• Thumbnail for MMP2
    (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene. The MMP2 gene is located on chromosome 16 at position 12.2. Proteins of the...
    24 KB (2,812 words) - 19:21, 13 December 2024
  • Thumbnail for Intracranial aneurysm
    interleukin 1 beta, interleukin 6, tumor necrosis factor alpha (TNF alpha), MMP1, MMP2, MMP9, prostaglandin E2, complement system, reactive oxygen species (ROS)...
    36 KB (3,912 words) - 03:51, 4 January 2025
  • Thumbnail for Cort Guitars
    with 'tree of life' inlay up the neck and finished in antique sunburst, an MMP2 and MMP3 available in "transparent cannon blue" and "brown burst" finishes...
    12 KB (1,191 words) - 14:46, 23 July 2024
  • CLGN secreted Substrates include Col I, II, III, VII, VIII, X, gelatin MMP2 Gelatinase-A, 72 kDa gelatinase secreted Substrates include Gelatin, Col...
    23 KB (2,312 words) - 20:35, 22 July 2024
  • Thumbnail for Winchester syndrome
    mutations in the matrix metalloproteinase 2 (MMP2) gene. A 2006 study showed other mutations found in the MMP2 gene. This has led to the belief that there...
    12 KB (1,287 words) - 14:14, 11 November 2024
  • Thumbnail for Bicuspid aortic valve
    reduced Fibrillin-1. It is currently believed that an increase in the ratio of MMP2 (Matrix Metalloproteinases 2) to TIMP1 (tissue inhibitors of metalloproteinase)...
    21 KB (2,392 words) - 17:33, 3 October 2024
  • Thumbnail for Astrocyte
    (PGE2). Activated astrocytes are also a source of matrix metalloproteinase 2 (MMP2), which induces pro-IL-1β cleavage and sustains astrocyte activation. In...
    82 KB (9,356 words) - 14:40, 25 November 2024
  • Thumbnail for Degenerative disc disease
    interleukin-1, and interleukin-6 polymorphisms. Mutation in genes – such as MMP2 and THBS2 – that encode for proteins and enzymes involved in the regulation...
    26 KB (3,145 words) - 19:20, 20 December 2024
  • Thumbnail for MicroRNA
    with increase in p53 effector genes including Bax, Trp53inp1, Jun, Cdkn1a, Mmp2, and Arid3a. p53 protein levels remained unchanged, suggesting that FoxD1...
    148 KB (16,818 words) - 22:42, 12 November 2024
  • Thumbnail for Michael Mällinen
    PVM Racing SEB1 SEB2 MMP1 4 MMP2 4 LIM1 LIM2 MOS1 MOS2 ATL1 ATL2 LS1 LS2 9th 20 2008 Leslie Racing SEB1 12 SEB2 14 MMP1 MMP2 LIM1 LIM2 MOS1 12 MOS2 11 ATL1...
    10 KB (435 words) - 00:32, 28 November 2024
  • Thumbnail for Disc herniation
    interleukin-1, and interleukin-6 polymorphisms. Mutation in genes – such as MMP2 and THBS2 – that encode for proteins and enzymes involved in the regulation...
    55 KB (6,629 words) - 18:51, 1 January 2025
  • Thumbnail for Hsp90
    the invasion step of metastasis by assisting the matrix metalloproteinase MMP2. Together with its co-chaperones, Hsp90 modulates tumour cell apoptosis "mediated...
    51 KB (5,551 words) - 15:05, 1 October 2024
  • Thumbnail for Alamandine
    decreased pro-inflammatory (IL-1β, TNF alpha and CCL2) and pro-fibrotic factors (MMP2 and TGF β1), and increased pro-resolution markers (MRC1 and FIZZ1) Almandine...
    10 KB (826 words) - 13:23, 20 November 2023
  • Thumbnail for MMP16
    protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. GRCh38:...
