Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells...

Keratinocyte carcinomas are a group of nonmelanoma skin cancers arising from the keratinocyte found in the epidermis of the human skin, namely: Basal-cell...

The keratinocyte growth factor (KGF), also known as FGF7, is a growth factor present in the epithelialization-phase of wound healing. In this phase, keratinocytes...

transglutaminase enzyme that in humans is encoded by the TGM1 gene. Keratinocyte transglutaminase enzymes serve to specifically catalyze the development...

to divide and produce new cells, and these are sometimes called basal keratinocyte stem cells. Others serve to anchor the epidermis glabrous skin (hairless)...

migration. Thus keratinocytes detach from the basement membrane and are able to enter the wound bed. Before they begin migrating, keratinocytes change shape...

HaCaT is a spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin, widely used in scientific research. HaCaT cells are...

be used in combination with benzoyl peroxide. Due to its effects on keratinocyte proliferation and differentiation, adapalene is superior to tretinoin...

epidermis is termed epidermal. The epidermis primarily consists of keratinocytes (proliferating basal and differentiated suprabasal), which comprise...

growth of keratin on the skin or on mucous membranes stemming from keratinocytes, the prominent cell type in the epidermis. More specifically, it can...

Hemidesmosomes are very small stud-like structures found in keratinocytes of the epidermis of skin that attach to the extracellular matrix. They are similar...

whales are also made of keratin. Keratin filaments are abundant in keratinocytes in the hornified layer of the epidermis; these are proteins which have...

scales off a fish'. Keratinocytes are the predominant cells of the epidermis, the outermost layer of the skin. Living keratinocytes reside in the basal...

it is composed of three to five layers of dead, flattened keratinocytes. The keratinocytes of the stratum lucidum do not feature distinct boundaries and...

special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes...

epithelium; four types of cells: keratinocytes, melanocytes, Merkel cells, and Langerhans cells. The predominant cell keratinocyte, which produces keratin, a...

Antiandrogen: A Study of 5α-reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line". Acta Dermatovenerologica Croatica. 25 (4): 271–275. PMID 30064598...

connections, such as desmosomes, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris. It is absent in bullous...

granulosum and stratum basale. This layer is composed of polyhedral keratinocytes. These are joined with desmosomes. Their spiny (Latin, spinosum) appearance...

Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. The protein encoded by this gene is a member of the fibroblast growth...

involves formation of anti-hemidesmosome antibodies, causing a loss of keratinocytes to basement membrane adhesion. Clinically, the earliest lesions may...

composed of proliferating basal and differentiated suprabasal keratinocytes. Keratinocytes are the major cells, constituting 95% of the epidermis, while...

across cell membranes. ABCA12 is thought to be a lipid transporter in keratinocytes necessary for lipid transport into lamellar granules during the formation...

Corneocytes are terminally differentiated keratinocytes and compose most of the stratum corneum, the outermost layer of the epidermis. They are regularly...

induce strong Ca2+ signals in cultured human keratinocytes. The long-term stimulation of keratinocytes with Sandalore positively affected cell proliferation...

icosahedral surface lattice. Papillomaviruses replicate exclusively in keratinocytes. Keratinocytes form the outermost layers of the skin, as well as some mucosal...

insulin-like growth factor receptors, which leads to proliferation of keratinocytes, fibroblasts and other cells in the skin. Activation of other growth...

dermis, and the outer, thinner epidermis. Vitamin D is produced in the keratinocytes of two innermost strata of the epidermis, the stratum basale and stratum...

that reach keratinocytes. Melanosomes, along with the melanin they contain, are transferred from melanocytes to keratinocytes when keratinocytes are low...

below the stratum corneum (stratum lucidum on the soles and palms). Keratinocytes migrating from the underlying stratum spinosum become known as granular...