Trichostatin A (TSA) is an organic compound that serves as an antifungal antibiotic and selectively inhibits the class I and II mammalian histone deacetylase...

binding affinity were: hydroxamic acids (or hydroxamates), such as trichostatin A, cyclic tetrapeptides (such as trapoxin B, and the depsipeptides, such...

English) is a compound within the isothiocyanate group of organosulfur compounds. It is produced when the enzyme myrosinase transforms glucoraphanin, a glucosinolate...

plants belonging to the genus Capsicum. It is a potent irritant for mammals, including humans, and produces a sensation of burning in any tissue with which...

lose their -CoAs (or coenzyme A groups), they can form a (covalent) dimer called acetoacetate. β-hydroxybutyrate is a reduced form of acetoacetate, in...

Niacinamide or nicotinamide is a form of vitamin B3 found in food and used as a dietary supplement and medication. As a supplement, it is used orally (swallowed...

a contraceptive. Reproductive warnings have also been issued for men using the drug. The United States Food and Drug Administration has indicated a black...

activities are inhibited by trichostatin A (TSA) and have a zinc dependent active site, whereas Class III enzymes are a family of NAD+-dependent proteins...

out cryptographic trusted timestamping Trichostatin A, an inhibitor of histone deacetylases Trypticase soy agar, a common laboratory plating media Tumor-specific...

Sodium butyrate is a compound with formula Na(C3H7COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including...

panobinostat, trichostatin A, vorinostat), prolactin as well as natural polyphenol compounds like resveratrol and curcumin. Celecoxib, a p38 pathway activator...

Curcumin is a bright yellow chemical produced by plants of the Curcuma longa species. It is the principal curcuminoid of turmeric (Curcuma longa), a member...

3,3′-Diindolylmethane (DIM) is a compound derived from the digestion of indole-3-carbinol, found in cruciferous vegetables, such as broccoli, Brussels...

acid, also known as 3-hydroxybutyric acid or BHB, is an organic compound and a beta hydroxy acid with the chemical formula CH3CH(OH)CH2CO2H; its conjugate...

vorinostat, belinostat, panobinostat, and trichostatin A) are HDAC inhibitors with anti-cancer properties. Fosmidomycin is a natural hydroxamic acid inhibitor...

deacetylase via the epoxide. On the contrary, the inhibition by trichostatin A, which is a known potent inhibitor of histone deacetylase, could be reversible...

C17H22N2O3 (molar mass: 302.368 g/mol) may refer to: Emivirine (MKC-442) Trichostatin A This set index page lists chemical structure articles associated with...

(Vitamin E) Topoisomerase Triiodothyronine (T3) Transmembrane receptor Trichostatin A Trophic hormone Trypsin Tryptophan Tubulin Tunicamycin Tyrosine Ubiquitin...

cultured cells. Limited and inconclusive human studies have been reported. A recent review of the biomedical research literature found that "evidence of...

stimulator in cells. Biological immortality Histone deacetylases or HDACs Trichostatin A PDB: 1szd​; Zhao K, Harshaw R, Chai X, Marmorstein R (June 2004). "Structural...

Sodium oxybate, sold under the brand name Xyrem among others, is a medication used to treat symptoms of narcolepsy: sudden muscle weakness and excessive...

repurposed to treat infections caused by human papillomavirus, or HPV. Trichostatin A "Withdrawal Assessment Report for Vorinostat MSD 100 mg Hard Capsules...

(HDAC inhibitors or HDIs). Marks and others found that drugs such as Trichostatin A and SAHA (vorinostat) can serve as anticancer agents. Marks published...

lowered upon differentiation. Trichostatin A causes the cells to maintain the activity of alkaline phosphatase. Trichostatin A can cause reversible inhibition...

à MM. les rédacteurs des Annales de chimie" (Letter from Mr. Chevreul to the editors of the Annals of Chemistry), Annales de chimie, 94 : 73–79; in a...

be affected many cell generations later. A study showed that, upon inhibition of HDAC enzymes by Trichostatin A, genes inserted next to centric heterochromatin...

drugs: butyrate salts (mainly sodium butyrate), trichostatin A, valproic acid, and SAHA; butyric acid is a naturally occurring short-chain fatty acid in...

circadian clock.Trichostatin A has proven to be beneficial when treating sleep deprivation. Since it is an HDAC inhibitor, Trichostatin A has been shown...

sold under the brand name Duvyzat is a medication used for the treatment of Duchenne muscular dystrophy. It is a histone deacetylase inhibitor with potential...

5-dithia-1,7-octadiene) is an organosulfur compound derived from garlic and a few other plants in the genus Allium. Along with diallyl trisulfide and diallyl...