• Thumbnail for 5-HT1B receptor
    5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene. The 5-HT1B receptor is a 5-HT...
    17 KB (1,982 words) - 06:24, 10 July 2024
  • Thumbnail for 5-HT receptor
    which activates 5-HT1A, 5-HT1D, 5-HT1B, D2 and norepinephrine receptors. LSD (a psychedelic) is a 5-HT1A, 5-HT2A, 5-HT2C, 5-HT5A and 5-HT6 agonist. The...
    65 KB (5,263 words) - 10:40, 12 August 2024
  • Thumbnail for Serotonin receptor agonist
    on this receptor. Serenics such as batoprazine, eltoprazine, and fluprazine are agonists of the 5-HT1B receptor and other serotonin receptors, and have...
    16 KB (1,657 words) - 17:23, 8 June 2024
  • Thumbnail for 5-HT1A receptor
    receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT1A...
    58 KB (6,188 words) - 15:33, 22 September 2024
  • including 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F. Receptors of the 5-HT1 type, specifically, the 5-HT1A and 5-HT1D receptor subtypes, are present...
    5 KB (472 words) - 12:54, 25 December 2023
  • Thumbnail for 5-HT1D receptor
    functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity"...
    11 KB (1,237 words) - 06:53, 10 July 2024
  • 5-HT1D receptor agonists are pharmaceutical drugs for the treatment of migraine. They include: Triptans (which additionally act as 5-HT1B receptor agonists)...
    413 bytes (78 words) - 00:39, 25 June 2024
  • 5-HT2A receptor 5-HT2B receptor 5-HT2C receptor 5-HT1 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor Category:5-HT2...
    2 KB (166 words) - 00:47, 13 May 2022
  • Thumbnail for 5-HT6 receptor
    The 5HT6 receptor is a subtype of 5HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5HT). It is a G protein-coupled...
    29 KB (3,308 words) - 15:33, 22 September 2024
  • Thumbnail for Triptan
    Triptan (category 5-HT1D agonists)
    pain. The drugs of this class act as agonists for serotonin 5-HT1B and 5-HT1D receptors at blood vessels and nerve endings in the brain. The first clinically...
    37 KB (3,655 words) - 01:36, 18 August 2024
  • Thumbnail for 5-HT2A receptor
    The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). The 5-HT2A...
    90 KB (9,886 words) - 06:08, 13 September 2024
  • Thumbnail for 5-(Nonyloxy)tryptamine
    5-(Nonyloxy)tryptamine is a tryptamine derivative which acts as a selective agonist at the 5-HT1B receptor. Increasing the O-alkoxy chain length in this...
    3 KB (171 words) - 02:20, 25 July 2022
  • Thumbnail for Serotonin
    different receptors. Through 5-HT1B receptors, it negatively regulates bone mass, while it does so positively through 5-HT2B receptors and 5-HT2C receptors. There...
    131 KB (14,080 words) - 07:22, 5 October 2024
  • Thumbnail for 5-HT2C receptor
    The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT2...
    51 KB (6,101 words) - 01:14, 28 August 2024
  • Thumbnail for CP-94253
    CP-94253 (category Serotonin receptor agonists)
    selective serotonin 5-HT1B receptor agonist, with approximately 25× and 40× selectivity over the closely related 5-HT1D and 5-HT1A receptors. It has a range...
    7 KB (620 words) - 00:29, 10 February 2024
  • serotonin reuptake inhibitor, serotonin 5-HT1A and 5-HT1B receptor agonist, and serotonin 5-HT1D, 5-HT3, and 5-HT7 receptor antagonist [375] Zimelidine (Zelmid)...
    103 KB (8,423 words) - 22:50, 19 October 2024
  • Thumbnail for BRL-15,572
    BRL-15,572 (category 5-HT1D antagonists)
    similar pharmacology to the closely related 5-HT1B receptor, and most older ligands for these receptors bind to both subtypes with approximately equal...
