Phosphofructokinase-2 (6-phosphofructo-2-kinase, PFK-2) or fructose bisphosphatase-2 (FBPase-2), is an enzyme indirectly responsible for regulating the...
38 KB (4,241 words) - 14:47, 6 May 2024
Phosphofructokinase (PFK) is a kinase enzyme that phosphorylates fructose 6-phosphate in glycolysis. The enzyme-catalysed transfer of a phosphoryl group...
10 KB (1,044 words) - 08:43, 10 June 2024
Phosphofructokinase-1 (PFK-1) is one of the most important regulatory enzymes (EC 2.7.1.11) of glycolysis. It is an allosteric enzyme made of 4 subunits...
22 KB (2,567 words) - 19:24, 8 August 2024
PFP (enzyme) (redirect from Pyrophosphate dependent phosphofructokinase)
include: 6-phosphofructokinase (pyrophosphate), inorganic pyrophosphate-dependent phosphofructokinase, inorganic pyrophosphate-phosphofructokinase, pyrophosphate-dependent...
4 KB (401 words) - 22:31, 4 July 2024
metabolite that allosterically affects the activity of the enzymes phosphofructokinase 1 (PFK-1) and fructose 1,6-bisphosphatase (FBPase-1) to regulate...
9 KB (992 words) - 21:33, 13 July 2024
Phosphofructokinase deficiency is a rare muscular metabolic disorder, with an autosomal recessive inheritance pattern. It may affect humans as well as...
17 KB (1,797 words) - 14:39, 27 October 2023
chain containing both the enzymes fructose 2,6-bisphosphatase and phosphofructokinase-2. This covalent phosphorylation initiated by glucagon activates the...
24 KB (2,821 words) - 06:18, 10 July 2024
bifunctional enzyme fructose bisphosphatase-2 (PFKB1), activating the phosphofructokinase-2 (PFK-2) active site. PFK-2 increases production of fructose 2,6-bisphosphate...
121 KB (13,799 words) - 03:46, 30 July 2024
alkaline phosphatase fructose-bisphosphatase glucose-6-phosphatase phosphofructokinase-2 phosphoprotein phosphatase calcineurin 6-phytase phosphodiesterase...
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In enzymology, 1-phosphofructokinase (EC 2.7.1.56) is an enzyme that catalyzes the chemical reaction ATP + D-fructose 1-phosphate → ADP + D-fructose 1...
3 KB (346 words) - 15:59, 4 November 2023
Akt/PKB signaling pathway (redirect from PI/PI3K/AKT/BCL-2 pathway)
transcription factors and phosphorylation of phosphofructokinase-2 (PFK2) which activates phosphofructokinase-1 (PFK1). Protein kinase B PI3K/AKT/mTOR pathway...
37 KB (4,145 words) - 08:04, 3 July 2024
Protein kinase A (redirect from EC 2.7.11.11)
cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase (EC 2.7.11.11). PKA has several functions in the cell, including regulation of glycogen...
27 KB (2,665 words) - 17:03, 6 April 2024
Glucokinase regulatory protein (category Genes on human chromosome 2)
Wu C, Lange AJ, Agius L (July 2005). "Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of...
15 KB (1,696 words) - 00:07, 20 December 2023
chain containing both the enzymes fructose-2,6-bisphosphatase and phosphofructokinase-2. This covalent phosphorylation initiated by glucagon activates the...
26 KB (1,943 words) - 14:26, 28 July 2024
Glycolysis (section Phosphofructokinase)
glycolytic function of 6-phosphofructokinase". The Journal of Biological Chemistry. 249 (24): 7737–7741. doi:10.1016/S0021-9258(19)42029-2. PMID 4372217. Selig...
82 KB (8,803 words) - 18:42, 6 August 2024
Citric acid (redirect from 2-hydroxy-1,2,3-propanetricarboxylic acid)
by citrate. High concentrations of cytosolic citrate can inhibit phosphofructokinase, the catalyst of a rate-limiting step of glycolysis. This effect...
36 KB (3,659 words) - 22:42, 10 August 2024
Glucokinase (redirect from EC 2.7.1.2)
interaction between glucokinase and the "bifunctional enzyme" (phosphofructokinase-2/fructose-2,6-bisphosphatase), which also plays a role in the regulation...
44 KB (5,655 words) - 06:02, 17 August 2024
In enzymology, an ADP-specific phosphofructokinase (EC 2.7.1.146) is an enzyme that catalyzes the chemical reaction ADP + D-fructose 6-phosphate ⇌ {\displaystyle...
2 KB (179 words) - 13:00, 26 August 2023
Phosphoglycerate mutase (redirect from EC 2.7.5.3)
in the superfamily that also contains the phosphatase portion of phosphofructokinase 2 and prostatic acid phosphatase. The catalyzed mutase reaction involves...
15 KB (1,574 words) - 18:27, 25 July 2023
phosphorylating key glycolytic enzymes, such as hexokinase and phosphofructokinase 2. This leads to inhibition of forkhead box subfamily O transcription...
22 KB (2,576 words) - 03:03, 28 November 2023
gyrase. Additionally, in Escherichia coli K-12 it has been noted that phosphofructokinase (PFK) exists as a dimer under aerobic conditions and as a tetramer...
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– phosphofructokinases MeSH D08.811.913.696.620.225.850.500 – phosphofructokinase-1 MeSH D08.811.913.696.620.225.850.500.249 – phosphofructokinase-1,...
158 KB (15,232 words) - 06:41, 8 March 2024
phosphofructokinase, or sedoheptulose 1,7-bisphosphate phosphatase show a significant decrease in the presence of 2-PG. Therefore, degradation of 2-PG...
8 KB (903 words) - 04:56, 23 March 2022
EC 2.7.1.53: L-xylulokinase EC 2.7.1.54: D-arabinokinase EC 2.7.1.55: allose kinase EC 2.7.1.56: 1-phosphofructokinase EC 2.7.1.57: deleted EC 2.7.1...
215 KB (21,664 words) - 23:41, 8 May 2024
falls to 5 or lower, the anaerobic fermentation of glucose through phosphofructokinase decreases sharply, which inhibits the growth and survival of microorganisms...
22 KB (1,823 words) - 12:13, 30 July 2024
using one water molecule and releasing one phosphate (in glycolysis, phosphofructokinase 1 converts F6P and ATP to F1,6BP and ADP). This is also the rate-limiting...
33 KB (3,705 words) - 18:48, 4 August 2024
fructose 6-phosphate into fructose 1,6-bisphosphate by the help of phosphofructokinase. Fructose 1,6-biphosphate then splits into two phosphorylated molecules...
30 KB (3,297 words) - 01:14, 21 June 2024
rhabdomyolysis: Glycolysis and glycogenolysis defects: McArdle's disease, phosphofructokinase deficiency, glycogen storage diseases VIII, IX, X and XI Lipid metabolism...
49 KB (4,816 words) - 10:13, 14 May 2024
converted to fructose 1,6-bisphosphate. This reaction is catalyzed by phosphofructokinase. While phosphorylation is performed by ATPs during preparatory steps...
15 KB (1,645 words) - 19:21, 22 June 2024
6-phosphofructokinase, muscle type is an enzyme that in humans is encoded by the PFKM gene on chromosome 12. Three phosphofructokinase isozymes exist in...
16 KB (1,928 words) - 22:13, 27 March 2024