18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2 gene. SLC18A2 is...

treat tardive dyskinesia. It acts as a vesicular monoamine transporter 2 (VMAT2) inhibitor. Valbenazine is used to treat tardive dyskinesia in adults. Tardive...

heredity and that a specific gene, called vesicular monoamine transporter 2 (VMAT2), predisposes humans towards spiritual or mystic experiences. The idea has...

rat adrenal medulla cells, whereas VMAT2 is the major transporter in bovine adrenal medulla cells. VMAT1 and VMAT2 are acidic glycoproteins with a molecular...

amine-associated receptor 1 (hTAAR1) and vesicular monoamine transporter 2 (VMAT2) in neurons. Dextroamphetamine is a more potent Central nervous system (CNS)...

for the presynaptic vesicular monoamine transporter, VMAT2. Following amphetamine uptake at VMAT2, amphetamine induces the collapse of the vesicular pH...

synapses as well. Phentermine may also trigger the release of monoamines from VMAT2, which is a common pharmacodynamic effect among substituted amphetamines...

VMAT1 and VMAT2. VMAT1 is mostly expressed in neuroendocrine cells. VMAT2 is mostly expressed in neurons. Thus, it is the blockade of neuronal VMAT2 by reserpine...

Amphetamine and many of the other substituted amphetamines are inhibitors of VMAT2 and potent agonists of the trace amine-associated receptor 1 (TAAR1); agonism...

of vesicular monoamine transporter 2 (VMAT2) also known as solute carrier family 18 member 2 (SLC18A2). VMAT2 is a protein which depletes dopamine (DA)...

TAAR1, a presynaptic G protein-coupled receptor, and binding to a site on VMAT2, a type of monoamine transporter located on synaptic vesicles within monoamine...

such as the dopamine transporter (DAT), vesicular monoamine transporter 2 (VMAT2), and dopamine receptors can be classified as dopaminergic, and neurons...

transporters, methamphetamine inhibits synaptic vesicle function by inhibiting VMAT2, which prevents monoamine uptake into the vesicles and promotes their release...

amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter...

monoamine transporter, vesicular monoamine transporter 2 (VMAT2). When amphetamine is taken up by VMAT2, the vesicle releases (effluxes) dopamine molecules...

dose) in a PET study. Bupropion has also been shown to increase striatal VMAT2, though it is unknown if this effect is more pronounced than other DRIs...

07109.x. PMC 3005101. PMID 21073468. Eiden LE, Weihe E (January 2011). "VMAT2: a dynamic regulator of brain monoaminergic neuronal function interacting...

CNS and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. When VMAT2 is inhibited monoamine neurotransmitters such as dopamine...

potential-evoked neurotransmitter release. Inside the neuron, MDMA inhibits VMAT2 and activates TAAR1. TAAR1 agonism results in the phosphorylation of monoamine...

transport at vesicular monoamine transporters (specifically, VMAT1 and VMAT2) and other monoamine transporters that are located along the plasma membrane...

bipolar disorder as well as symptoms of mania, implicating dopamine in mania. VMAT2 binding was found to be increased in one study of people with bipolar mania...

synaptic vesicles by a solute carrier—a vesicular monoamine transporter, VMAT2. Dopamine is stored in these vesicles until it is ejected into the synaptic...

a mutation in SLC18A2, which encodes vesicular monoamine transporter 2 (VMAT2). "dysdiadochokinesia". Merriam-Webster.com Dictionary. Merriam-Webster...

are used as PET radioligands for examining VMAT2. [11C]DTBZ as a PET radioligand with affinity for VMAT2 was developed in the mid 1990s by David E. Kuhl...

outer cell membrane and the vesicular monoamine transporter (VMAT1 and VMAT2) in the membrane of intracellular vesicles.[citation needed] After release...

inhibiting reuptake by the vesicular monoamine transporters, VMAT1 and VMAT2. Examples of monoamine-depleting agents include deutetrabenazine, oxypertine...

containing monoamines, enhancing their uptake, and is co-expressed with VMAT2 and VAChT. GRCh38: Ensembl release 89: ENSG00000145248 – Ensembl, May 2017...

as both compounds induce efflux from vesicular monoamine transporter 2 (VMAT2) and activate TAAR1 with comparable efficacy. Like dopamine, norepinephrine...

electrochemical gradient created by a vesicular hydrogen proton-ATPase. VMAT1 and VMAT2 are two isoforms that can transport monoamines such as serotonin, norepinephrine...

the reuptake and release of dopamine into the Nacc via interactions with VMAT2 and TAAR1 in the axon terminal of mesolimbic dopamine neurons. Glucocorticoids...