Naloxone is an opioid antagonist: a medication used to reverse or reduce the effects of opioids. For example, it is used to restore breathing after an...
82 KB (7,428 words) - 08:54, 17 November 2024
Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. It is...
34 KB (3,519 words) - 20:01, 2 November 2024
Oxycodone/naloxone, sold under the brand name Targin among others, is a combination pain medication. It is available as modified-release tablets and is...
7 KB (579 words) - 03:52, 8 July 2024
(+)-Naloxone (dextro-naloxone) is a drug which is the opposite enantiomer of the opioid antagonist drug (−)-naloxone. Unlike (−)-naloxone, (+)-naloxone has...
10 KB (1,017 words) - 21:48, 21 January 2024
buprenorphine/naloxone (Suboxone) is usually prescribed to discourage misuse by injection. However, more recently the efficacy of naloxone in preventing...
83 KB (7,718 words) - 07:53, 20 November 2024
Opioid overdose (section Naloxone)
the risk of hypoxia. Naloxone is then recommended to those who cannot reverse the opioid's effects through breathing. Giving naloxone via nasal administration...
52 KB (5,487 words) - 07:02, 14 September 2024
Tianeptine/naloxone (developmental code names TNX-601, TNX-601-CR, TNX-601-ER), or naloxone/tianeptine, is an extended-release combination of tianeptine...
7 KB (487 words) - 20:32, 1 November 2024
take-home naloxone program is a governmental program that provides naloxone drug kits to those that are at risk of an opioid overdose. Naloxone is a medication...
16 KB (2,063 words) - 05:31, 7 November 2024
of naloxone and training on its utilization are estimated to have prevented 10,000 opioid overdose deaths. Healthcare institution-based naloxone prescription...
30 KB (2,841 words) - 17:26, 17 November 2024
available in a fixed combination with naloxone for oral administration (Valoron N and generics); the mixture of naloxone is claimed to lower the abuse liability...
13 KB (1,245 words) - 05:30, 7 October 2024
medical use in 1964. Usually, in its oral formulations, it is combined with naloxone so as to prevent people from crushing the tablets, dissolving them in a...
14 KB (1,264 words) - 18:10, 21 October 2024
products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin. Common side effects include euphoria, constipation...
125 KB (11,618 words) - 04:34, 19 November 2024
also be useful to prevent relapse. Naloxone is useful for treating an opioid overdose and giving those at risk naloxone to take home is beneficial. This...
134 KB (14,334 words) - 20:49, 19 November 2024
Coma cocktail (section Naloxone)
IV), flumazenil (0.2 mg IV), naloxone (2 mg IV), and thiamine (100 mg IV). It has been suggested that the use of naloxone and flumazenil be administered...
7 KB (809 words) - 06:09, 12 September 2024
spray, though other forms of naloxone are administered intravenously. For example, the FDA has approved Evzio as a naloxone auto-injector, which includes...
23 KB (2,490 words) - 20:26, 4 November 2024
such as hydrocodone, oxycodone, and fentanyl; antagonist drugs such as naloxone; and endogenous peptides such as endorphins. The terms opiate and narcotic...
222 KB (19,663 words) - 09:17, 17 November 2024
general, Levine signed an order allowing law enforcement officers to carry naloxone. In July 2017, Governor Wolf appointed Levine as Secretary of Health, and...
37 KB (2,722 words) - 20:53, 21 November 2024
long-term remission rates were similar to those seen in clinical buprenorphine/naloxone administration. The consequence of relapse when weighing the best course...
108 KB (10,589 words) - 18:43, 13 November 2024
Harm reduction (section Naloxone distribution)
[dead link] Naloxone is a drug used to counter an overdose from the effect of opioids; for example, a heroin or morphine overdose. Naloxone displaces the...
91 KB (9,671 words) - 15:59, 21 November 2024
effects were observed in Nav1.7 null mice treated with naloxone. As such, opioid antagonists like naloxone and naltrexone may be effective in treating the condition...
14 KB (1,448 words) - 12:59, 15 October 2024
carfentanil, including overdose, can be reversed by the opioid antagonists naloxone and naltrexone, though higher doses than usual may be necessary compared...
22 KB (2,040 words) - 03:55, 17 November 2024
closely related to naloxone. It exists in two isomeric forms, α-naloxol and β-naloxol. α-naloxol is a human metabolite of naloxone. Synthetically, α-naloxol...
4 KB (141 words) - 20:16, 27 May 2022
are frequently used in the hospital setting and these are naloxone and flumazenil. Naloxone is an opioid antagonist and reverses the central nervous depressive...
6 KB (740 words) - 18:59, 21 June 2024
receptor antagonist that acts on one or more of the opioid receptors. Naloxone and naltrexone are commonly used opioid antagonist drugs which are competitive...
11 KB (1,340 words) - 14:34, 24 July 2024
hydrocodone, hydromorphone, oxycodone and oxymorphone, and the opioid antagonist naloxone. The physiological behavior of morphinans (naturally occurring and semi-synthetic...
7 KB (605 words) - 00:28, 26 March 2024
buprenorphine, methadone, or naltrexone. A heroin overdose may be treated with naloxone. As of 2015, an estimated 17 million people use opiates, of which heroin...
116 KB (11,944 words) - 17:09, 1 November 2024
case study suggests that the antidote to dextromethorphan overdose is naloxone, administered intravenously. In addition to producing PCP-like mental effects...
33 KB (3,508 words) - 07:06, 19 November 2024
cocaine and heroin) can synergistically exacerbate fentanyl's side effects. Naloxone (also known as Narcan) can reverse the effects of an opioid overdose, but...
174 KB (16,192 words) - 14:54, 18 November 2024
carfentanil. Reversing a gray death overdose may require multiple doses of naloxone. By contrast, an overdose from morphine or from high-purity heroin would...
4 KB (413 words) - 14:27, 18 October 2024
pentazocine/tripelennamine ("T's and blues") after the pharmaceutical industry added naloxone to its constitutent drugs, effectively blocking their potential for abuse...
34 KB (3,196 words) - 20:47, 19 November 2024