L-Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins...
26 KB (2,535 words) - 02:54, 24 July 2024
Of the 90 unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been...
28 KB (3,078 words) - 07:46, 3 June 2024
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions...
43 KB (5,251 words) - 10:44, 24 June 2024
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine...
38 KB (4,401 words) - 19:13, 28 June 2024
Tyrosine phosphorylation is the addition of a phosphate (PO43−) group to the amino acid tyrosine on a protein. It is one of the main types of protein phosphorylation...
17 KB (2,099 words) - 00:30, 24 November 2022
The enzyme tyrosine decarboxylase (EC 4.1.1.25) catalyzes the chemical reaction L-tyrosine ⇌ {\displaystyle \rightleftharpoons } tyramine + CO2 Hence...
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N-Acetyl-L-tyrosine is an amino acid, an N-acetyl derivative of tyrosine. It is used for parenteral nutrition and as a dietary supplement. Acetylcarnitine...
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Bruton's tyrosine kinase (abbreviated Btk or BTK), also known as tyrosine-protein kinase BTK, is a tyrosine kinase that is encoded by the BTK gene in humans...
22 KB (2,389 words) - 06:43, 22 April 2024
Tyrosine aminotransferase (or tyrosine transaminase) is an enzyme present in the liver and catalyzes the conversion of tyrosine to 4-hydroxyphenylpyruvate...
8 KB (965 words) - 03:44, 22 December 2023
In biochemistry, tyrosine sulfation is a posttranslational modification where a sulfate group (−SO3) is added to a tyrosine residue of a protein molecule...
8 KB (747 words) - 04:45, 28 March 2024
fight-or-flight response. Tyrosine is created from phenylalanine by hydroxylation by the enzyme phenylalanine hydroxylase. Tyrosine is also ingested directly...
20 KB (2,075 words) - 08:55, 17 July 2024
A tyrosine kinase inhibitor (TKI) is a pharmaceutical drug that inhibits tyrosine kinases. Tyrosine kinases are enzymes responsible for the activation...
10 KB (1,179 words) - 18:31, 8 August 2024
α-Methyl-p-tyrosine (AMPT), or simply α-methyltyrosine, also known in its chiral 2-(S) form as metirosine, is a tyrosine hydroxylase enzyme inhibitor...
24 KB (2,255 words) - 08:47, 18 May 2024
Tyrosine hydroxylase deficiency (THD) is a disorder caused by disfunction of tyrosine hydroxylase, an enzyme involved in the biosynthesis of dopamine...
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Tyrosine ammonia lyase (EC 4.3.1.23, L-tyrosine ammonia-lyase, TAL or Tyrase) is an enzyme in the natural phenols biosynthesis pathway. It transforms...
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cluster region BCR gene of chromosome 22, coding for a hybrid protein: a tyrosine kinase signaling protein that is "always on", causing the cell to divide...
29 KB (3,538 words) - 15:01, 5 December 2023
enzymology, a tubulin—tyrosine ligase (EC 6.3.2.25) is an enzyme that catalyzes the chemical reaction ATP + detyrosinated α-tubulin + L-tyrosine ⇌ {\displaystyle...
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Tyrosinemia (redirect from Tyrosine-oxidase temporary deficiency)
inborn, in which the body cannot effectively break down the amino acid tyrosine. Symptoms of untreated tyrosinemia include liver and kidney disturbances...
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KIT (gene) (redirect from Tyrosine kinase mutation)
Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation...
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Methionyl-tyrosine is a dipeptide consisting of the amino acids methionine and tyrosine. Methionyl-tyrosine has been detected, but not quantified in,...
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groups of serines and threonines in their targets. Most of the others are tyrosine kinases, although additional types exist. Protein kinases are also found...
15 KB (1,635 words) - 23:25, 13 August 2024
animals that utilize l-DOPA, make it via biosynthesis from the amino acid l-tyrosine. l-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine...
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biochemically form proteins coded for by DNA. Phenylalanine is a precursor for tyrosine, the monoamine neurotransmitters dopamine, norepinephrine (noradrenaline)...
28 KB (2,386 words) - 21:26, 25 July 2024
PTPN1 (redirect from Protein tyrosine phosphatase 1B)
Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the founding member of the...
24 KB (2,731 words) - 21:47, 24 April 2024
and therefore do not have pKas, with the exception of tyrosine (Tyr, Y). The hydroxyl of tyrosine can deprotonate at high pH forming the negatively charged...
98 KB (10,138 words) - 04:23, 20 August 2024
SH2 domain (redirect from Sh2 domain-containing protein tyrosine phosphatase)
intracellular signal-transducing proteins. SH2 domains bind to phosphorylated tyrosine residues on other proteins, modifying the function or activity of the SH2-containing...
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Protein kinase inhibitor (redirect from VEGFR tyrosine kinase inhibitor)
threonine, or tyrosine amino acids on the protein. Most kinases act on both serine and threonine, the tyrosine kinases act on tyrosine, and a number (dual-specificity...
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donor, such as ATP, to tyrosine residues in proteins. Non-receptor tyrosine kinases are a subgroup of protein family tyrosine kinases, enzymes that can...
21 KB (2,716 words) - 15:11, 26 August 2023
Tyrosine N-monooxygenase (EC 1.14.13.41, tyrosine N-hydroxylase, CYP79A1) is an enzyme with systematic name L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating)...
4 KB (449 words) - 16:11, 26 August 2023
Non-catalytic tyrosine-phosphorylated receptors (NTRs), also called immunoreceptors or Src-family kinase-dependent receptors, are a group of cell surface...
22 KB (2,445 words) - 07:22, 8 April 2024