosimilar trastuzumab approved by the MFDS for treatment of early and advanced (metastatic)...
    10 KB (672 words) - 09:09, 10 April 2024
  • Thumbnail for Antibody-dependent cellular cytotoxicity
    proteins to activate the NK cell. The effects against solid tumors of trastuzumab and rituximab monoclonal antibodies have been shown in experiments with...
    13 KB (1,661 words) - 22:18, 9 December 2023
  • Thumbnail for Daiichi Sankyo
    Sankyo.” This list is not comprehensive. Oncology Enhertu (trastuzumab deruxtecan, fam-trastuzumab deruxtecan-nxki in the United States only) Ezharmia (valemetostat)...
    29 KB (2,326 words) - 13:59, 3 May 2024
  • Cancer Institute.⁣⁣ He is best known for his research on treatments with trastuzumab in HER2-positive breast cancers. Pivot was born on April 20, 1967, in...
    11 KB (1,127 words) - 17:13, 3 December 2023
  • Thumbnail for Insulin
    Unknown/none Antibodies: Ertumaxomab Pertuzumab Trastuzumab Trastuzumab deruxtecan Trastuzumab duocarmazine Trastuzumab emtansine Kinase inhibitors: Afatinib Lapatinib...
    121 KB (13,799 words) - 06:42, 1 July 2024
  • Thumbnail for Roche
    lymphocytic leukaemia. Hemlibra (emicizumab), for haemophilia A. Herceptin (trastuzumab), for HER-2 positive breast cancer. Hivid (zalcitabine), for HIV-1 infection...
    57 KB (5,236 words) - 09:00, 28 June 2024
  • Thumbnail for Mechanism of action
    likely to respond to treatment. Because the breast cancer medication trastuzumab is known to target protein HER2, for example, tumors can be screened...
    17 KB (1,851 words) - 04:52, 27 May 2024
  • Thumbnail for Erythropoietin
    Unknown/none Antibodies: Ertumaxomab Pertuzumab Trastuzumab Trastuzumab deruxtecan Trastuzumab duocarmazine Trastuzumab emtansine Kinase inhibitors: Afatinib Lapatinib...
    31 KB (3,413 words) - 23:30, 21 June 2024
  • Thumbnail for Barrett's esophagus
    and the efficacy of targeted therapy against the Her-2 receptor with trastuzumab (Herceptin) in the treatment of adenocarcinomas at the gastroesophageal...
    41 KB (4,311 words) - 01:35, 4 July 2024
  • Thumbnail for Deruxtecan
    to specific monoclonal antibody (antibody–drug conjugate), such as: Trastuzumab deruxtecan. It is licensed for the treatment of breast cancer or gastric...
    10 KB (586 words) - 14:33, 26 March 2024