Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor...
40 KB (4,319 words) - 02:54, 11 August 2024
Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...
27 KB (3,264 words) - 05:43, 13 April 2024
Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase...
32 KB (3,935 words) - 05:52, 22 September 2024
'track') stands for tropomyosin receptor kinase or tyrosine receptor kinase (and not "tyrosine kinase receptor" nor "tropomyosin-related kinase", as has been...
27 KB (3,122 words) - 21:45, 8 July 2024
Tropoflavin (category TrkB agonists)
selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB) (Kd ≈ 320 nM), the main signaling receptor of the neurotrophin brain-derived neurotrophic...
21 KB (2,226 words) - 09:52, 3 October 2024
peptide receptor is a type of receptor which binds one or more signaling peptides or signaling proteins. An example is the tropomyosin receptor kinase B (TrkB)...
13 KB (706 words) - 20:05, 20 August 2024
Anaplastic lymphoma kinase (ALK) also known as ALK tyrosine kinase receptor or CD246 (cluster of differentiation 246) is an enzyme that in humans is encoded...
48 KB (5,299 words) - 01:24, 9 March 2024
Brain-derived neurotrophic factor (category TrkB agonists)
appears to upregulate BDNF and tropomyosin receptor kinase B (TrkB) expression as well. BDNF binds at least two receptors on the surface of cells that are...
46 KB (5,344 words) - 03:26, 11 August 2024
R13 (drug) (category TrkB agonists)
active, potent, and selective agonist of the tropomyosin receptor kinase B (TrkB) – the main signaling receptor for the neurotrophin brain-derived neurotrophic...
5 KB (261 words) - 13:14, 3 December 2023
R7 (drug) (category TrkB agonists)
active, potent, and selective agonist of the tropomyosin receptor kinase B (TrkB) – the main signaling receptor for the neurotrophin brain-derived neurotrophic...
9 KB (692 words) - 17:17, 8 June 2024
Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
35 KB (3,831 words) - 18:08, 20 August 2024
Eutropoflavin (category TrkB agonists)
spinal cord as well as antidepressant-like effects in animals. Tropomyosin receptor kinase B § Agonists Liu X, Chan CB, Jang SW, Pradoldej S, Huang J, He...
5 KB (334 words) - 22:50, 3 December 2023
chondroitinase treatment promotes plasticity by activation of Tropomyosin receptor kinase B, receptor for Brain-derived neurotrophic factor and a major plasticity...
5 KB (564 words) - 16:11, 8 June 2023
Vitamin B3 (redirect from Vitamin B-3)
neuro-protective brain-derived neurotrophic factor or its receptor tropomyosin receptor kinase B; or, E) changes to genome expression directly due to the...
38 KB (3,446 words) - 12:11, 23 August 2024
signalling cascade that triggers protein kinase A activation by first binding to a G protein–coupled receptor (GPCR) on the target cell. When a GPCR is...
27 KB (2,665 words) - 17:03, 6 April 2024
In enzymology, a tropomyosin kinase (EC 2.7.11.28) is an enzyme that catalyzes the chemical reaction ATP + tropomyosin ⇌ {\displaystyle \rightleftharpoons...
2 KB (191 words) - 16:09, 26 August 2023
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
46 KB (5,492 words) - 14:52, 20 August 2024
The IκB kinase (IkappaB kinase or IKK) is an enzyme complex that is involved in propagating the cellular response to inflammation, specifically the regulation...
14 KB (1,447 words) - 09:31, 22 December 2023
GDNF. ALTO-100 has been found to increase signaling of the tropomyosin receptor kinase B (TrkB) pathway, and antibodies against BDNF and SCF have been found...
39 KB (3,854 words) - 21:20, 3 September 2024
approximately 25% in mice. BDNF, signaling through its receptor tropomyosin receptor kinase B (TrkB), has been highly implicated in protecting against depression...
25 KB (2,463 words) - 13:50, 27 September 2024
protein-coupled receptor kinases (GPCRKs, GRKs) are a family of protein kinases within the AGC (protein kinase A, protein kinase G, protein kinase C) group of...
18 KB (2,053 words) - 10:12, 12 August 2024
G-protein-coupled receptor kinase 2 (GRK2) is an enzyme that in humans is encoded by the ADRBK1 gene. GRK2 was initially called Beta-adrenergic receptor kinase (βARK...
14 KB (1,637 words) - 11:17, 19 June 2022
Nerve growth factor (redirect from Receptor, nerve growth factor)
binds with at least two classes of receptors: the tropomyosin receptor kinase A (TrkA) and low-affinity NGF receptor (LNGFR/p75NTR). Both are associated...
24 KB (2,872 words) - 06:27, 22 July 2024
serine/threonine kinases should sit in. Types include those acting directly as membrane-bound receptors (Receptor protein serine/threonine kinase) and intracellular...
14 KB (1,210 words) - 13:35, 14 June 2024
5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
65 KB (7,149 words) - 04:45, 26 August 2024
Ketamine (category D2-receptor agonists)
AMPA receptors include upregulation of brain-derived neurotrophic factor (BDNF) and activation of its signaling receptor tropomyosin receptor kinase B (TrkB)...
117 KB (11,361 words) - 06:39, 30 September 2024
proteins, MAP kinase, transcription factor inhibitor IκB, the vitamin D3 receptor VDR, Raf kinase, calpain, and the epidermal growth factor receptor. Upon activation...
27 KB (2,716 words) - 12:30, 12 September 2024
Semax (category Melanocortin receptor antagonists)
brain-derived neurotrophic factor (BDNF) and its signaling receptor tropomyosin receptor kinase B (TrkB) in the hippocampus, and rapidly activates serotonergic...
17 KB (1,521 words) - 03:50, 9 September 2024
Diosmetin (category TrkB agonists)
been found to act as a weak TrkB receptor agonist. Diosmetin is the aglycone of diosmin. Tropomyosin receptor kinase B § Agonists Andreeva, O. A.; Ivashev...
3 KB (145 words) - 02:14, 29 July 2023
resulting in increased signaling through its receptor tyrosine kinase, tropomyosin receptor kinase B (TrkB). Since BDNF is capable of crossing the blood–brain...
94 KB (9,655 words) - 03:24, 11 August 2024