• Thumbnail for Protein O-GlcNAcase
    Protein O-GlcNAcase (EC 3.2.1.169, OGA, glycoside hydrolase O-GlcNAcase, O-GlcNAcase, BtGH84, O-GlcNAc hydrolase) is an enzyme with systematic name...
    18 KB (2,159 words) - 20:53, 22 July 2024
  • Thumbnail for Protein O-GlcNAc transferase
    Protein O-GlcNAc transferase also known as OGT or O-linked N-acetylglucosaminyltransferase is an enzyme (EC 2.4.1.255) that in humans is encoded by the...
    25 KB (2,734 words) - 13:35, 21 January 2024
  • Thumbnail for O-GlcNAc
    regulate protein phosphorylation in humans, there are only 2 enzymes that regulate the cycling of O-GlcNAc: O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA)...
    108 KB (12,376 words) - 16:09, 30 March 2024
  • oga, an Ogg file containing audio Protein O-GlcNAcase, an enzyme that removes the post-translational modification O-GlcNAc Olga (disambiguation) This disambiguation...
    1 KB (190 words) - 16:51, 1 August 2024
  • enzymes. O-GlcNAc is added by O-GlcNAc transferase (OGT) and removed by O-GlcNAcase (OGA). Because there are only two enzymes that affect this specific modification...
    28 KB (3,150 words) - 21:50, 22 May 2024
  • Thumbnail for LY3372689
    Alzheimer's disease. It targets the enzyme O-GlcNAcase. Its result is to reduce formation of tau protein tangles. A molecule containing radioactive fluorine...
    4 KB (392 words) - 03:11, 6 October 2024
  • Thumbnail for Hexosaminidase
    Hexosaminidase (category Protein pages needing a picture)
    hexosaminidase A are shown below: The bifunctional protein NCOAT (nuclear cytoplasmic O-GlcNAcase and acetyltransferase) that is encoded by the MGEA5...
    16 KB (1,464 words) - 17:02, 27 September 2023
  • Thumbnail for Histone-modifying enzymes
    Histone-modifying enzymes (category Proteins)
    modifications. The addition and removal of GlcNAc groups are performed by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) respectively. While our understanding...
    33 KB (3,157 words) - 04:31, 13 August 2024
  • functions of active enzymes, of moonlighting proteins, the re-purposing of proteins in distinct cellular roles (Protein moonlighting). They are also suggesting...
    18 KB (1,389 words) - 15:14, 22 October 2024
  • Thumbnail for Endo-beta-n-acetylglucosaminidase
    van Aalten DM (February 2010). "Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds". FEBS Lett. 584 (4): 694–700. doi:10.1016/j.febslet...
    3 KB (452 words) - 23:18, 8 July 2024
  • Thumbnail for Gideon Davies
    Stubbs, Keith A; McEachern, Ernest J (2008). "A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo". Nature Chemical...
    21 KB (1,873 words) - 12:43, 19 October 2024
  • Thumbnail for Glycoside hydrolase
    potentially leading to lactose intolerance in adulthood. The enzyme O-GlcNAcase is involved in removal of N-acetylglucosamine groups from serine and...
    18 KB (1,932 words) - 08:37, 4 July 2024