Haptoglobin (abbreviated as Hp) is the protein that in humans is encoded by the HP gene. In blood plasma, haptoglobin binds with high affinity to free...
26 KB (2,908 words) - 20:39, 21 November 2024
Haptoglobin-related protein (Hpr) is a serum protein that binds to haemoglobin of red blood cells and is present only in primates. It acts as a molecule...
14 KB (1,609 words) - 17:37, 18 April 2024
Hemolytic jaundice (section Haptoglobin testing)
hemoglobin from the ruptured red blood cells to form haptoglobin-hemoglobin complexes with haptoglobin, which will be internalized and degraded by hepatocytes...
28 KB (3,023 words) - 17:23, 9 July 2024
hemoglobin is released and binds with haptoglobin. This causes haptoglobin levels to decrease. Once haptoglobin is saturated, free hemoglobin readily...
7 KB (789 words) - 18:34, 22 October 2023
alpha-2 macroglobulin (AMG or A2M) and haptoglobin. There are typically low levels in haemolytic anaemia (haptoglobin is a suicide molecule which binds with...
17 KB (2,229 words) - 20:08, 6 February 2024
Hemopexin (section Relation to haptoglobin)
detoxification. Hemopexin is different from haptoglobin, the latter always binds to free hemoglobin. (See Haptoglobin § Differentiation with hemopexin) Takahashi...
22 KB (2,570 words) - 20:25, 2 October 2024
into the bloodstream in excess of the binding capacity of haptoglobin. The function of haptoglobin is to bind to circulating hemoglobin, thereby reducing...
1 KB (181 words) - 01:53, 21 September 2022
Free hemoglobin can bind to haptoglobin, and the complex is cleared from the circulation; thus, a decrease in haptoglobin can support a diagnosis of hemolytic...
32 KB (3,557 words) - 12:31, 9 September 2024
affinity scavenger receptor for the hemoglobin-haptoglobin complex and in the absence of haptoglobin - with lower affinity - for hemoglobin alone. It...
18 KB (2,166 words) - 04:31, 20 December 2024
the physiologic range of haptoglobin, the potential deleterious effects of free hemoglobin are prevented because haptoglobin will bind to "free hemoglobin"...
10 KB (1,034 words) - 01:53, 19 August 2023
Alpha-1-fetoprotein alpha2-macroglobulin Gamma globulins Beta-2 microglobulin Haptoglobin Human Serum Albumin Ceruloplasmin Complement component 3 Complement component...
6 KB (565 words) - 07:50, 7 June 2024
Zonulin (haptoglobin 2 precursor) is a protein that increases the permeability of tight junctions between cells of the wall of the digestive tract. It...
4 KB (418 words) - 13:25, 11 April 2024
production of bilirubin and depletion of plasma proteins, such as albumin, haptoglobin, and hemopexin, which may lead to jaundice. It may also lead to increased...
29 KB (2,689 words) - 01:43, 14 January 2024
protein, complement factors, ferritin, ceruloplasmin, serum amyloid A and haptoglobin. Others give negative feedback on the inflammatory response, e.g. serpins...
11 KB (1,096 words) - 14:00, 24 December 2023
Orosomucoid (acid glycoprotein) Serum amyloid A Alpha 1-lipoprotein Protein HC Haptoglobin Alpha-2u globulin α2-macroglobulin Ceruloplasmin Thyroxine-binding globulin...
1 KB (119 words) - 19:37, 23 October 2023
hemolysis; including elevated lactate dehydrogenase (LDH), decreased haptoglobin and elevated unconjugated bilirubin. Reticulocytosis, or an increase...
26 KB (3,094 words) - 18:23, 8 October 2024
trypanosome haptoglobin-hemoglobin receptor (TbHpHbR). TLF-2 enters trypanosomes independently of TbHpHbR. TLF-1 uptake increases when haptoglobin level is...
108 KB (12,588 words) - 23:27, 1 January 2025
accumulation of myoglobin in the kidney tubules. Normally, the blood protein haptoglobin binds circulating myoglobin and other heme-containing substances, but...
49 KB (4,819 words) - 07:18, 30 September 2024
and anemia worsened, with blood films showing fragmented red cells, haptoglobin consumption, increase in lactate dehydrogenase and progressive increase...
12 KB (1,288 words) - 14:17, 29 October 2024
of α1-antitrypsin and α1-acid glycoprotein. The α2 region is mostly haptoglobin, α2-macroglobulin, α2-antiplasmin, and ceruloplasmin. The β band consists...
7 KB (684 words) - 06:22, 20 September 2023
processed in the liver. Haptoglobin (free): Decreased (normal range: 41–165 mg/dL). This is caused by hemoglobin binding to haptoglobin, thus making it no...
31 KB (3,114 words) - 19:55, 15 October 2024
hemoglobin are released, with the latter binding to serum bilirubin or haptoglobin. During the coagulation cascade, fibrin is deposited in the liver and...
33 KB (3,744 words) - 07:18, 5 September 2024
cells, and which is therefore a marker of cellular damage) decreased haptoglobin (indicative of the breakdown of red blood cells) anemia (low red blood...
55 KB (5,686 words) - 19:10, 18 November 2024
sitcom "HP" (song), a 2019 song by Maluma Horsepower, a unit of power Haptoglobin, a protein Hypersensitivity pneumonitis, a respiratory inflammation High...
3 KB (485 words) - 04:45, 15 October 2024
dehydrogenase (elevated in hemolysis and a marker of hemolytic severity) Haptoglobin (decreased in hemolysis); A "direct antiglobulin test" (Coombs' test)...
38 KB (3,970 words) - 13:30, 31 October 2024
pathology. Platelet count, aspartate transaminase, alanine transaminase, and haptoglobin are usually unaffected and may be used to distinguish mirror syndrome...
7 KB (733 words) - 21:05, 14 August 2024
cancer include CA19-9, CA72-4, CA15-3, immunosuppressive acidic protein, haptoglobin-alpha, OVX1, mesothelin, lysophosphatidic acid, osteopontin, and fibroblast...
198 KB (21,235 words) - 09:05, 2 January 2025
freely, while larger plasma proteins, such as hemoglobin tetramers, haptoglobin bound hemoglobin and albumin have practically no permeability at all...
4 KB (464 words) - 02:23, 12 December 2023
MUC5B MUC6 MUC7 MUC8 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC20 Other Haptoglobin Intrinsic factor Orosomucoid Peptidoglycan Phytohaemagglutinin Ovomucin...
36 KB (4,018 words) - 18:24, 24 September 2024
proteins, such as antibodies directed against IgA or haptoglobin in people with IgA and haptoglobin deficiency, have been suggested to have a causal relationship...
5 KB (588 words) - 15:35, 18 July 2024