• Thumbnail for Acetylcholine receptor
    An acetylcholine receptor (abbreviated AChR) or a cholinergic receptor is an integral membrane protein that responds to the binding of acetylcholine, a...
    13 KB (1,300 words) - 18:52, 8 May 2024
  • Thumbnail for Muscarinic acetylcholine receptor
    Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain...
    31 KB (2,714 words) - 18:27, 22 September 2024
  • Thumbnail for Nicotinic acetylcholine receptor
    Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond...
    48 KB (4,787 words) - 14:08, 24 September 2024
  • Thumbnail for Acetylcholine
    nicotine are derived from its effects on nicotinic acetylcholine receptors in the brain. Acetylcholine is a choline molecule that has been acetylated at...
    41 KB (4,374 words) - 04:43, 17 September 2024
  • Thumbnail for Muscarinic acetylcholine receptor M1
    The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by...
    22 KB (2,221 words) - 04:29, 10 August 2024
  • Thumbnail for Muscarinic acetylcholine receptor M3
    muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded...
    16 KB (1,761 words) - 18:13, 7 June 2024
  • Thumbnail for Muscarinic acetylcholine receptor M4
    The muscarinic acetylcholine receptor M4, also known as the cholinergic receptor, muscarinic 4 (CHRM4), is a protein that, in humans, is encoded by the...
    16 KB (1,853 words) - 03:12, 24 November 2022
  • binding of ACh to muscarinic acetylcholine receptors; such agents do not antagonize the binding at nicotinic acetylcholine receptors at the neuromuscular junction...
    25 KB (2,388 words) - 05:24, 21 July 2024
  • Thumbnail for Muscarinic acetylcholine receptor M2
    The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans...
    19 KB (2,091 words) - 17:29, 25 September 2024
  • Thumbnail for Alpha-7 nicotinic receptor
    The alpha-7 nicotinic receptor, also known as the α7 receptor, is a type of nicotinic acetylcholine receptor implicated in long-term memory, consisting...
    26 KB (2,626 words) - 17:23, 19 June 2024
  • nicotinic or muscarinic receptors (thus mimicking acetylcholine), or indirectly by inhibiting cholinesterase, promoting acetylcholine release, or other mechanisms...
    7 KB (618 words) - 06:38, 29 April 2024
  • nicotinic agonist is a drug that mimics the action of acetylcholine (ACh) at nicotinic acetylcholine receptors (nAChRs). The nAChR is named for its affinity for...
    42 KB (4,258 words) - 12:55, 5 September 2024
  • The alpha-4 beta-2 nicotinic receptor, also known as the α4β2 receptor, is a type of nicotinic acetylcholine receptor implicated in learning, consisting...
    16 KB (1,639 words) - 00:34, 17 July 2024
  • Thumbnail for Neuromuscular junction
    release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs)...
    35 KB (4,084 words) - 00:41, 11 September 2024
  • Thumbnail for Muscarinic antagonist
    receptor antagonist (MRA), also called an antimuscarinic, is a type of anticholinergic agent that blocks the activity of the muscarinic acetylcholine...
    40 KB (1,998 words) - 10:32, 22 May 2024
  • Thumbnail for Muscarinic acetylcholine receptor M5
    The human muscarinic acetylcholine receptor M5, encoded by the CHRM5 gene, is a member of the G protein-coupled receptor superfamily of integral membrane...
    13 KB (1,508 words) - 12:25, 16 January 2024
  • Thumbnail for Muscarinic agonist
    agent that activates the activity of the muscarinic acetylcholine receptor. The muscarinic receptor has different subtypes, labelled M1-M5, allowing for...
    9 KB (844 words) - 07:33, 30 September 2024
  • Thumbnail for Xanomeline
    Xanomeline (LY-246,708; Lumeron, Memcor) is a small molecule muscarinic acetylcholine receptor agonist that was first synthesized in a collaboration between Eli...
    15 KB (1,419 words) - 13:30, 30 September 2024
  • nicotinic receptor, also known as the α3β4 receptor and the ganglion-type nicotinic receptor, is a type of nicotinic acetylcholine receptor, consisting...
    12 KB (1,100 words) - 23:20, 16 July 2024
  • Thumbnail for Bronchospasm
    and Ipratropium bromide (all of which act as receptor antagonists of muscarinic acetylcholine receptors) are effective for treating asthma and COPD-related...
    7 KB (718 words) - 00:07, 22 January 2024
  • Thumbnail for Cholinergic
    releasing acetylcholine, or butyrylcholine ("indirect-acting"), or mimicking their behaviours at one or more of the body's acetylcholine receptor ("direct-acting")...
    9 KB (972 words) - 03:17, 10 September 2024
  • muscarinic acetylcholine receptor positive allosteric modulator. Cobenfy (xanomeline/trospium) – combined M1 and M4 muscarinic acetylcholine receptor agonist...
    10 KB (755 words) - 10:41, 29 September 2024
  • Thumbnail for Xanomeline/trospium chloride
    LA, Levey AI (2004). "Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus". Acetylcholine in the Cerebral Cortex. Progress in...
    17 KB (1,507 words) - 16:08, 30 September 2024
  • Thumbnail for Neuromuscular-blocking drug
    This is accomplished via their action on the post-synaptic acetylcholine (Nm) receptors. In clinical use, neuromuscular block is used adjunctively to...
    60 KB (6,864 words) - 05:14, 1 August 2024
  • Thumbnail for Cell surface receptor
    electric signal which alters the cell excitability. The acetylcholine receptor is a receptor linked to a cation channel. The protein consists of four...
    21 KB (2,456 words) - 22:14, 21 November 2023
  • Thumbnail for Muscarine
    up to 1.6%. Muscarine is a selective agonist of the muscarinic acetylcholine receptors. The name muscarine derives from that of Amanita muscaria, from...
    18 KB (1,882 words) - 01:40, 28 June 2024
  • Thumbnail for Parasympathetic nervous system
    Sympathetic nervous system Acetylcholine Choline Cholinergic receptor Nicotinic acetylcholine receptor Muscarinic acetylcholine receptor Langley, John Newport...
    31 KB (3,918 words) - 01:46, 17 September 2024
  • Thumbnail for Acetylcholinesterase inhibitor
    autonomic ganglia and neuromuscular junctions, which are rich in acetylcholine receptors. Acetylcholinesterase inhibitors are one of two types of cholinesterase...
    26 KB (2,387 words) - 03:29, 21 August 2024
  • Thumbnail for Myasthenia gravis
    which results from antibodies that block or destroy nicotinic acetylcholine receptors (AChR) at the junction between the nerve and muscle. This prevents...
    84 KB (8,872 words) - 10:43, 13 September 2024
  • Thumbnail for Cotinine
    cotinine binds to, activates, and desensitizes neuronal nicotinic acetylcholine receptors, though at much lower potency in comparison. It has demonstrated...
    16 KB (1,727 words) - 08:02, 20 February 2024