U.S. Route 69 (US 69) is a major north–south United States highway in the central United States. When it was first created, it was only 150 miles (241 km)...

U.S. Route 69 (US 69) is a major north-south U.S. Highway in the U.S. state of Oklahoma. It extends the corridor formed by U.S. Route 75 in Texas, from...

U.S. Route 69 (US 69) is a north–south United States highway that runs from [[Port Arthur, Texas to Denison ,Texas. In Texas, US 69 runs from Port Arthur...

U.S. Route 69 (US-69) is a major north-south U.S. Highway that runs from Port Arthur, Texas to Albert Lea, Minnesota. In Kansas, the highway runs in the...

U.S. Route 169 (US 169) is a north-south U.S highway that currently runs for 966 miles (1,555 km) from the city of Virginia, Minnesota, to Tulsa, Oklahoma...

U.S. Route 65 (US 65) is a north–south United States highway in the southern and midwestern United States. The southern terminus of the route is at U...

U.S. Route 266 (US 266) is a 43.09-mile (69.35 km), east–west U.S. Numbered Highway in Okmulgee, McIntosh, and Muskogee counties in Oklahoma, United States...

U.S. Route 59 (US 59) is a north–south United States highway (though it was signed east–west in parts of Texas). A latecomer to the U.S. numbered route...

U.S. Route 380 (US 380) is an east–west United States highway. The highway's eastern terminus is in Greenville, Texas at an intersection with Interstate...

U.S. Route 27 or U.S. Highway 27 (US 27) is a north–south United States Numbered Highway in the Southern and Midwestern U.S. The southern terminus is...

U.S. Route 51 or U.S. Highway 51 (US 51) is a major south–north United States highway that extends 1,277 miles (2,055 km) from the western suburbs of New...

U.S. Route 160 (US 160) is a 1,465-mile-long (2,358 km) east–west United States Numbered Highway in the Midwestern and Western United States. The western...

was taken over by U.S. Route 69 in 1934. US 271's original northern terminus was at an intersection with U.S. Route 64 and U.S. Route 71 in Fort Smith...

U.S. Route 466 (US 466) was an east–west United States highway. Though it reached a length of around 500 miles (805 km), the route was co-signed with other...

U.S. Route 20 or U.S. Highway 20 (US 20) is an east–west United States Numbered Highway that stretches from the Pacific Northwest east to New England....

U.S. Route 136 is an east-west U.S. highway that is a spur route of U.S. Route 36. It runs from Edison, Nebraska, at U.S. Route 6 and U.S. Route 34 to...

U.S. Route 150 (US 150) is a 571-mile (919 km) long northwest–southeast United States highway, signed as east–west. It runs from U.S. Route 6 outside...

U.S. Route 73 (US 73) is a north–south United States highway that runs for 113 miles (182 km) from northeast Kansas to southeast Nebraska. The highway's...

U.S. Route 75 is a north–south U.S. Highway that runs 1,239 miles (1,994 km) in the central United States. The highway's northern terminus is located at...

U.S. Route 166 (US 166) is a 164-mile (264 km) east–west United States highway. This route and US 266 are the only two remaining spurs of historic U.S...

U.S. Route 64 (US 64) is an east–west United States highway that runs for 2,281 miles (3,672 km) from Nags Head in eastern North Carolina to just southwest...

U.S. Route 60 is a major east–west United States highway, traveling 2,655 miles (4,273 km) from southwestern Arizona to the Atlantic Ocean coast in Virginia...

U.S. Route 77 (US 77) is a major north–south United States Numbered Highway which extends for 1,305 miles (2,100 km) in the central United States. As...

routes cross I-24 / I-69 before separating in Eddyville. The route intersects KY 70 in Fredonia. The US 641 designation ends at US 60 in Marion. U.S....

U.S. Route 287 (US 287) is a north–south (physically northwest–southeast) United States highway. At 1,791 miles (2,882 km) long,[citation needed] it is...

US 59 (Future I-69)/(Future I-369) and US 84 (Future I-69). U.S. Highway 96 is designated by the State of Texas as a major hurricane evacuation route...

U.S. Route 79 (US 79) is a United States highway in the Southern United States. The route is officially considered and labeled as a north–south highway...

U.S. Route 70 or U.S. Highway 70 (US 70) is an east–west United States highway that runs for 2,381 miles (3,832 km) from eastern North Carolina to east-central...

U.S. Route 30 or U.S. Highway 30 (US 30) is an east–west main route of the United States Numbered Highway System, with the highway traveling across the...

U.S. Route 82 (US 82) is an east–west United States highway in the Southern United States. Created on July 1, 1931 across central Mississippi and southern...