Interferons (IFNs, /ˌɪntərˈfɪərɒn/ IN-tər-FEER-on) are a group of signaling proteins made and released by host cells in response to the presence of several...

Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...

Pegylated interferon (PEG-IFN) is a class of medication that includes three different drugs as of 2012: Pegylated interferon-alpha-2a Pegylated interferon-alpha-2b...

Interferon gamma (IFNG or IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon...

Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...

Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by...

An interferon-stimulated gene (ISG) is a gene that can be expressed in response to stimulation by interferon. Interferons bind to receptors on the surface...

The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses...

Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon...

Interferon tau (IFNτ, IFNT) is a Type I interferon made of a single chain of amino acids. IFN-τ was first discovered in ruminants as the signal for the...

Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and...

Interferon regulatory factors (IRF) are proteins which regulate transcription of interferons (see regulation of gene expression). Interferon regulatory...

Interferon-induced transmembrane protein 2 is a protein that in humans is encoded by the IFITM2 gene. IFITM1 is a member of the IFITM family (Interferon-induced...

Interferon alpha-n3 (Alferon-N) is a medication consisting of purified natural human interferon alpha proteins used for the treatment of genital warts...

Interferon-γ release assays (IGRA) are medical tests used in the diagnosis of some infectious diseases, especially tuberculosis. Interferon-γ (IFN-γ)...

Interferon beta-1b is a cytokine in the interferon family used to treat the relapsing-remitting and secondary-progressive forms of multiple sclerosis (MS)...

signaling as immunomodulating agents. Cytokines include chemokines, interferons, interleukins, lymphokines, and tumour necrosis factors, but generally...

type of immune cell that are known to secrete large quantities of type 1 interferon (IFNs) in response to a viral infection. They circulate in the blood and...

The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...

Interferon-stimulated gene 15 (ISG15) is a 17 kDA secreted protein that in humans is encoded by the ISG15 gene. ISG15 is induced by type I interferon...

Pegylated interferon alfa-2a, sold under the brand name Pegasys among others, is medication used to treat hepatitis C and hepatitis B. For hepatitis C...

International Cytokine & Interferon Society (ICIS) is a non-profit organization composed of researchers of cytokines, interferons and chemokine cell biology...

The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon...

of interferon gamma and TNF.[citation needed] CD4+ T-helper cells may be differentiated into two main categories: TH1 cells which produce interferon gamma...

Interferon alfacon-1 is a recombinant synthetic type I interferon used for the treatment of hairy cell leukemia, malignant melanoma and AIDS-related Kaposi's...

Natalizumab and interferon beta-1a (Rebif) may reduce relapses compared to both placebo and interferon beta-1a (Avonex) while Interferon beta-1b (Betaseron)...

Recombinant feline interferon omega (RFeIFN-ω), sold under the brand name Virbagen Omega among others, is a recombinant version of a cat interferon alpha. It is...

In molecular biology, the interferon-inducible GTPase (IIGP) family of proteins is thought to play a role in intracellular defence. IIGP is predominantly...

where TB prevalence is high. These have been reviewed in detail. Interferon-γ (interferon-gamma) release assays (IGRAs) are 21st century tests for tuberculosis...

It binds to the type I interferon receptor, blocking the activity of type I interferons such as interferon-α and interferon-β.[medical citation needed]...