    8 KB (982 words) - 15:23, 5 April 2024
  • Thumbnail for Fibrillin-1
    vulnerable to be activated in a protease-dependent or independent manner. MMP2 and MMP9 are select TGF-β activators and ligands and are found in higher...
    29 KB (3,496 words) - 05:07, 30 September 2024
  • Thumbnail for Lymphangioleiomyomatosis
    Kwiatkowski DJ (February 2010). "Rapamycin-insensitive up-regulation of MMP2 and other genes in tuberous sclerosis complex 2-deficient lymphangioleiomyomatosis-like...
    100 KB (11,094 words) - 10:45, 2 November 2024
  • Thumbnail for Notch signaling pathway
    Notch may regulate this process by activating matrix metalloproteinase2 (MMP2) expression, or by inhibiting vascular endothelial (VE)-cadherin expression...
    95 KB (11,025 words) - 08:58, 16 December 2024
  • MMP1 MMP2 MMP3 LAG CTMP1 10 CTMP2 4 CTMP3 7 MidO1 MidO2 SNM1 SNM2 SNM3 - - - - 2012 98 Steve Blethen MYM/iTraycer Mazda RX-8 TC STP1 STP2 MMP1 MMP2 MMP3...
    33 KB (1,243 words) - 22:56, 12 December 2024
  • HGNC:14668 Q495T6 9654 MMGT1 HGNC:28100 Q8N4V1 9655 MMP1 HGNC:7155 P03956 9656 MMP2 HGNC:7166 P08253 9657 MMP3 HGNC:7173 P08254 9658 MMP7 HGNC:7174 P09237 9659...
    277 KB (17 words) - 18:41, 6 October 2024
  • Chang K, Oi Y, Milewicz DM (*Authors contribution equal). Association of MMP2 and MMP9 polymorphisms with intracranial aneurysms. J Neurosurg. 105(3):418-23...
    7 KB (851 words) - 04:46, 5 August 2023
  • Thumbnail for MMP25
    also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25...
    7 KB (818 words) - 05:03, 25 December 2024
  • Thumbnail for Basigin
    (August 2002). "Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway"...
    22 KB (2,517 words) - 03:08, 29 September 2024
  • gelatinases expressed are matrix metalloproteinases MMP2 and MMP9. Additionally, gelatinases A (MMP2) and B (MMP9) have been proven to assist in developing...
    10 KB (1,248 words) - 20:16, 30 November 2024
  • Thumbnail for PAK5
    SN, Qian HY, Wu JX, Tian H, Pei DS, Zheng JN (October 2013). "PAK5-Egr1-MMP2 signaling controls the migration and invasion in breast cancer cell". Tumour...
    18 KB (2,175 words) - 23:02, 28 December 2023
  • Thumbnail for Bicyclo(6.2.0)decapentaene
    bond has a π bond order of 0.1. It may appear to follow Hückel's rule, but MMP2 calculations predict that it is anti-aromatic, with a resonance energy of...
    6 KB (698 words) - 00:55, 13 December 2024
  • Thumbnail for MMP17
    MMPs, opposite to the more common transmembrane MMPs. The protein activates MMP2 by cleavage. In melanocytic cells MMP17 gene expression may be regulated...
    8 KB (946 words) - 01:05, 4 March 2023
  • Thumbnail for Peptidoglycan binding domain
    metastasis. Humans genes encoding proteins containing this domain include: MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17...
    6 KB (674 words) - 15:13, 1 October 2024
  • Thumbnail for Invadopodia
    are considered mature when matrix metalloproteases (MMPs), specifically MMP2, 9, and 14, are recruited to the invadopodium to be released into the extracellular...
    13 KB (1,535 words) - 03:47, 12 June 2024
  • Thumbnail for MMP24
    expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been...
    5 KB (620 words) - 01:09, 5 October 2022
  • founding member of this protein family) matrix metalloproteinases: MMP1, MMP2, MMP3, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17...
    4 KB (414 words) - 21:06, 6 July 2021