• Thumbnail for Haptoglobin
    Haptoglobin (abbreviated as Hp) is the protein that in humans is encoded by the HP gene. In blood plasma, haptoglobin binds with high affinity to free...
    26 KB (2,908 words) - 20:39, 21 November 2024
  • Thumbnail for CD163
    affinity scavenger receptor for the hemoglobin-haptoglobin complex and in the absence of haptoglobin - with lower affinity - for hemoglobin alone. It...
    18 KB (2,140 words) - 05:39, 26 March 2025
  • Thumbnail for Hemopexin
    detoxification. Hemopexin is different from haptoglobin, the latter always binds to free hemoglobin. (See Haptoglobin § Differentiation with hemopexin) Takahashi...
    22 KB (2,570 words) - 20:25, 2 October 2024
  • Thumbnail for Haptoglobin-related protein
    Haptoglobin-related protein (Hpr) is a serum protein that binds to haemoglobin of red blood cells and is present only in primates. It acts as a molecule...
    14 KB (1,609 words) - 17:37, 18 April 2024
  • the physiologic range of haptoglobin, the potential deleterious effects of free hemoglobin are prevented because haptoglobin will bind to "free hemoglobin"...
    10 KB (1,034 words) - 01:53, 19 August 2023
  • Thumbnail for Hemolytic anemia
    Free hemoglobin can bind to haptoglobin, and the complex is cleared from the circulation; thus, a decrease in haptoglobin can support a diagnosis of hemolytic...
    32 KB (3,563 words) - 19:37, 15 February 2025
  • Thumbnail for Hemoglobinemia
    hemoglobin is released and binds with haptoglobin. This causes haptoglobin levels to decrease. Once haptoglobin is saturated, free hemoglobin readily...
    7 KB (789 words) - 18:34, 22 October 2023
  • Zonulin (haptoglobin 2 precursor) is a protein that increases the permeability of tight junctions between cells of the wall of the digestive tract. It...
    4 KB (418 words) - 13:25, 11 April 2024
  • Thumbnail for Serum protein electrophoresis
    alpha-2 macroglobulin (AMG or A2M) and haptoglobin. There are typically low levels in haemolytic anaemia (haptoglobin is a suicide molecule which binds with...
    17 KB (2,213 words) - 11:38, 13 April 2025
  • hemoglobin from the ruptured red blood cells to form haptoglobin-hemoglobin complexes with haptoglobin, which will be internalized and degraded by hepatocytes...
    28 KB (3,023 words) - 17:23, 9 July 2024
  • Thumbnail for Trypanosoma brucei
    trypanosome haptoglobin-hemoglobin receptor (TbHpHbR). TLF-2 enters trypanosomes independently of TbHpHbR. TLF-1 uptake increases when haptoglobin level is...
    106 KB (12,738 words) - 20:03, 1 April 2025
  • into the bloodstream in excess of the binding capacity of haptoglobin. The function of haptoglobin is to bind to circulating hemoglobin, thereby reducing...
    1 KB (181 words) - 01:53, 21 September 2022
  • Thumbnail for Hemolysis
    production of bilirubin and depletion of plasma proteins, such as albumin, haptoglobin, and hemopexin, which may lead to jaundice. It may also lead to increased...
    29 KB (2,619 words) - 03:53, 21 February 2025
  • Thumbnail for Rhabdomyolysis
    accumulation of myoglobin in the kidney tubules. Normally, the blood protein haptoglobin binds circulating myoglobin and other heme-containing substances, but...
    49 KB (4,821 words) - 00:33, 30 January 2025
  • sitcom "HP" (song), a 2019 song by Maluma Horsepower, a unit of power Haptoglobin, a protein Hypersensitivity pneumonitis, a respiratory inflammation High...
    3 KB (492 words) - 19:03, 25 January 2025
  • Thumbnail for Acute-phase protein
    protein, complement factors, ferritin, ceruloplasmin, serum amyloid A and haptoglobin. Others give negative feedback on the inflammatory response, e.g. serpins...
