A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) which stabilizes the fold...

Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger...

Zinc finger inhibitors, or zinc ejectors, are substances or compounds that interact adversely with zinc fingers and cause them to release their zinc from...

Interesting New Gene) finger domain is a protein structural domain of zinc finger type which contains a C3HC4 amino acid motif which binds two zinc cations (seven...

engineered nucleases, i.e. all three major classes of these enzymes—zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs)...

EGR-1 (Early growth response protein 1) also known as ZNF268 (zinc finger protein 268) or NGFI-A (nerve growth factor-induced protein A) is a protein...

targeted through ZIP transporters. Zinc serves a purely structural role in zinc fingers, twists and clusters. Zinc fingers form parts of some transcription...

coordinating zinc ions with regularly spaced zinc-coordinating residues (either histidines or cysteines). The most common class of zinc finger (Cys2His2)...

molecular biology the ZZ-type zinc finger domain is a type of protein domain that was named because of its ability to bind two zinc ions. These domains contain...

the AN1-type zinc finger domain, which has a dimetal (zinc)-bound alpha/beta fold. This domain was first identified as a zinc finger at the C terminus...

unintended side effects. Early techniques relied on meganucleases and zinc finger nucleases. Since 2009 more accurate and easier systems to implement have...

protein Zinc finger protein 557 ZNF571: encoding protein Zinc finger protein 571 ZNF576: encoding protein Zinc finger protein 576 Zinc finger protein...

In molecular biology the MIZ-type zinc finger domain is a zinc finger-containing protein with homology to the yeast protein, Nfi-1. Miz1 is a sequence...

protein 648 ZNF669: Zinc finger protein 669 ZNF687: Zinc finger protein 687 ZNF692: Zinc finger protein 692 ZNF695: Zinc finger protein 695 There are...

structural motifs, such as RNA recognition motif (RRM), dsRNA binding domain, zinc finger and others. They are cytoplasmic and nuclear proteins. However, since...

In molecular biology, GATA zinc fingers are zinc-containing domains found in a number of transcription factors (including erythroid-specific transcription...

490 - Zinc finger protein 530 - Zinc finger protein 556 - Zinc finger protein 562 - Zinc finger protein 574 - Zinc finger protein 577 - Zinc finger protein...

biallelic knockouts. Zinc-finger nucleases consist of DNA binding domains that can precisely target a DNA sequence. Each zinc-finger can recognize codons...

Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl...

Zinc deficiency is defined either as insufficient zinc to meet the needs of the body, or as a serum zinc level below the normal range. However, since a...

protein Zinc finger protein 395 ZNF517 encoding protein Zinc finger protein 517 ZNF696 encoding protein Zinc finger protein 696 ZNF703: zinc finger protein...

DNA-binding protein Ikaros also known as Ikaros family zinc finger protein 1 is a protein that in humans is encoded by the IKZF1 gene. Ikaros is a transcription...

Zinc finger E-box-binding homeobox 1 is a protein that in humans is encoded by the ZEB1 gene. ZEB1 (previously known as TCF8) encodes a zinc finger and...

biology, the FLYWCH zinc finger is a zinc finger domain. It is found in a number of eukaryotic proteins. FLYWCH is a C2H2-type zinc finger characterised by...

binding sequence. Because zinc fingers are only 30 amino acids long they are easier to deliver, and multiple zinc fingers can be linked together to target...

cleavage domain with an array of DNA binding proteins or zinc finger arrays, denoted zinc finger nucleases (ZFN), are a powerful tool for host genome editing...

ZmHox1a. The PHD zinc finger motif resembles the metal binding RING domain (Cys3-His-Cys4) and FYVE domain. It occurs as a single finger, but often in clusters...

Zinc finger protein chimera are chimeric proteins composed of a DNA-binding zinc finger protein domain and another domain through which the protein exerts...

encoding protein Zinc finger protein 117 ZNF394: zinc finger protein 394 ZNF398: zinc finger protein 398 ZNF679: encoding protein Zinc finger protein 679 ZNF716:...

Zinc finger transcription factors or ZF-TFs, are transcription factors composed of a zinc finger-binding domain and any of a variety of transcription-factor...