• Thumbnail for Vinblastine
    Vinblastine (VBL), sold under the brand name Velban among others, is a chemotherapy medication, typically used with other medications, to treat a number...
    19 KB (1,703 words) - 05:39, 9 August 2024
  • Thumbnail for Catharanthus roseus
    pantropical distribution. It is a source of the drugs vincristine and vinblastine, used to treat cancer. It was formerly included in the genus Vinca as...
    27 KB (2,647 words) - 19:29, 6 October 2024
  • Thumbnail for Mitotic inhibitor
    frequently used in the treatment of cancer include paclitaxel, docetaxel, vinblastine, vincristine, and vinorelbine. Colchicine and griseofulvin are mitotic...
    59 KB (6,992 words) - 22:40, 13 August 2024
  • doxorubicin/hydroxydaunorubicin, designated as H in CHOP) Bleomycin Vinblastine Dacarbazine (similar to procarbazine, designated as P in MOPP and in...
    20 KB (2,368 words) - 21:01, 26 September 2024
  • Thumbnail for Vinca
    as several other types of cancer and some non-cancerous conditions. Vinblastine is a chemical analogue of vincristine and is also used to treat various...
    16 KB (1,327 words) - 18:38, 5 January 2024
  • Thumbnail for Metabolic pathway
    roseus, which are then chemically converted into vinblastine. The biosynthetic pathway to produce vinblastine, including 30 enzymatic steps, has been transferred...
    26 KB (3,001 words) - 22:09, 5 July 2024
  • Thumbnail for Vinca alkaloid
    alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine and vincristine, all of which can be obtained from the plant. The newer...
    10 KB (934 words) - 10:47, 16 August 2023
  • Thumbnail for Vincristine
    biologically active, the two most significant being vincristine and vinblastine. Its use as an anti-tumor, anti-mutagenic agent is well documented in...
    31 KB (2,832 words) - 13:30, 20 September 2024
  • Thumbnail for Indole alkaloid
    (calicantine); Splitting of the functional group of one of the monomers (vinblastine, vincristine). Apart from bisindole alkaloids, dimeric alkaloids exist...
    34 KB (3,388 words) - 02:44, 6 September 2024
  • Oxaliplatin Nedaplatin Satraplatin Alitretinoin Bexarotene Tretinoin Vinblastine Vincristine Vindesine Vinorelbine Abraxane Actinomycin Alitretinoin All-trans...
    5 KB (324 words) - 12:07, 20 July 2024
  • Thumbnail for Catharanthus
    alkaloids. The plant produces about 130 of these compounds, including vinblastine and vincristine, two drugs used to treat cancer. Catharanthus roseus...
    5 KB (459 words) - 20:27, 14 October 2023
  • Thumbnail for Dimerization of catharanthine and vindoline
    (Catharanthus roseus) whose dimerization produces the anti-cancer drugs vinblastine and vincristine. The precursor of catharanthine and vindoline is strictosidine...
    8 KB (1,063 words) - 12:49, 12 September 2024
  • Thumbnail for Monomethyl auristatin E
    and solid tumors. These drugs show potency of up to 200 times that of vinblastine, another antimitotic drug used for Hodgkin lymphoma as well as other...
    9 KB (649 words) - 22:01, 12 August 2023
  • Thumbnail for Pronucleus
    fusion of the pronuclei. Vinblastine is a chemotherapy drug that affects both the plus and minus ends of microtubules. When vinblastine is added to the ovum...
    10 KB (1,340 words) - 23:42, 12 August 2023
  • Thumbnail for Vindoline
    Vindoline is a chemical precursor to vinblastine. Vindoline is formed through biosynthesis from Tabersonine. Lochnericine Dimerization of catharanthine...
    2 KB (74 words) - 09:25, 24 August 2024
  • (physician) (1910–1990), Canadian physician involved in the discovery of vinblastine Robert Noble (company), Scottish textile company established 1666 Robert...
    865 bytes (133 words) - 03:19, 24 October 2024
  • Thumbnail for Madagascar
    are used as herbal remedies for a variety of afflictions. The drugs vinblastine and vincristine are vinca alkaloids, used to treat Hodgkin lymphoma,...
    225 KB (21,052 words) - 10:47, 2 November 2024
  • doxorubicin, bleomycin, vinblastine, and dacarbazine) versus A+AVD (a combination of brentuximab vedotin plus AVD, or doxorubicin, vinblastine, and dacarbazine)...
    22 KB (2,065 words) - 15:03, 2 September 2024
  • researcher who in the 1950s helped with the discovery of vincristine and vinblastine, widely used anti-cancer drugs. Source: Canadian Cancer Society 2022...
    2 KB (199 words) - 11:43, 29 October 2023
  • Very large board, a large printed circuit board Vincaleukoblastine, or vinblastine, an antitumor alkaloid VLB Berlin (Versuch- u. Lehranstalt für Brauerei...
    484 bytes (91 words) - 04:22, 25 June 2023
  • Anti-Communist Volunteer Militia MVAC chemotherapy regimen of (methotrexate, vinblastine, adriamycin and cisplatin) MVAC mechanical ventilation and air conditioning...
    447 bytes (77 words) - 18:57, 6 April 2024
  • Thumbnail for Dacarbazine
    Hodgkin's lymphoma. For Hodgkin's lymphoma it is often used together with vinblastine, bleomycin, and doxorubicin. It is given by injection into a vein. Common...
    12 KB (1,065 words) - 23:06, 26 January 2024
  • Thumbnail for Catharanthine
    currently unknown. Catharanthine is one of the two precursors that form vinblastine, the other being vindoline. (+)-Catharanthine competitively inhibits...
    5 KB (358 words) - 09:24, 24 August 2024
  • Thumbnail for Bob Champion
    with an orchidectomy and with the chemotherapeutic drugs bleomycin, vinblastine and cisplatin, and also had an exploratory operation to identify cancer...
    5 KB (525 words) - 08:39, 13 June 2024
  • Thumbnail for Chemotherapy
    original vinca alkaloids are natural products that include vincristine and vinblastine. Following the success of these drugs, semi-synthetic vinca alkaloids...
    155 KB (17,518 words) - 23:36, 26 October 2024
  • study in non-small-cell lung cancer comparing cisplatin, ifosfamide, vinblastine (VIP) versus cisplatin, ifosfamide and etoposide (VIP-16). Hellenic Co-Operative...
    23 KB (634 words) - 23:47, 16 August 2024
  • 1990) was a Canadian physician who was involved in the discovery of vinblastine. Born in Toronto, Ontario, he received his M.D. from the University of...
    3 KB (148 words) - 10:12, 7 September 2023
  • Thumbnail for P-glycoprotein
    inhibitors (i.e. etoposide, doxorubicin), microtubule-targeted drugs (i.e. vinblastine), and tyrosine kinase inhibitors (i.e. gefitinib, sunitinib). Lipids...
    33 KB (3,930 words) - 21:04, 3 September 2024
  • Thumbnail for Transitional cell carcinoma
    consists of gemcitabine and cisplatin) or a combination of methotrexate, vinblastine, adriamycin, and cisplatin (MVAC polychemotherapy). The side effects...
    19 KB (1,970 words) - 15:42, 9 August 2024
  • Thumbnail for Vinorelbine
    alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine and vincristine, all of which can be obtained from the plant. The newer...
    15 KB (1,291 words) - 08:14, 27 August 2024