• required for transport (ESCRT) machinery is made up of cytosolic protein complexes, known as ESCRT-0, ESCRT-I, ESCRT-II, and ESCRT-III. Together with a number...
    24 KB (2,948 words) - 22:42, 26 September 2024
  • Thumbnail for Exosome (vesicle)
    required for transport (ESCRT) dependent pathway. ESCRT machinery mediates the ubiquitinated pathway consisting of protein complexes; ESCRT-0, -I, -II, -III...
    69 KB (7,390 words) - 13:39, 26 November 2024
  • Thumbnail for TSG101
    tumorigenesis and/or progression. The main role of TSG101 is to participate in ESCRT pathway. This pathway facilitates reverse topology budding and formation...
    16 KB (1,970 words) - 00:17, 14 August 2024
  • Thumbnail for Henipavirus
    pro-inflammatory response and is also known to promote the viral budding process via a ESCRT-dependent pathway. Cell receptor ephrin-B2, which is located on epithelial...
    23 KB (2,516 words) - 10:57, 18 June 2024
  • Thumbnail for Archaea
    Cdv fulfills a similar role. This machinery is related to the eukaryotic ESCRT-III machinery which, while best known for its role in cell sorting, also...
    159 KB (16,791 words) - 18:57, 1 January 2025
  • Thumbnail for Vps37b, escrt-i subunit
    VPS37B, ESCRT-I subunit is a protein that in humans is encoded by the VPS37B gene. GRCh38: Ensembl release 89: ENSG00000139722 – Ensembl, May 2017 GRCm38:...
    769 bytes (114 words) - 23:33, 8 November 2024
  • Thumbnail for Wesley Sundquist
    membrane remodeling by the Endosomal Sorting Complexes Required for Transport (ESCRT) pathway. Sundquist was born in Saint Paul, Minnesota on September 11, 1959...
    11 KB (1,043 words) - 21:08, 9 December 2024
  • nor the FtsZ mechanism. They use a primitive version of the eukaryotic ESCRT-III system (also known as Cdv) to manipulate the membrane into separating...
    20 KB (2,236 words) - 18:20, 31 December 2024
  • Thumbnail for Nuclear envelope
    process dependent on "endosomal sorting complexes required for transport" (ESCRT) made up of cytosolic protein complexes. During nuclear membrane rupture...
    18 KB (2,035 words) - 20:50, 20 October 2024
  • Thumbnail for Endosome
    addition of ubiquitin. The endosomal sorting complexes required for transport (ESCRTs) recognise this ubiquitin and sort the protein into the forming lumenal...
    22 KB (2,647 words) - 07:14, 29 May 2024
  • Thumbnail for Galectin
    cellular response to membrane damage are expanding, e.g. Galectin-3 recruits ESCRTs to damaged lysosomes so that lysosomes can be repaired. This occurs before...
    34 KB (3,864 words) - 01:49, 22 June 2024
  • Thumbnail for Cytoskeleton
    tubulin-like (often FtsZ-ring) proteins and sometimes (Thermoproteota) ESCRT-III, which in eukaryotes still has a role in the last step of division....
    45 KB (5,122 words) - 19:13, 4 December 2024
  • Thumbnail for Asgard (Archaea)
    signature proteins, including novel GTPases, membrane-remodelling proteins like ESCRT and SNF7, a ubiquitin modifier system, and N-glycosylation pathway homologs...
    37 KB (2,984 words) - 12:37, 5 December 2024
  • Thumbnail for Hepatitis C virus
    reticulum through the endosomal sorting complex required for transport (ESCRT) pathway. This pathway is normally utilized to bud vesicles out of the cell...
    54 KB (6,627 words) - 09:27, 2 December 2024
  • Thumbnail for Mumps virus
    endosomal sorting complex required for transport (ESCRT) structures at the site of budding. There, ESCRT proteins form into concentric spirals and push the...
    21 KB (2,850 words) - 11:40, 17 December 2024
  • Thumbnail for AAA proteins
    involves the sequential action of three multiprotein complexes, ESCRT I to III (ESCRT standing for 'endosomal sorting complexes required for transport')...
    12 KB (1,352 words) - 03:31, 10 November 2024
  • Thumbnail for Polydactyly
    Anderson, Kathryn V.; Lacy, Elizabeth; Selleri, Licia (October 2014). "ESCRT-II/Vps25 Constrains Digit Number by Endosome-Mediated Selective Modulation...
    63 KB (7,313 words) - 09:24, 2 January 2025
  • Thumbnail for VPS37A
    It is a member of the endosomal sorting complex required for transport (ESCRT) system. A missense mutation (K382N) in VPS37A protein has been shown to...
    4 KB (543 words) - 05:28, 28 November 2023
  • Thumbnail for CHMP2A
    MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003...
    4 KB (564 words) - 07:53, 6 January 2024
  • Thumbnail for VPS24
    along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional...
    8 KB (1,026 words) - 21:54, 3 March 2023
  • Thumbnail for Two-domain system
    complexes, required for transport (ESCRT III), involved in eukaryotic cell division, are found in all TACK groups. The ESCRT-III-like proteins constitute the...
    42 KB (4,629 words) - 15:28, 9 December 2024
  • Thumbnail for SNF8
    is a protein that in humans is encoded by the SNF8 gene. It is a part of ESCRT-II complex. GRCh38: Ensembl release 89: ENSG00000159210 – Ensembl, May 2017...
    4 KB (506 words) - 22:57, 26 September 2024
  • Thumbnail for Kaposi's sarcoma-associated herpesvirus
    Jawed; Gjyshi, Olsi; Bottero, Virginie; Chandran, Bala (April 2016). "ESCRT-0 Component Hrs Promotes Macropinocytosis of Kaposi's Sarcoma-Associated...
    44 KB (5,239 words) - 19:23, 14 September 2024
  • Thumbnail for VPS25
    the endosome-associated complex ESCRT-II (Endosomal Sorting Complexes Required for Transport protein II). ESCRT (ESCRT-I, -II, -III) complexes orchestrate...
    7 KB (816 words) - 02:26, 28 September 2024
  • Thumbnail for VPS28
    the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated protein. The two other subunits of ESCRT-I are...
    7 KB (906 words) - 06:51, 29 December 2023
  • Thumbnail for CHMP2B
    one of the endosomal sorting complexes required for transport (ESCRT) - specifically ESCRT-III - which are a series of complexes involved in cell membrane...
    8 KB (1,047 words) - 05:28, 24 December 2023
  • Thumbnail for Carol A. Carter
    signaling machinery to endosomal sorting complexes required for transport (ESCRT), thus stabilizing viral assembly at the budding site. She continued working...
    16 KB (1,746 words) - 06:47, 18 November 2024
  • acidocaldarius possess a mechanism of replication homologous to the eukaryotic ESCRT. Sulfolobus acidocaldarius is a facultative autotroph. When growing autotrophically...
    8 KB (956 words) - 23:39, 30 May 2023
  • Thumbnail for Proteasome
    also use the proteasome to control cell cycle, specifically by controlling ESCRT-III-mediated cell division. In plants, signaling by auxins, or phytohormones...
    105 KB (12,670 words) - 08:02, 23 August 2024
  • Thumbnail for Cytokinesis
    polymerization of the endosomal sorting complex required for transport III (ESCRT-III), which serves to physically constrict and separate the plasma membrane...
    28 KB (3,585 words) - 09:51, 18 August 2024