    4 KB (338 words) - 08:02, 1 October 2024
  • Thumbnail for CGS-12066A
    CGS-12066A (category Serotonin receptor agonists)
    agonist for the 5-HT1B receptor with lower affinity for the three 5-HT2 receptor subtypes. It is used for studying the role of the 5-HT1B receptor in various...
    3 KB (254 words) - 12:30, 5 August 2024
  • functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin receptors) which are G protein-coupled receptors. This ion channel is cation-selective...
    22 KB (2,395 words) - 18:29, 18 July 2024
  • Thumbnail for Isamoltane
    Isamoltane (category 5-HT1B antagonists)
    β-adrenergic, 5-HT1A, and 5-HT1B receptors. It has about five times the potency for the 5-HT1B receptor (21 nmol/L) over the 5-HT1A receptor (112 nmol/L)...
    3 KB (200 words) - 21:39, 9 March 2024
  • Thumbnail for Alprenolol
    Alprenolol (category 5-HT1B antagonists)
    Aptol Duriles), is a non-selective beta blocker as well as a 5-HT1A and 5-HT1B receptor antagonist, used in the treatment of angina pectoris. It is no...
    3 KB (144 words) - 19:20, 20 December 2023
  • Thumbnail for Eltoprazine
    Eltoprazine (category 5-HT1B agonists)
    acts as an agonist of the serotonin 5-HT1A and 5-HT1B receptors and as an antagonist of the serotonin 5-HT2C receptor. The drug is closely related to fluprazine...
    4 KB (264 words) - 03:01, 26 September 2024
  • Thumbnail for Anpirtoline
    Anpirtoline (category 5-HT1B agonists)
    C10H13ClN2S) is a synthetic chemical compound used as a 5-HT1B receptor agonist as well as a 5-HT3 receptor antagonist, causing a decrease in serotonin synthesis...
    4 KB (269 words) - 13:54, 30 June 2024
  • Thumbnail for Vortioxetine
    Vortioxetine (category 5-HT1B agonists)
    the serotonin 5-HT1A receptor, partial agonist of the 5-HT1B receptor, and antagonist of the serotonin 5-HT1D, 5-HT3, and 5-HT7 receptors, as well as an...
    56 KB (4,803 words) - 19:52, 31 August 2024
  • Thumbnail for S100A10
    depression. P11 interacts with the serotonin receptor proteins, 5-HT receptors such as 5-HT1B, a receptor involved in the physiological effect of locomotor...
    39 KB (4,728 words) - 15:30, 23 December 2023
  • Thumbnail for CP-93129
    CP-93129 (category Serotonin receptor agonists)
    selective serotonin 5-HT1B receptor agonist, with approximately 150x and 200x selectivity over the closely related 5-HT1D and 5-HT1A receptors. It is used in...
    3 KB (302 words) - 07:30, 12 January 2024
  • Thumbnail for Naphthylpiperazine
    Naphthylpiperazine (category Serotonin receptor antagonists)
    partial agonism at the 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F receptors, while antagonizing the 5-HT2A, 5-HT2B, and 5-HT2C receptors. It has also been...
    10 KB (952 words) - 12:15, 25 July 2023
  • Thumbnail for SB-649,915
    SB-649,915 (category 5-HT1 antagonists)
    SB-649,915 is a serotonin reuptake inhibitor and 5-HT1A and 5-HT1B receptor antagonist which is being investigated for its antidepressant effects. Relative...
    3 KB (131 words) - 23:23, 28 November 2022
  • Thumbnail for 5-HT1F receptor
    5-n-Butyryloxy-DMT: >60-fold selectivity versus 5-HT1E receptor BRL-54443 - mixed 5-HT1E/1F agonist Eletriptan - mixed 5-HT1B/1D/1E/1F/2B/7 agonist LY-334,370 - as...
    9 KB (1,053 words) - 15:17, 26 November 2023
  • Thumbnail for RU-24,969
    RU-24,969 (category 5-HT1B agonists)
    It is a selective agonist at the 5-HT1A and 5-HT1B receptors, with preference for the latter. As with other 5-HT1B agonists such as CP-94,253, RU-24...
    2 KB (164 words) - 21:23, 1 March 2024