• Kallikreins are a subgroup of serine proteases, enzymes capable of cleaving peptide bonds in proteins. In humans, plasma kallikrein (encoded by KLKB1...
    11 KB (1,173 words) - 07:19, 30 October 2024
  • The kinin–kallikrein system or simply kinin system is a poorly understood hormonal system with limited available research. It consists of blood proteins...
    7 KB (855 words) - 03:08, 24 June 2024
  • Thumbnail for Prostate-specific antigen
    gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase...
    50 KB (5,683 words) - 05:06, 17 August 2024
  • Kallikrein 13 (EC 3.4.21.119, KLK13, kallikrein mK13, mGK-13, mK13, mKLK13, prorenin converting enzyme 1, PRECE-1, prorenin-converting enzyme, PRECE,...
    2 KB (270 words) - 14:38, 26 August 2023
  • Urinary kallikrein may refer to: Plasma kallikrein, an enzyme Renal tissue kallikrein, an enzyme This set index page lists enzyme articles associated...
    426 bytes (47 words) - 20:07, 4 February 2015
  • Thumbnail for Kallikrein-5
    Kallikrein-5, formerly known as stratum corneum tryptic enzyme (SCTE), is a serine protease expressed in the epidermis. In humans it is encoded by the...
    9 KB (1,115 words) - 21:12, 27 March 2024
  • Term ''kallikrein 7 may refer to: Stratum corneum chymotryptic enzyme, an enzyme class KLK7, a serine protease that in humans is encoded by the KLK7 gene...
    184 bytes (58 words) - 01:11, 29 December 2019
  • Thumbnail for Plasma kallikrein
    Plasma kallikrein (EC 3.4.21.34) is an enzyme that catalyses the following chemical reaction: Selective cleavage of some Arg- and Lys- bonds, including...
    13 KB (1,616 words) - 13:09, 2 November 2024
  • tissue kallikrein (EC 3.4.21.35, glandular kallikrein, pancreatic kallikrein, submandibular kallikrein, submaxillary kallikrein, kidney kallikrein, urinary...
    8 KB (857 words) - 03:47, 22 June 2024
  • Thumbnail for KLK2
    KLK2 (redirect from Kallikrein-2)
    Kallikrein-2 is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue. GRCh38: Ensembl release 89:...
    10 KB (1,089 words) - 18:53, 12 October 2024
  • Thumbnail for KLK6
    KLK6 (redirect from Kallikrein-6)
    Kallikrein-6 is a protein that in humans is encoded by the KLK6 gene. Kallikrein-6 is also referred to as neurosin, protease M, hK6, or zyme. It is a 223...
    16 KB (1,866 words) - 18:53, 12 October 2024
  • Recombinant human tissue kallikrein-1, also known as DM199, is an experimental drug that acts on the kallikrein-kinin system and is developed for diabetes...
    3 KB (237 words) - 11:39, 4 January 2024
  • Thumbnail for Hereditary angioedema
    prevent HAE attacks by inactivating the kallikrein B1 (KLKB1) gene, which encodes for prekallikrein, the kallikrein precursor protein. "Hereditary angioedema"...
    40 KB (4,207 words) - 16:26, 30 October 2024
  • Thumbnail for Desquamation
    granulosum produce corneodesmosome-degrading kallikrein family members, especially KLK1, KLK5, and KLK7. Kallikreins are serine proteases. They are packaged...
    9 KB (878 words) - 21:05, 24 July 2024
  • Thumbnail for Sebetralstat
    evaluated for the treatment of hereditary angioedema. It is a plasma kallikrein inhibitor. "Sebetralstat - KalVista Pharmaceuticals". AdisInsight. Springer...
    3 KB (93 words) - 20:27, 10 September 2024
  • Thumbnail for Saliva
    is not activated until entering the acidic environment of the stomach Kallikrein, an enzyme that proteolytically cleaves high-molecular-weight kininogen...
    25 KB (2,799 words) - 15:49, 3 September 2024
  • Thumbnail for Angioedema
    C1-esterase (aka: C1-inhibitor or C1INH), and continuous production of kallikrein, another process inhibited by C1INH. This serine protease inhibitor (serpin)...
    26 KB (2,990 words) - 03:42, 2 November 2024
  • Thumbnail for KLK4
    KLK4 (redirect from Kallikrein-4)
    Kallikrein-related peptidase 4 is a protein which in humans is encoded by the KLK4 gene. Kallikreins are a subgroup of serine proteases having diverse...
    11 KB (1,328 words) - 04:52, 24 December 2023
  • Thumbnail for Contact activation system
    proteases and HK is a non-enzymatic co-factor. The CAS can activate the kinin–kallikrein system and blood coagulation through its ability to activate multiple...
    12 KB (1,456 words) - 06:25, 22 May 2024
  • the kallikrein-kinin system. In: The Kinin System. Academic Press, San Diego, CA, 1997. Beraldo WT, Siqueira G, Heneine IF. Kallikrein and kallikrein inhibitor...
    4 KB (335 words) - 07:53, 26 February 2024
  • Kallikrein 8 (EC 3.4.21.118, KLK8, PRSS19, human kallikrein 8, hK8, mK8, ovasin, tumor-associated differentially expressed gene 14, TADG-14, NP, neuropsin)...
    3 KB (281 words) - 14:38, 26 August 2023
  • Kinin (category Kinin–kallikrein system)
    kininogens by the process of kallikreins. Kallikreins activate kinins when stimulated. It is a component of the kinin-kallikrein system. Their precursors...
    7 KB (820 words) - 12:07, 24 December 2023
  • kallikrein and a 60-amino acid polypeptide which was developed from a Kunitz domain through phage display to mimic antibodies inhibiting kallikrein....
    6 KB (517 words) - 20:11, 20 December 2023
  • Thumbnail for Stratum corneum
    to skin disorders. For example, a failure to modulate the activity of kallikreins via the disruption of the protease inhibitor LEKTI causes the debilitating...
    10 KB (1,119 words) - 15:09, 22 October 2024
  • contribute to the syndrome include serotonin, histamine, tachykinins, kallikrein, and prostaglandins with the greatest contribution appearing to be from...
    17 KB (1,814 words) - 18:30, 6 November 2024
  • Thumbnail for KLK14
    KLK14 (redirect from Kallikrein-14)
    Kallikrein-14 is a protein that in humans is encoded by the KLK14 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions...
    10 KB (1,185 words) - 18:53, 12 October 2024
  • Thumbnail for Alpha-2-Macroglobulin
    It functions as an inhibitor of fibrinolysis by inhibiting plasmin and kallikrein. It functions as an inhibitor of coagulation by inhibiting thrombin. α2-macroglobulin...
    14 KB (1,631 words) - 23:13, 9 November 2024
  • reduced), gamma-SM, antigen PSA (human prostate-specific), human glandular kallikrein, antigen PSA (human clone 5P1 protein moiety reduced)) is an enzyme. This...
    2 KB (172 words) - 15:48, 26 August 2023
  • Prekallikrein (category Kinin–kallikrein system)
    is the precursor of plasma kallikrein, which is a serine protease that activates kinins. PK is cleaved to produce kallikrein by activated Factor XII (Hageman...
    3 KB (366 words) - 21:28, 1 July 2021
  • Thumbnail for Coagulation
    prekallikrein, and FXII (Hageman factor). Prekallikrein is converted to kallikrein and FXII becomes FXIIa. FXIIa converts FXI into FXIa. Factor XIa activates...
    64 KB (6,553 words) - 17:35, 26 October 2024