X-box binding protein 1, also known as XBP1, is a protein which in humans is encoded by the XBP1 gene. The XBP1 gene is located on chromosome 22 while...
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in insulin secretion and peripheral insulin resistance. Abnormalities in XBP1 lead to a heightened endoplasmic reticulum stress response and subsequently...
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transautophosphorylation. The activated domain is able to activate the transcription factor XBP1(Xbox binding protein) mRNA (the mammalian equivalent of the yeast Hac1 mRNA)...
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real-time RT-PCR to measure the rate at which XBP1 is cleaved by IRE1 when the UPR is activated. XBP1 mRNA cleavage leads to the translation of a transcription...
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for most of them. For example, one association is with mutations in the XBP1 gene, which is involved in the unfolded protein response pathway of the endoplasmic...
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animal is an unconventional bZIP intron in animals located in the mRNA of Xbp1 orthologs. The RNA structure consists of two hairpins of similar length with...
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BZIP intron RNA motif (redirect from Hac1 Xbp1 intron)
a non-canonical intron from bZIP-containing genes called HAC1 in yeast, XBP1 in Metazoa, Hxl1 or Cib1 in Basidiomycota and bZIP60 in plants. Splicing...
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are, e.g., 5-HTTLPR in the serotonin transporter gene and gene variants in XBP1. Cloninger argued that the Five Factor model does not assess domains of personality...
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ENSG00000184937 C2H2 ZF Known motif – High-throughput in vitro [1,007] BGGGGGRG XBP1 ENSG00000100219 bZIP Known motif – High-throughput in vitro [1,008] GVTGACGTGKCVHW...
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splicing activity, removing an intron from the X-box binding protein 1 (XBP1) mRNA, and allowing it to become translated into a functional transcription...
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deposition and premature adipocyte differentiation takes place. The expression of xbp1, master regulator of osterix gets reduced, suggesting that unfolded proteins...
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DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
39 KB (4,859 words) - 19:32, 22 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
87 KB (9,376 words) - 13:18, 19 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
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Griffiths-Jones S (2011). "Conserved RNA structures in the non-canonical Hac1/Xbp1 intron". RNA Biol. 8 (4): 552–556. doi:10.4161/rna.8.4.15396. PMC 3225973...
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DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
26 KB (3,991 words) - 05:29, 10 July 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
12 KB (1,317 words) - 20:08, 28 August 2023
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
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DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
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DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
41 KB (4,385 words) - 21:28, 21 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
42 KB (4,829 words) - 16:45, 1 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
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differential expression. His work also showed that the bZIP transcription factor: XBP1 forms a hetero-dimer with c-Fos. This has turned out to be relevant to the...
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DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
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DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
57 KB (7,191 words) - 06:17, 25 July 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
75 KB (8,057 words) - 04:44, 25 July 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
16 KB (1,910 words) - 01:56, 10 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
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the maturation of B-cells toward plasma cells (e.g. CD38, CD138, IR4/MUM1, XBP1, IL21R, and, as just indicated, PRDM1); and 6) reduced expression of genes...
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JUN, KLF6, KLF7, MYC, SMAD1, SMAD2, SMAD3, SOX11, SRF, STAT3, TP53, and XBP1. Several of these can also boost the regenerative capacity of CNS neurons...
34 KB (4,113 words) - 01:03, 12 July 2024