• Thumbnail for Nigrostriatal pathway
    The nigrostriatal pathway is a bilateral dopaminergic pathway in the brain that connects the substantia nigra pars compacta (SNc) in the midbrain with...
    25 KB (3,058 words) - 00:12, 27 April 2024
  • Thumbnail for Dopaminergic pathways
    pathway, the mesocortical pathway, the nigrostriatal pathway, and the tuberoinfundibular pathway. The mesolimbic pathway and the mesocortical pathway...
    47 KB (4,229 words) - 07:37, 3 June 2024
  • structural changes within the mesolimbic pathway. Mesocortical pathway Nigrostriatal pathway Tuberoinfundibular pathway Antipsychotic Tardive dyskinesia Tolerance...
    29 KB (3,487 words) - 18:05, 24 September 2023
  • elderly). Although Parkinson's disease is primarily a disease of the nigrostriatal pathway and not the extrapyramidal system, loss of dopaminergic neurons...
    13 KB (1,359 words) - 06:00, 24 March 2024
  • Thumbnail for Tuberoinfundibular pathway
    Other major dopamine pathways include: Mesocortical pathway Mesolimbic pathway Nigrostriatal pathway Antipsychotic Dopamine Malenka RC, Nestler EJ, Hyman...
    2 KB (206 words) - 21:50, 21 October 2022
  • Thumbnail for Neural pathway
    the trend was toward naming pathways by their origin and termination.[citation needed] For example, the nigrostriatal pathway runs from the substantia nigra...
    10 KB (1,043 words) - 01:20, 5 April 2024
  • Thumbnail for Selegiline
    putamen of the striatum, thereby enhancing the signaling of the nigrostriatal pathway. Selegiline and other MAO-B inhibitors may also improve non-motor...
    235 KB (25,417 words) - 18:42, 6 July 2024
  • Thumbnail for Mesocortical pathway
    Other major dopamine pathways include: mesolimbic pathway nigrostriatal pathway tuberoinfundibular pathway Dopamine Schizophrenia Malenka EJ, Nestler SE,...
    4 KB (451 words) - 20:52, 23 January 2020
  • Thumbnail for Medium spiny neuron
    Boireau A, Bloch B, Gross CE (August 2000). "Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced...
    34 KB (4,043 words) - 04:11, 3 September 2023
  • Thumbnail for Extrapyramidal system
    modulated by various parts of the central nervous system, including the nigrostriatal pathway, the basal ganglia, the cerebellum, the vestibular nuclei, and different...
    4 KB (456 words) - 16:50, 18 February 2024
  • Thumbnail for Adipsia
    dopamine in thirst regulation involved the nigrostriatal pathway. After completely degenerating the pathway, the animal becomes adipsic, aphagic, and loses...
    14 KB (1,604 words) - 11:53, 29 December 2023
  • Thumbnail for Neuromodulation
    been found to be involved in responding to cues related to the reward pathway, enhancing signal detection and sensory attention, regulating homeostasis...
    31 KB (2,819 words) - 15:10, 6 July 2024
  • Thumbnail for Medial forebrain bundle
    from brainstem regions, including the ventral tegmental area and nigrostriatal pathway. The MFB passes through the lateral hypothalamus and the basal forebrain...
    10 KB (1,156 words) - 01:44, 20 August 2023
  • Thumbnail for List of regions in the human brain
    Mesocortical pathway Mesolimbic pathway Nigrostriatal pathway Tuberoinfundibular pathway Serotonergic pathways Raphe Nuclei Norepinephrine Pathways Locus coeruleus...
    21 KB (1,695 words) - 23:13, 27 May 2024
  • Thumbnail for Vesicular monoamine transporter 2
    histamine—from cellular cytosol into synaptic vesicles. In nigrostriatal pathway and mesolimbic pathway dopamine-releasing neurons, SLC18A2 function is also...
    17 KB (2,015 words) - 05:34, 27 November 2023
  • Thumbnail for Midbrain tegmentum
    is the substantia nigra which is an important part of the nigrostriatal pathway. This pathway serves to coordinate motor movements and when left unbalanced...
    5 KB (552 words) - 08:23, 22 June 2023
  • Thumbnail for Substantia nigra
    striatum. The nigral dopaminergic input to the striatum via the nigrostriatal pathway is intimately linked with the striatum's function. The co-dependence...
    43 KB (5,078 words) - 18:54, 22 June 2024
  • Thumbnail for Oxidopamine
    p-quinone can be obtained. Oxidopamine is directly injected into the nigrostriatal pathway, targeting the dopamine transporters (DAT). This can be done through...
    13 KB (1,345 words) - 23:25, 27 March 2024
  • Thumbnail for Parkinsonism
    resulting in the loss of dopaminergic nerve terminals along the nigrostriatal pathway, similar to idiopathic PD, MSA, PSP, CBD, and DLB. Barrett KE, Barman...
    26 KB (2,303 words) - 14:59, 23 June 2024
  • hypothalamus (LH) is involved in the initiation of eating. The nigrostriatal pathway, which includes the substantia nigra, the lateral hypothalamus,...
    65 KB (8,707 words) - 23:57, 26 April 2024
  • Thumbnail for Hypokinesia
    each other and with dopamine directly. In the basal ganglia, the nigrostriatal pathway is where GABA and dopamine are housed in the same neurons and released...
    34 KB (3,472 words) - 16:36, 28 February 2024
  • of akinetic mutism suggest a possible presynaptic deficit in the nigrostriatal pathway, which transmits dopamine. Some patients with akinetic mutism have...
    13 KB (1,344 words) - 14:53, 29 June 2024
  • Thumbnail for Tardive dyskinesia
    primarily from neuroleptic-induced dopamine supersensitivity in the nigrostriatal pathway, with the D2 dopamine receptor being most affected. Neuroleptics...
    34 KB (3,615 words) - 21:23, 27 June 2024
  • Thumbnail for Animal models of Parkinson's disease
    neurons. This model requires injecting the 6-OHDA directly into the nigrostriatal pathway, targeting the dopamine transporter (DAT).This can be performed...
    29 KB (3,147 words) - 15:08, 26 November 2023
  • Thumbnail for Dopamine
    substantia nigra pars compacta to the dorsal striatum, termed the nigrostriatal pathway, plays a significant role in the control of motor function and in...
    137 KB (14,073 words) - 14:31, 3 July 2024
  • Thumbnail for Rett syndrome
    on striatal GABAergic medium spiny neurons. Dysregulation of the nigrostriatal pathway is causative from Parkinson disease (PD) in humans. Toxic and/or...
    58 KB (6,242 words) - 03:21, 6 July 2024
  • Thumbnail for Dopamine (medication)
    use in positron emission tomography to assess the function of the nigrostriatal pathway. Dopamine should generally not be given to people who have a pheochromocytoma...
    17 KB (1,358 words) - 06:53, 20 June 2024
  • Thumbnail for Dopamine antagonist
    blockers and benzodiazepines Parkinsonism due to effects on the nigrostriatal pathway - includes tremors, bradykinesia and muscle rigidity risk factors...
    25 KB (2,401 words) - 02:56, 4 June 2024
  • neurons of the pars compacta project many of their axons along the nigrostriatal pathway to the dorsal striatum, where they release the neurotransmitter...
    9 KB (1,048 words) - 18:38, 5 July 2024
  • Thumbnail for 2-Imidazoline
    inhibitors in rats with a unilateral 6-hydroxydopamine lesion of the nigrostriatal pathway". British Journal of Pharmacology. 143 (8): 952–959. doi:10.1038/sj...
    10 KB (902 words) - 20:21, 28 August 2022