• Thumbnail for YAP1
    YAP1 (yes-associated protein 1), also known as YAP or YAP65, is a protein that acts as a transcription coregulator that promotes transcription of genes...
    30 KB (3,445 words) - 13:46, 19 August 2024
  • Thumbnail for Poroma
    contain at least one of two YAP1 fusion genes, i.e. abnormal genes caused by a mutation which merges a part of the YAP1 gene fused to part of either...
    20 KB (2,243 words) - 21:17, 6 January 2024
  • Thumbnail for Fungus
    oxidative burst with an oxidative stress response, regulated by the gene YAP1. The response protects U. maydis from the host defense, and is necessary...
    200 KB (19,174 words) - 03:56, 29 September 2024
  • STRA6 TBC1D20 TBC1D32 TBX22 TCOF1 TENM3 TFAP2A TMEM98 TMEM67 TMX3 VAX1 VSX2 YAP1 ZEB2 ZIC2 SOX2 has been implicated in a substantial number (10–15%) of cases...
    25 KB (2,173 words) - 09:44, 18 March 2024
  • Sasajima Y, Goshima N, Yamazaki N, Mori T (May 2019). "Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma". The Journal of Clinical...
    32 KB (3,864 words) - 09:20, 30 April 2024
  • Thumbnail for Siyi
    Jiangmen. An alternative term, Wuyi (Chinese: 五邑; pinyin: Wǔyì, Cantonese: Ng5 Yap1; 'five counties'), which refers to the five former counties of Xinhui, Taishan...
    9 KB (1,009 words) - 17:41, 1 July 2024
  • Thumbnail for Marius Sudol
    been to understand signaling modalities of WW domain-containing YAP (aka YAP1) oncoprotein and crosstalk of other WW domain-containing proteins in the...
    7 KB (479 words) - 21:43, 28 March 2024
  • Thumbnail for Signal transduction
    actin cytoskeleton detects changes and transmits them downstream through YAP1. Calcium-dependent cell adhesion molecules such as cadherins and selectins...
    63 KB (7,609 words) - 04:41, 21 June 2024
  • The YAP1 gene product, yes-associated protein, contributes to the regulation of cell proliferation and apoptosis, i.e. programmed cell death (see YAP1)....
    23 KB (2,718 words) - 08:48, 4 September 2023
  • Thumbnail for SH3 domain
    myosins SH3 and multiple ankyrin repeat domains: SHANK1, SHANK2, SHANK3 YAP1 ARHGAP12 vexin (VXN) TANGO1 Integrase Focal Adhesion Kinase (FAK, PTK2) Proline-rich...
    8 KB (933 words) - 12:56, 10 September 2024
  • Thumbnail for Transcription factor
    stress and alkaline pH sensing were contributed from the transcription factor Yap1 and Rim101 of the Papiliotrema terrestris LS28 as molecular tools revealed...
    73 KB (8,057 words) - 16:30, 24 September 2024
  • Thumbnail for Corn smut
    such an oxidative burst by an oxidative stress response, regulated by gene YAP1. This response protects M. maydis from the host attack, and is necessary...
    27 KB (3,101 words) - 00:03, 13 August 2024
  • Thumbnail for Undifferentiated pleomorphic sarcoma
    member 3 protein, a product of the VGLL3 gene, and YAP1, i.e. yes-associated protein 1, a product of the YAP1 gene, in the Hippo signaling pathway; 2) Abnormal...
    41 KB (4,762 words) - 00:12, 13 June 2024
  • Thumbnail for TMEM61
    both in the same region but both did not promote cancer growth. PMP22 , YAP1. GRCh38: Ensembl release 89: ENSG00000143001 – Ensembl, May 2017 GRCm38:...
    15 KB (1,230 words) - 14:00, 13 May 2024
  • Thumbnail for Endohedral fullerene
    metallofluorenol, can competitively inhibit the WW domain in the oncogene YAP1 from activating. It was originally developed as an MRI contrast agent. Endohedral...
    19 KB (2,240 words) - 14:26, 5 March 2024
  • translocations. During translocations, a fusion protein is formed between YAP1, a gene crucial for proliferation and apoptosis (programmed cell death) of...
