• In population genetics, linkage disequilibrium (LD) is a measure of non-random association between segments of DNA (alleles) at different positions on...
    24 KB (3,515 words) - 19:46, 25 August 2024
  • In statistical genetics, linkage disequilibrium score regression (LDSR or LDSC) is a technique that aims to quantify the separate contributions of polygenic...
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  • equilibrioception Dialysis disequilibrium syndrome Political science Status-income disequilibrium Population genetics Linkage disequilibrium, the non-random association...
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  • Genome-wide association study Identity by descent Lander–Green algorithm Linkage disequilibrium Structural motif Cooper, DN; Krawczak, M; Polychronakos, C; Tyler-Smith...
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  • as "linkage disequilibrium mapping", is a method of mapping quantitative trait loci (QTLs) that takes advantage of historic linkage disequilibrium to link...
    11 KB (1,471 words) - 04:49, 13 October 2024
  • dominance, epistasis, the degree to which genetic recombination breaks linkage disequilibrium, and the random phenomena of mutation and genetic drift. This makes...
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  • nucleotide polymorphism (SNP) in a region of the genome with high linkage disequilibrium that represents a group of SNPs called a haplotype. It is possible...
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    genomics may also be used to detect inversions, using areas of high linkage disequilibrium as indicators for possible inversion sites. Human families that...
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    clear blocks of linkage disequilibrium, although with low recombination it can still lead to slightly negative linkage disequilibrium overall. Darwin's...
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  • the latter, because some linkage disequilibrium is initially needed to select for tighter linkage, and linkage disequilibrium requires both the previous...
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    as "linkage disequilibrium mapping", is a method of mapping quantitative trait loci (QTLs) that takes advantage of historic linkage disequilibrium to link...
    6 KB (568 words) - 13:03, 31 October 2024
  • linkage disequilibrium plays a large analytical role. The term linkage disequilibrium concedes that there may also be a disruption or lack of linkage...
    10 KB (1,258 words) - 16:50, 16 August 2024
  • locus and linkage disequilibrium in surrounding regions. White maize lines had increased diversity and no evidence of linkage disequilibrium associated...
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  • through a selective sweep, any other nearby polymorphisms that are in linkage disequilibrium will tend to change their allele frequencies too. Selective sweeps...
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    Data Analysis Heat Map Example: Displays the normalized linkage disequilibrium of Genomic Windows within the Hist1 region of a mouse (Mus musculus)....
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  • Vanja; Albrecht, Mark; Maiers, Martin (2015-09-07). "Asymmetric linkage disequilibrium: Tools for assessing multiallelic LD". Human Immunology. 77 (3):...
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  • disequilibrium test (TDT) was proposed by Spielman, McGinnis and Ewens (1993) as a family-based association test for the presence of genetic linkage between...
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    markers. However, there are information lost in the process such as linkage disequilibrium and zygosity information. Association studies can determine whether...
    58 KB (6,240 words) - 04:24, 29 September 2024
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    Longeri, Maria; Lyons, Leslie A. (January 7, 2013). "Extent of Linkage Disequilibrium in the Domestic Cat, Felis silvestris catus, and Its Breeds". PLOS...
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    chromosome" with this reference point. The authors interpreted this linkage disequilibrium in the Ashkenazi Jewish population as matching signs "of interbreeding...
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  • tests of Hardy–Weinberg equilibrium, inbreeding coefficient, etc.); Linkage disequilibrium (LD) calculation; Identity by descent (IBD) and identity by state...
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    a systems level. Another measure of correlation is linkage disequilibrium. Linkage disequilibrium describes the non-random association of genetic sequences...
    48 KB (5,550 words) - 09:16, 9 September 2024
  • application of the test in genetics is the transmission disequilibrium test for detecting linkage disequilibrium. The commonly used parameters to assess a diagnostic...
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  • unknown function or structure. RCCX modules exhibit a high degree of linkage disequilibrium, meaning that genes are inherited together more frequently than...
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    trait as well as genomic features like linkage disequilibrium. (One Bayesian method uses "linkage disequilibrium prediction" or LDpred.) More approaches...
    59 KB (6,725 words) - 04:30, 29 July 2024
  • A1-B8-DR3-DQ2 (AH8.1 in the most recent literature) Because of its strong linkage disequilibrium, each of the genes in the haplotype are markers for probable presence...
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  • proximity on the same chromosome; this is known as genetic linkage.[citation needed] Linkage disequilibrium (LD) is a term used in the study of population genetics...
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  • physical trait may also be selected for due to mechanisms like linkage disequilibrium. Often, juvenile behaviors are selected for in order to more easily...
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  • Thumbnail for Interbreeding between archaic and modern humans
    basis of linkage disequilibrium patterns, a recent admixture event is likewise confirmed by the data. From the extent of linkage disequilibrium, it was...
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    Genetic Variation at the ADH Genes Reveals Unusual Patterns of Linkage Disequilibrium and Diversity". American Journal of Human Genetics. 71 (1): 84–99...
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