    11 KB (1,096 words) - 14:00, 24 December 2023
  • Thumbnail for Hemolytic–uremic syndrome
    cells, and which is therefore a marker of cellular damage) decreased haptoglobin (indicative of the breakdown of red blood cells) anemia (low red blood...
    56 KB (5,764 words) - 03:14, 11 April 2025
  • hemoglobin are released, with the latter binding to serum bilirubin or haptoglobin. During the coagulation cascade, fibrin is deposited in the liver and...
    33 KB (3,742 words) - 22:30, 13 April 2025
  • Thumbnail for Hereditary spherocytosis
    processed in the liver. Haptoglobin (free): Decreased (normal range: 41–165 mg/dL). This is caused by hemoglobin binding to haptoglobin, thus making it no...
    31 KB (3,115 words) - 21:53, 3 January 2025
  • hemolysis; including elevated lactate dehydrogenase (LDH), decreased haptoglobin and elevated unconjugated bilirubin. Reticulocytosis, or an increase...
    26 KB (3,094 words) - 18:23, 8 October 2024
  • Alpha-1-fetoprotein alpha2-macroglobulin Gamma globulins Beta-2 microglobulin Haptoglobin Human Serum Albumin Ceruloplasmin Complement component 3 Complement component...
    6 KB (564 words) - 05:31, 16 April 2025
  • Thumbnail for Alpha globulin
    Orosomucoid (acid glycoprotein) Serum amyloid A Alpha 1-lipoprotein Protein HC Haptoglobin Alpha-2u globulin α2-macroglobulin Ceruloplasmin Thyroxine-binding globulin...
    1 KB (119 words) - 19:37, 23 October 2023
  • Thumbnail for Ovarian cancer
    cancer include CA19-9, CA72-4, CA15-3, immunosuppressive acidic protein, haptoglobin-alpha, OVX1, mesothelin, lysophosphatidic acid, osteopontin, and fibroblast...
    199 KB (21,252 words) - 06:47, 2 April 2025
  • Thumbnail for Monoclonal gammopathy
    of α1-antitrypsin and α1-acid glycoprotein. The α2 region is mostly haptoglobin, α2-macroglobulin, α2-antiplasmin, and ceruloplasmin. The β band consists...
    7 KB (684 words) - 06:22, 20 September 2023
  • Lovrien, she linked the 16q fragile site to the gene for haptoglobin. The mapping of haptoglobin to 16q was the second instance in which a human gene was...
    4 KB (394 words) - 11:49, 15 April 2025
  • proteins, such as antibodies directed against IgA or haptoglobin in people with IgA and haptoglobin deficiency, have been suggested to have a causal relationship...
    5 KB (588 words) - 15:35, 18 July 2024
  • Thumbnail for Bothrops jararaca
    and anemia worsened, with blood films showing fragmented red cells, haptoglobin consumption, increase in lactate dehydrogenase and progressive increase...
    12 KB (1,288 words) - 14:17, 29 October 2024
  • Thumbnail for Thrombotic microangiopathy
    hemolysis: increased unconjugated bilirubin, increased LDH, decreased haptoglobin negative Coombs test. Creatinine, urea, to follow renal function. ADAMSTS-13...
    11 KB (1,202 words) - 19:33, 12 February 2025
  • Glycated hemoglobin (HbA1c) < 50 years 3.6 5.0 % of Hb > 50 years 3.9 5.3 Haptoglobin < 50 years 0.35 1.9 g/L > 50 years 0.47 2.1 Hematocrit (Hct) Male 0.39...
    108 KB (6,105 words) - 10:44, 2 July 2024
  • Thumbnail for Ultrafiltration (kidney)
    freely, while larger plasma proteins, such as hemoglobin tetramers, haptoglobin bound hemoglobin and albumin have practically no permeability at all...
    4 KB (464 words) - 02:23, 12 December 2023