Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β)...
60 KB (6,536 words) - 06:58, 4 November 2024
Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with...
44 KB (4,830 words) - 18:56, 11 August 2024
Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the...
18 KB (1,768 words) - 14:27, 21 August 2024
Amyloidosis (redirect from Amyloid degeneration)
Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs...
55 KB (5,423 words) - 03:20, 19 October 2024
Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of amyloid beta (Aβ) protein that present...
31 KB (3,371 words) - 18:54, 31 October 2024
In mycology a tissue or feature is said to be amyloid if it has a positive amyloid reaction when subjected to a crude chemical test using iodine as an...
8 KB (1,449 words) - 02:35, 8 October 2024
up amyloid in Wiktionary, the free dictionary. An amyloid is any of certain insoluble fibrous protein aggregates. Amyloid may also refer to: Amyloid (mycology)...
494 bytes (90 words) - 11:42, 22 July 2015
Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions...
50 KB (5,683 words) - 05:16, 29 June 2024
Amylin (redirect from Pro-islet amyloid polypeptide)
Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone. It is co-secreted with insulin from the pancreatic β-cells in the ratio...
33 KB (4,044 words) - 20:39, 24 August 2024
Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are...
7 KB (742 words) - 05:34, 16 October 2024
accumulation of malformed protein deposits in the cerebral cortex, called amyloid plaques and neurofibrillary tangles. These misfolded protein aggregates...
186 KB (19,745 words) - 14:15, 7 November 2024
AL amyloidosis (redirect from Amyloid light chain)
Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. The disease is caused when a...
16 KB (1,638 words) - 20:43, 24 September 2024
cellulose, "amyloid" actually is rich in protein. Subsequent research has shown that many different proteins can form amyloid, and that all amyloids show birefringence...
62 KB (4,598 words) - 21:08, 10 September 2024
Amyloid cardiomyopathy (stiff heart syndrome) is a condition resulting in the death of part of the myocardium (heart muscle). It is associated with the...
7 KB (514 words) - 15:39, 12 October 2024
Sylvain Lesné (redirect from Amyloid beta star 56)
is the primary author of a controversial 2006 Nature paper, "A specific amyloid-β protein assembly in the brain impairs memory". Lesné's work in the 2006...
35 KB (3,538 words) - 18:44, 29 August 2024
Familial amyloid polyneuropathy, also called transthyretin-related hereditary amyloidosis, transthyretin amyloidosis abbreviated also as ATTR (hereditary...
14 KB (1,486 words) - 16:53, 7 February 2024
Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease...
10 KB (780 words) - 07:19, 3 August 2024
Lecanemab (category Anti-amyloid monoclonal antibodies)
medication used for the treatment of Alzheimer's disease. Lecanemab is an amyloid beta-directed antibody. It is given via intravenous infusion to patients...
28 KB (2,480 words) - 10:45, 23 September 2024
Amyloid purpura is a condition marked by bleeding under the skin (purpura) in some individuals with amyloidosis. Its cause is unknown, but coagulation...
3 KB (258 words) - 01:42, 18 June 2024
Biochemistry of Alzheimer's disease (redirect from Amyloid hypothesis)
disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain. Amyloid beta is a short peptide that is an abnormal proteolytic...
65 KB (7,761 words) - 09:06, 10 September 2024
Familial amyloid cardiomyopathy (FAC), or transthyretin amyloid cardiomyopathy (ATTR-CM) results from the aggregation and deposition of mutant and wild-type...
7 KB (791 words) - 05:23, 19 October 2024
protein has been identified as part of the enzymatic complex that cleaves amyloid-beta peptide from APP. The gene contains 14 exons, and the coding portion...
34 KB (3,741 words) - 12:37, 18 October 2024
Anti-amyloid drugs, also known as anti-amyloid antibodies (AAA), are a class of monoclonal antibodies developed to treat Alzheimer's disease. The first...
8 KB (2,404 words) - 12:33, 27 September 2024
presence of amyloid plaques and neurofibrillary tangles. Plaques are made up of small peptides, typically 39–43 amino acids in length, called amyloid beta (also...
63 KB (6,940 words) - 13:34, 1 November 2024
amyloidosis where there is depositing of the protein amyloid in the cardiac muscle and surrounding tissues. Amyloid, a misfolded and insoluble protein, can become...
30 KB (3,354 words) - 02:30, 21 June 2024
Amyloid: the Journal of Protein Folding Disorders is a peer-reviewed scientific journal that publishes original research and review articles on all aspects...
3 KB (194 words) - 11:43, 26 April 2023
The familial amyloid neuropathies (or familial amyloidotic neuropathies, neuropathic heredofamilial amyloidosis, familial amyloid polyneuropathy) are a...
6 KB (505 words) - 14:56, 27 October 2023
associated with amyloid diseases including wild-type transthyretin amyloidosis, hereditary transthyretin amyloidosis, familial amyloid polyneuropathy (FAP)...
20 KB (2,382 words) - 16:13, 22 January 2024
Isolated atrial amyloidosis (redirect from Senile amyloid of atria of heart)
Isolated atrial amyloidosis is a form of amyloidosis affecting the atria of the heart.[citation needed] It is associated with accumulation of the protein...
1 KB (62 words) - 05:07, 3 November 2023
can form a fibril, leading to abnormal protein aggregates called amyloids. These amyloids accumulate in infected tissue, causing damage and cell death. The...
99 KB (10,732 words) - 13:28, 2 November 2024