• Thumbnail for Aldol reaction
    The aldol reaction (aldol addition) is a reaction in organic chemistry that combines two carbonyl compounds (e.g. aldehydes or ketones) to form a new...
    38 KB (4,019 words) - 23:43, 30 July 2024
  • Thumbnail for Aldol condensation
    An aldol condensation is a condensation reaction in organic chemistry in which two carbonyl moieties (of aldehydes or ketones) react to form a β-hydroxyaldehyde...
    17 KB (1,679 words) - 06:32, 22 March 2024
  • Thumbnail for Aldol
    bond-formation reaction, giving them wide applicability as a precursor for a variety of other compounds. Aldols are usually synthesized from an aldol addition...
    5 KB (515 words) - 14:28, 4 August 2024
  • Thumbnail for Mukaiyama aldol addition
    In organic chemistry, the Mukaiyama aldol addition is an organic reaction and a type of aldol reaction between a silyl enol ether (R2C=CR−O−Si(CH3)3) and...
    9 KB (958 words) - 06:34, 11 February 2024
  • In organic chemistry, aldol reactions are acid- or base-catalyzed reactions of aldehydes or ketones. Aldol addition or aldolization refers to the addition...
    9 KB (957 words) - 09:12, 30 April 2024
  • and Barbas-List reactions in organic chemistry are a family of proline-catalysed asymmetric aldol reactions. In the 1970s, two research groups...
    22 KB (2,633 words) - 04:33, 13 April 2024
  • Thumbnail for Multiple Michael/aldol reaction
    Michael/aldol reaction (or domino Michael/aldol reaction) is a consecutive series of reactions composed of either Michael addition reactions or aldol reactions...
    3 KB (338 words) - 05:04, 15 August 2023
  • The Aldol–Tishchenko reaction is a tandem reaction involving an aldol reaction and a Tishchenko reaction. In organic synthesis, it is a method to convert...
    2 KB (160 words) - 18:47, 7 July 2024
  • Thumbnail for Chiral auxiliary
    stereoselective transformations, including aldol reactions, alkylation reactions, and Diels-Alder reactions. The oxazolidinones are substituted at the...
    34 KB (3,692 words) - 20:40, 22 July 2024
  • transformations termed Tandem Michael-aldol reactions, that sequentially combine Michael addition and aldol reaction into a single reaction. As is the case with Robinson...
    15 KB (1,743 words) - 22:55, 18 August 2024
  • active substrate; the reaction provides gramine derivatives. The Mannich reaction can be considered to involve a mixed-aldol reaction, dehydration of the...
    10 KB (1,013 words) - 10:44, 2 September 2024
  • The reaction is catalyzed by a base and a divalent metal such as calcium. The intermediary steps taking place are aldol reactions, reverse aldol reactions...
    6 KB (646 words) - 13:18, 22 July 2024
  • Thumbnail for Allylic strain
    oxazolidinone. There is another aspect of aldol reaction that is influenced by the allylic strain. On the second aldol reaction, the product which is a 1,3 dicarbonyl...
    21 KB (2,466 words) - 08:33, 1 September 2023
  • followed by the elimination of water in an E1cB dehydration reaction. Aldol reactions are a key reaction in organic chemistry because they provide a means of...
    17 KB (2,146 words) - 20:27, 22 July 2024
  • Thumbnail for Modified aldol tandem reaction
    Modified aldol tandem reaction is a sequential chemical transformation that combines aldol reaction with other chemical reactions that generate enolates...
    3 KB (370 words) - 21:09, 2 September 2023
  • Thumbnail for Alexander Borodin
    nucleophilic substitution, as well as being the co-discoverer of the aldol reaction. Borodin was a promoter of education in Russia and founded the School...
    25 KB (2,686 words) - 03:54, 14 July 2024
  • components of an aldol reaction are combined with the asymmetric catalyst S-proline in a ball mill in a mechanosynthesis. The reaction product has 97%...
    3 KB (379 words) - 17:47, 5 February 2024
  • Thumbnail for Dynamic kinetic resolution in asymmetric synthesis
    aldol reaction in tandem with dynamic kinetic resolution to obtain a high enantioselective reaction. In this reaction proline catalyzes the reaction through...
    13 KB (1,466 words) - 19:47, 20 April 2024
  • Self-condensation (category Condensation reactions)
    organic reaction in which a chemical compound containing a carbonyl group (C=O) acts both as the electrophile and the nucleophile in an aldol condensation...
    4 KB (488 words) - 21:50, 23 October 2023
  • Thumbnail for Α,β-Unsaturated carbonyl compound
    Unsaturated carbonyls can be prepared in the laboratory in an aldol reaction and in the Perkin reaction. α,β-Unsaturated carbonyl compounds can be subclassified...
    10 KB (1,119 words) - 23:33, 23 March 2024
  • Thumbnail for Darzens reaction
    bond. These two steps are similar to a base-catalyzed aldol reaction. The oxygen anion in this aldol-like product then SN2 attacks on the formerly-nucleophilic...
    7 KB (717 words) - 13:38, 27 December 2023
  • Thumbnail for Enolate
    Enolate (category Organic reactions)
    (LDA). Often, as in conventional Claisen condensations, Mannich reactions, and aldol condensations, enolates are generated in low concentrations with...
    21 KB (2,467 words) - 22:07, 14 August 2024
  • Thumbnail for Oxocarbenium
    Oxocarbenium (category Organic reactions)
    and enantioselective acetate aldol addition reactions. The oxocarbenium ion is used as an electrophile in the reaction. When the methyl group increases...
    18 KB (2,170 words) - 20:29, 22 July 2024
  • Thumbnail for Fructose-bisphosphate aldolase
    often just aldolase, is an enzyme catalyzing a reversible reaction that splits the aldol, fructose 1,6-bisphosphate, into the triose phosphates dihydroxyacetone...
    14 KB (1,622 words) - 14:06, 26 August 2023
  • acid (BLA) catalyzes a number of diene-aldehyde cycloaddition reactions. In the aldol reaction, the diastereoselectivity of the product is often dictated...
    11 KB (1,242 words) - 23:24, 12 November 2023
  • Thumbnail for Stork enamine alkylation
    beta-unsaturated aldehyde or ketone hydrolysis of the enamine back to a ketone The reaction also applies to acyl halides as electrophiles, which results in the formation...
    3 KB (404 words) - 10:57, 12 February 2024
  • Thumbnail for Organozinc chemistry
    after protonation. The benefits of the Reformatsky reaction over the conventional aldol reaction protocols is the following: Allows for exceedingly derivatized...
    33 KB (3,394 words) - 06:05, 9 December 2023
  • Thumbnail for Nitro-Mannich reaction
    carbon-carbon bond forming reactions in organic chemistry, including the aldol reaction, Henry reaction (nitro-aldol reaction) and Mannich reaction. Although extensive...
    25 KB (2,892 words) - 06:56, 29 April 2022
  • Thumbnail for Teruaki Mukaiyama
    the Mitsunobu reaction. The aldol reaction is an essential tool for synthetic chemists. At its simplest, the aldol reaction involves two carbonyl compounds...
    18 KB (2,170 words) - 02:55, 14 September 2024
  • deprotonation there, leading to enolates and possible aldol reactions. Under ideal conditions the reaction produces 50% of both the alcohol and the carboxylic...
    8 KB (930 words) - 13:46, 26 August 2024