    27 KB (3,317 words) - 11:14, 7 January 2024
  • Thumbnail for Histone acetyltransferase
    E2F(1-3), p73α, retinoblastoma (Rb), NF-κB (p50, p65), Smad7, importin-α, Ku70, YAP1, E1A adenovirus protein, and S-HDAg (hepatitis delta virus small delta antigen)...
    53 KB (6,150 words) - 04:41, 26 August 2024
  • Thumbnail for Transcription factor Sp1
    microRNA significantly decreased expression of SP1 and YAP1 in colorectal cancer cells. SP1 and YAP1 mRNAs are direct targets of miR-375-5p. Transcription...
    30 KB (3,444 words) - 11:07, 25 July 2024
  • HGNC:15517 Q9H1B5 18415 YAE1 HGNC:24857 Q9NRH1 18416 YAF2 HGNC:17363 Q8IY57 18417 YAP1 HGNC:16262 P46937 18418 YARS1 HGNC:12840 P54577 18419 YARS2 HGNC:24249 Q9Y2Z4...
    242 KB (17 words) - 18:43, 6 October 2024
  • Thumbnail for Cadherin-1
    Mohseni M, Kirak O, Pruszak J, Rodriguez JR, Zhou D, et al. (March 2011). "Yap1 acts downstream of α-catenin to control epidermal proliferation". Cell. 144...
    54 KB (6,380 words) - 07:38, 8 October 2024
  • Thumbnail for PTK2
    NEO1, P53, PIK3R1, PTEN, PXN, RB1CC1, STAT1, Src, Syk, TGFB1I1, TLN1, TSC2, YAP1. Tyrosine kinase GRCm38: Ensembl release 89: ENSMUSG00000022607 – Ensembl...
    41 KB (4,724 words) - 09:43, 11 December 2023
  • Colobomatous microphthalmia-obesity-hypogenitalism-intellectual disability syndrome YAP1 AD Coloboma, ocular, with or without hearing impairment, cleft lip/palate...
    13 KB (538 words) - 09:46, 18 March 2024
  • the YAP1-NUTM1 and WWTR1-NUTM1 fusion genes in 21 cases and 1 case, respectively, while the same study of 11 porocarcinoma tumors detected the YAP1-NUTM1...
    21 KB (2,602 words) - 00:37, 1 August 2024
  • Thumbnail for WW domain
    by the analysis of two splice isoforms of YAP gene product, named YAP1-1 and YAP1-2, which differed by the presence of an extra 38 amino acids. These...
    23 KB (2,658 words) - 23:14, 25 May 2024
  • Thumbnail for WHO classification of tumours of the central nervous system
    Supratentorial ependymoma, ZFTA fusion-positive 1.6.1.2 Supratentorial ependymoma, YAP1 fusion-positive 1.6.2 Posterior fossa ependymoma 1.6.2.1 Posterior fossa...
    12 KB (1,416 words) - 18:30, 31 July 2024
  • Thumbnail for Vestigial-like family member 3
    G, Chibon F, Ferreira C, Lagarde P, Terrier P, et al. (December 2010). "YAP1 and VGLL3, encoding two cofactors of TEAD transcription factors, are amplified...
    5 KB (566 words) - 05:54, 26 September 2024
  • Thumbnail for ERBB4
    sclerosis type 19. ERBB4 has been shown to interact with: DLG4 NRG1, STAT5A, and YAP1. GRCh38: Ensembl release 89: ENSG00000178568 – Ensembl, May 2017 GRCm38:...
    12 KB (1,597 words) - 14:14, 22 December 2023
  • Thumbnail for WWTR1
    member, TEAD3, TEA domain family member, TEAD4, TEA domain family member YAP1, Yes-associated protein 1 Dimerization dependent transcriptional regulation...
    28 KB (2,383 words) - 05:52, 20 May 2024
  • Thumbnail for TEAD1
    the protein. It allows the binding of cofactors and has been called the YAP1 binding domain, because it is its ability to bind this well-known TEAD proteins...
    33 KB (4,085 words) - 21:04, 2 October 2024
  • Thumbnail for L. S. Shashidhara
    Lingadahalli S. (March 2022). "Analyzing the influence of IL18 in regulation of YAP1 in breast oncogenesis using cBioportal". Cancer Reports. 5 (3): e1484. doi:10...
    29 KB (2,593 words) - 03:45, 20 August 2024