Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
17 KB (1,845 words) - 01:41, 9 October 2024
The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
8 KB (827 words) - 22:08, 3 December 2023
fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor...
25 KB (3,124 words) - 21:38, 18 August 2024
Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2...
14 KB (1,745 words) - 09:02, 15 July 2024
via specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was...
22 KB (2,698 words) - 17:05, 16 July 2024
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
44 KB (5,003 words) - 07:11, 15 October 2024
Fibroblast growth factor 23 (FGF-23) is a protein and member of the fibroblast growth factor (FGF) family which participates in the regulation of phosphate...
16 KB (1,840 words) - 07:12, 2 November 2024
growth factor (FGF) Fibroblast growth factor 1(FGF1) Fibroblast growth factor 2(FGF2) Fibroblast growth factor 3(FGF3) Fibroblast growth factor 4(FGF4)...
10 KB (1,131 words) - 19:14, 31 March 2024
Fibroblast growth factor receptor 4 (FGFR-4) is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as CD334 (cluster...
10 KB (1,291 words) - 09:08, 15 July 2024
epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
60 KB (6,879 words) - 14:26, 16 July 2024
Fibroblast growth factor 21 (FGF-21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
24 KB (3,038 words) - 23:40, 29 November 2024
Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1...
20 KB (2,311 words) - 22:01, 16 July 2024
Fibroblast growth factor 8 (FGF-8) is a protein that in humans is encoded by the FGF8 gene. The protein encoded by this gene is a member of the fibroblast...
17 KB (2,175 words) - 03:31, 24 December 2023
Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this gene is a member of the...
6 KB (842 words) - 01:10, 27 January 2024
cell culture system, rat kidney fibroblasts. Application of the transforming growth factors to normal rat kidney fibroblasts induces the cultured cells to...
6 KB (596 words) - 05:15, 1 January 2024
fibroblast growth factor (FGF) activates a signaling pathway that positively regulates the PDGF receptors in OPCs. PDGF was one of the first growth factors...
24 KB (2,882 words) - 16:31, 25 October 2024
natriuretic peptide receptor type B (NPR-B), which reduces the activity of fibroblast growth factor receptor 3 (FGFR3). FGFR3 is a receptor that normally down-regulates...
19 KB (1,329 words) - 15:13, 7 September 2024
is known as mechano-growth factor (MGF). Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD),...
35 KB (4,575 words) - 06:26, 15 December 2024
Hypochondroplasia (category Growth disorders)
disorder caused by an autosomal dominant genetic defect in the fibroblast growth factor receptor 3 gene (FGFR3) that results in a disproportionately short stature...
7 KB (549 words) - 14:29, 27 October 2023
Achondroplasia (category Growth disorders)
immunodeficiency. Achondroplasia is caused by a mutation in the fibroblast growth factor receptor 3 (FGFR3) gene that results in its protein being overactive...
47 KB (4,420 words) - 00:20, 5 December 2024
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...
28 KB (3,078 words) - 07:46, 3 June 2024
epithelium. KGF is a small signaling molecule that binds to fibroblast growth factor receptor 2b (FGFR2b). For signalling to occur, a dimer is required...
2 KB (182 words) - 00:56, 11 June 2023
Paracrine signaling (redirect from Paracrine factor)
fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates...
46 KB (4,967 words) - 21:12, 7 July 2024
signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by platelets, and mesenchymal cells and acts as...
23 KB (2,617 words) - 23:17, 21 December 2024
Craniosynostosis (section Biomechanical factors)
found in the fibroblast growth factor receptor 3 (FGFR3) and TWIST genes. Fibroblast growth factor and fibroblast growth factor receptors regulate fetal...
71 KB (7,727 words) - 04:47, 31 October 2024
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different...
67 KB (8,184 words) - 18:33, 6 December 2024
on ovine chromosome 6, and involves the inactivation of fibroblast growth factor receptor 3. It has been compared to dwarfism in beef cattle. Afflicted...
6 KB (759 words) - 10:52, 20 August 2022
Thanatophoric dysplasia (category Cell surface receptor deficiencies)
needed] It can be associated with missense mutations in fibroblast growth factor receptor-3. It is inherited in an autosomal dominant manner. While the...
7 KB (792 words) - 00:05, 30 October 2024
Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
29 KB (3,354 words) - 17:01, 9 December 2023
insulin-like growth factor-2 (IGF-2), transforming growth factor beta (TGF-β), fibroblast growth factors (FGFs), platelet-derived growth factor (PDGF), parathyroid...
17 KB (2,027 words) - 21:28, 21 December 2024