• Thumbnail for VAV3
    Guanine nucleotide exchange factor VAV3 is a protein that in humans is encoded by the VAV3 gene. This gene is a member of the VAV gene family. The VAV...
    8 KB (799 words) - 19:47, 1 February 2023
  • Thumbnail for SH2 domain
    STAT5B; STAT6 SUPT6H; SYK TEC; TENC1; TNS; TNS1; TNS3; TNS4; TXK VAV1; VAV2; VAV3 YES1; ZAP70 Phosphotyrosine-binding domains also bind phosphorylated tyrosines...
    13 KB (1,341 words) - 04:09, 6 March 2024
  • Thumbnail for C13orf38
    ubiquitin ligase activity; Ring finger proteins 0.559 VAV3 Guanine nucleotide exchange factor VAV3; Exchange factor for GTP-binding proteins RhoA, RhoG...
    10 KB (842 words) - 16:04, 7 April 2024
  • Thumbnail for Chromosome 1
    cutanea tarda) USP1 (1p31) USP48: Ubiquitin carboxyl-terminal hydrolase 48 VAV3 (1p13) VPS13D: Vacuolar protein sorting-associated protein 13D VTCN1 (1p13)...
    46 KB (3,284 words) - 04:21, 11 April 2024
  • possible explanations for the adaptation of Ethiopians, including CBARA1, VAV3, ARNT2 and THRB. Two of these genes (THRB and ARNT2) are known to play a...
    52 KB (5,652 words) - 18:29, 19 June 2024
  • Thumbnail for Anaplastic lymphoma kinase
    Delsol G, et al. (April 2008). "Activation of Rac1 and the exchange factor Vav3 are involved in NPM-ALK signaling in anaplastic large cell lymphomas". Oncogene...
    48 KB (5,299 words) - 01:24, 9 March 2024
  • HGNC:29315 Q9HCJ6 18067 VAV1 HGNC:12657 P15498 18068 VAV2 HGNC:12658 P52735 18069 VAV3 HGNC:12659 Q9UKW4 18070 VAX1 HGNC:12660 Q5SQQ9 18071 VAX2 HGNC:12661 Q9UIW0...
    242 KB (17 words) - 23:17, 27 April 2024
  • Thumbnail for ROS1
    L, Chan JL, Trenkle T, McClelland M, Welsh J, Wang LH (December 2000). "Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity...
    29 KB (3,680 words) - 06:37, 4 September 2023
  • Thumbnail for Pleckstrin homology domain
    SYNGAP1, TBC1D2, TEC, TIAM1, TRIO, TRIOBP, TYL, URP1, URP2, VAV1, VAV2, VAV3, VEPH1 Pleckstrin The unrelated FYVE domain binds Phosphatidylinositol 3-phosphate...
    14 KB (1,434 words) - 15:11, 10 June 2024
  • Thumbnail for Organisms at high altitude
    several other genes appear to be involved in Ethiopians, including CBARA1, VAV3, ARNT2 and THRB, which are known to play a role in HIF genetic functions...
    52 KB (5,491 words) - 09:14, 3 December 2023
  • bound pathogens or cells. In humans there are three Vav proteins: Vav1 Vav2 Vav3 Bustelo, X. R. (March 2000). "Regulatory and Signaling Properties of the...
    2 KB (186 words) - 13:35, 27 June 2022
  • Thumbnail for Calponin homology domain
    SPTBN4, SPTBN5, SYNE1, SYNE2, TAGLN, TAGLN2, TAGLN3, UTRN, and VAV1, VAV2, VAV3 PDB: 2RR8​; Umemoto R, Nishida N, Ogino S, Shimada I (September 2010). "NMR...
    5 KB (430 words) - 12:57, 3 December 2023
  • Thumbnail for Neurotrophin-4
    Thomas R, Chakrabarti S (October 2010). "Variations in NTF4, VAV2, and VAV3 genes are not involved with primary open-angle and primary angle-closure...
    11 KB (1,241 words) - 12:35, 9 January 2024
  • on unique functions. Pearce, A. C., Y. A. Senis, et al. (2004). "Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen...
    4 KB (544 words) - 16:28, 26 March 2023
  • Thumbnail for GRB2
    proto-oncogene, SH2B1, SH3KBP1, SHC1, SOS1, Src, Syk, TNK2, TrkA, VAV1, VAV2, VAV3, and Wiskott-Aldrich syndrome protein. MAPK/ERK pathway GRCh38: Ensembl release...
    82 KB (9,365 words) - 15:39, 31 March 2024
  • Thumbnail for C1 domain
    ROCK1; ROCK2; STAC; STAC2; STAC3; TENC1; UNC13A; UNC13B; UNC13C; VAV1; VAV2; VAV3; Azzi A, Boscoboinik D, Hensey C (1992). "The protein kinase C family". Eur...
    3 KB (321 words) - 23:35, 12 August 2023
  • different gene candidates underlying adaptation to high altitude (CBARA1, VAV3, ARNT2, and THRB). This study demonstrates another example of convergent...
    36 KB (4,150 words) - 20:13, 8 November 2023
  • Thumbnail for RhoGEF domain
    PREX1; PREX2; RASGRF1; RASGRF2; SPATA13; TIAM1; TIAM2; TRIO; VAV1; VAV2; VAV3. DOCK1/DOCK180; DOCK2; DOCK3/MOCA; DOCK4; DOCK5; DOCK6/ZIR1; DOCK7/ZIR2;...
    7 KB (526 words) - 13:40, 16 October 2023
  • Thumbnail for SH2B2
    NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity". Oncogene. 21 (50): 7720–9. doi:10.1038/sj.onc...
    8 KB (994 words) - 00:01, 4 March 2023
  • Thumbnail for RhoG
    migration). Other GEFs reported to interact with RhoG include Dbs, ECT2, VAV2 and VAV3. There have been very few interactions reported between RhoG and negative...
    23 KB (2,844 words) - 15:52, 11 April 2024