Adenylate cyclase (EC 4.6.1.1, also commonly known as adenyl cyclase and adenylyl cyclase, abbreviated AC) is an enzyme with systematic name ATP diphosphate-lyase...
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Soluble adenylyl cyclase (sAC) is a regulatory cytosolic enzyme present in almost every cell. sAC is a source of cyclic adenosine 3’,5’ monophosphate (cAMP)...
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Photoactivated adenylyl cyclase (PAC) is a protein consisting of an adenylyl cyclase enzyme domain directly linked to a BLUF (blue light receptor using...
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of molecular biology, the cAMP-dependent pathway, also known as the adenylyl cyclase pathway, is a G protein-coupled receptor-triggered signaling cascade...
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S2CID 5739004. Waschek JA (2002). "Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration"...
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of adenylyl cyclase and its activity. Adenylyl cyclase plays an essential role in cognition. Neurofibromin's role in the activity of adenylyl cyclase explains...
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reaction to form a cyclic compound. Important cyclase enzymes include: Adenylyl cyclase, which forms cyclic AMP from adenosine triphosphate (EC 4.6.1.1) ADCY1...
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and stimulating cone photoreceptor death. Adenylyl cyclase Cyclic guanosine monophosphate Guanylyl cyclase activator (protein) Martin, Emil; Berka, Vladimir;...
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protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase. Gsα is a GTPase that functions as a cellular signaling protein. Gsα...
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subunit Gs-α, a key component of G protein-coupled receptor-regulated adenylyl cyclase signal transduction pathways. GNAS stands for Guanine Nucleotide binding...
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dissociates from the G protein, and associates with adenylyl cyclase. This causes the inactivation of adenylyl cyclase, resulting in a decrease of cAMP produced...
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nucleotidyl cyclases, such that production of cAMP is catalyzed by adenylyl cyclase and production of cGMP is catalyzed by guanylyl cyclase. Adenylyl cyclase has...
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study and research of cell physiology. Forskolin activates the enzyme adenylyl cyclase and increases intracellular levels of cAMP. cAMP is an important second...
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Signalling via Gαs activation of adenylyl cyclase. 5-HT5A 251.2 Memory consolidation. Signals via Gi/o inhibition of adenylyl cyclase. 5-HT6 98.41 Cognition (antagonists...
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Adenylyl cyclase type 6 is an enzyme that in humans is encoded by the ADCY6 gene. This gene encodes adenylyl cyclase 6, which is a membrane-associated...
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flukes). Bithionol has been shown to be a potent inhibitor of soluble adenylyl cyclase, an intracellular enzyme important in the catalysis of adenosine triphosphate...
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Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene. The protein encoded by this gene is related to the Saccharomyces...
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separates from Gβ𝛾 and interacts with the transmembrane protein adenylyl cyclase. Adenylyl cyclase catalyzes the conversion of ATP to cAMP. cAMP binds to protein...
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are inhibited with an antagonist, ethanol consumption is reduced. Adenylyl cyclase (AC) plays a role in ethanol induced signaling pathways. Acute ethanol...
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The cyclic AMP is generated by the oocyte by adenylyl cyclase in the oocyte membrane. The adenylyl cyclase is kept active by a constitutively active G-protein-coupled...
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synergistic increase in cAMP is mediated by and dependent on rutabaga adenylyl cyclase (rut AC), which is sensitive to both calcium (which results from voltage-gated...
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increase the breakdown of lipids in obese patients. β1 agonists stimulate adenylyl cyclase activity and opening of calcium channel (cardiac stimulants; used to...
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protein Gsα. D1 is also coupled to Golf. Gsα subsequently activates adenylyl cyclase, increasing the intracellular concentration of the second messenger...
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Adenylyl cyclase-associated protein 2 is an enzyme that in humans is encoded by the CAP2 gene. This gene was identified by its similarity to the gene for...
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cannabinoids causes a decrease in cAMP concentration by inhibition of adenylyl cyclase and a rise in the concentration of mitogen-activated protein kinase...
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proteins primarily inhibit the cAMP dependent pathway by inhibiting adenylyl cyclase activity, decreasing the production of cAMP from ATP, which, in turn...
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on the cell surface. Cyclic AMP is formed from ATP by the enzymes adenylyl cyclase. In 1970 Martin Rodbell found that hormones did not directly influence...
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Inhibiting the release of thyroid-stimulating hormone (TSH) Inhibiting adenylyl cyclase in parietal cells Inhibiting the release of prolactin (PRL) Somatostatin...
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Adenylyl cyclase type 2 is an enzyme typically expressed in the brain of humans, that is encoded by the ADCY2 gene. It belongs to the adenylyl cyclase...
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receptor belongs to the class of G-Protein coupled receptors that inhibit adenylyl cyclase, therefore leading to decreased cyclic adenosine monophosphate (cAMP)...
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