Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. For sleeping sickness it is used together...
18 KB (1,326 words) - 13:53, 2 August 2024
Early infections are treatable with the medications benznidazole or nifurtimox, which usually cure the disease if given shortly after the person is infected...
68 KB (7,303 words) - 18:56, 19 November 2024
Nifurtimox/eflornithine is a combination of two antiparasitic drugs, nifurtimox and eflornithine, used in the treatment of African trypanosomiasis (sleeping...
4 KB (284 words) - 18:01, 31 August 2023
stage of sleeping sickness caused by T. b. gambiense and may be used with nifurtimox. It is taken intravenously (injection into a vein) or topically. It is...
38 KB (3,966 words) - 22:31, 11 November 2024
Treatment of the second stage has involved eflornithine or a combination of nifurtimox and eflornithine for TbG. Fexinidazole is a more recent treatment that...
78 KB (7,299 words) - 03:26, 19 November 2024
toxicity levels are used during stage 1 of the disease. The approval of the nifurtimox-eflornithine combination therapy (NECT) in 2009 for the treatment of T...
18 KB (1,744 words) - 02:47, 5 March 2024
Pentamidine Suramin sodium Eflornithine Melarsoprol Nifurtimox Complementary: Melarsoprolα Benznidazole Nifurtimox Ivermectin Ansuvimab Atoltivimab/maftivimab/odesivimab...
67 KB (4,835 words) - 08:21, 11 November 2024
formerly used food preservative Nifuratel — an antiprotozoal and antifungal Nifurtimox — an antiprotozoal FANFT, a potent nitrofuran derivative tumor initiator...
3 KB (314 words) - 01:30, 18 August 2024
Fexinidazole P01CB01 Meglumine antimonate P01CB02 Sodium stibogluconate P01CC01 Nifurtimox P01CC02 Nitrofural P01CD01 Melarsoprol P01CD02 Acetarsol P01CX01 Pentamidine...
4 KB (321 words) - 07:50, 18 April 2023
nifurquinazol (INN) nifursemizone (INN) nifursol (INN) nifurthiazole (INN) nifurtimox (INN) nifurtoinol (INN) nifurvidine (INN) nifurzide (INN) niguldipine...
9 KB (417 words) - 07:03, 15 August 2024
ethidium isometamidium chloride lonidamine melaminylthioarsenate melarsoprol nifurtimox pentamidine posaconazole puromycin quinapyramine salicylhydroxamic acid...
6 KB (483 words) - 20:42, 19 September 2023
the first-line treatment given its moderate side effects compared to nifurtimox. It is taken by mouth. Side effects are fairly common. They include rash...
21 KB (1,858 words) - 03:46, 29 January 2024
of thin and thick blood smears stained with Giemsa. Benznidazole and nifurtimox (though benznidazole is the only drug available in most of Latin America)...
55 KB (1,669 words) - 07:51, 17 November 2024
disease and was about four times as effective as the standard of care, nifurtimox. A clinical trial in 2022 demonstrated the efficacy of higher-dose primaquine...
19 KB (1,846 words) - 20:04, 16 December 2023
heart failure and severe heart lesions. Acute cases are treated with nifurtimox and benznidazole, but no effective therapy for chronic cases is currently...
27 KB (3,075 words) - 18:01, 12 April 2024
infections so drugs such as pentamidine and suramin, benznidazole and nifurtimox are used to treat infections. These drugs are effective but infections...
212 KB (22,374 words) - 21:08, 20 November 2024
greater than 95%. Two follow-up studies, one comparing acoziborole to nifurtimox/eflornithine and a double-blind, randomized trial of the drug based on...
5 KB (369 words) - 05:44, 21 September 2024
replicate. Acute Chagas disease can be treated using benznidazole or nifurtimox. Chronic chagas disease is asymptomatic and causes heart and gastrointestinal...
32 KB (3,716 words) - 02:51, 17 September 2024
individuals die of brain damage (reactive encephalopathy). Another drug, nifurtimox, recommended for Chagas disease (American trypanosomiasis), is itself...
108 KB (12,573 words) - 16:09, 2 November 2024
Fexinidazole Pentamidine Suramin sodium Eflornithine Nifurtimox Melarsoprolα Benznidazole Nifurtimox Ivermectin Ibuprofen Paracetamol Propranolol Adalimumabα...
38 KB (2,574 words) - 03:03, 15 July 2024
of 2015, the FDA has proscribed arsenical drugs in poultry in the US. Nifurtimox, a compound with known antiprotozoal activity, was demonstrated to be...
13 KB (1,531 words) - 19:10, 8 November 2023
Management Team in May 2015. Nifurtimox-eflornithine combination treatment (NECT), a combination therapy of nifurtimox and eflornithine, is the first...
43 KB (4,627 words) - 11:45, 4 September 2024
91% effective at treating sleeping sickness. Though less effective than nifurtimox with eflornithine in severe disease, fexinidazole has the benefit that...
21 KB (1,737 words) - 13:31, 23 April 2024
Dimetridazole QP51AA10 Ipronidazole QP51AB02 Sodium stibogluconate QP51AC01 Nifurtimox QP51AC02 Nitrofural QP51AD01 Arsthinol QP51AD02 Difetarsone QP51AD03 Glycobiarsol...
4 KB (276 words) - 01:18, 11 October 2023
sleeping sickness. The company will specifically make their products nifurtimox and suramin, the drugs of choice for the disease respectively, doubly...
15 KB (1,643 words) - 03:42, 3 December 2023
only two drugs in use for the treatment of Chagas disease, specifically nifurtimox and benznidazole. Both of these drugs require long use, cause adverse...
9 KB (1,052 words) - 08:27, 10 June 2024
furylfuramide MeSH D02.640.600.410 – nifuratel MeSH D02.640.600.480 – nifurtimox MeSH D02.640.600.566 – nitrofurantoin MeSH D02.640.600.691 – nitrofurazone...
192 KB (16,705 words) - 16:43, 9 February 2024
furylfuramide MeSH D03.383.312.649.410 – nifuratel MeSH D03.383.312.649.480 – nifurtimox MeSH D03.383.312.649.566 – nitrofurantoin MeSH D03.383.312.649.691 – nitrofurazone...
109 KB (10,094 words) - 16:51, 9 February 2024