• Thumbnail for SHC1
    SHC-transforming protein 1 is a protein that in humans is encoded by the SHC1 gene. SHC has been found to be important in the regulation of apoptosis and...
    13 KB (1,641 words) - 02:46, 29 November 2023
  • structural biology, a structural domain in signal transduction proteins SHC1, a human gene Sirohydrochlorin, a chemical precursor to various enzymes....
    2 KB (233 words) - 05:57, 16 September 2023
  • Thumbnail for Signal transducing adaptor protein
    protein complexes. Examples of adaptor proteins include MYD88, Grb2 and SHC1. Much of the specificity of signal transduction depends on the recruitment...
    6 KB (666 words) - 20:46, 24 January 2024
  • Thumbnail for SH2 domain
    SH2D1B; SH2D2A; SH2D3A; SH2D3C; SH2D4A; SH2D4B; SH2D5; SH2D6; SH3BP2; SHB; SHC1; SHC3; SHC4; SHD; SHE SLA; SLA2 SOCS1; SOCS2; SOCS3; SOCS4; SOCS5; SOCS6;...
    13 KB (1,341 words) - 04:09, 6 March 2024
  • Thumbnail for HER2
    DLG4, Erbin, GRB2, HSP90AA1, IL6ST, MUC1, PICK1 and PIK3R2, PLCG1, and SHC1. SkBr3 Cell Line, over-expresses HER2 GRCh38: Ensembl release 89: ENSG00000141736...
    43 KB (4,651 words) - 13:41, 27 July 2024
  • Thumbnail for GAB2
    GAB2 (section SHC1)
    adaptor protein, the Src homology domain-containing transforming protein 1 (SHC1), before being able to recruit SH2 domain-containing molecules. Ten SNPs...
    26 KB (3,191 words) - 05:41, 17 June 2024
  • Thumbnail for Chromosome 1
    SDHC (1q23) SELE (1q24) SFT2D2: encoding protein Sft2 domain containing 2 SHC1 (1q21) SHCBP1L: encoding protein Shc binding and spindle associated 1 like...
    46 KB (3,290 words) - 20:16, 17 August 2024
  • Thumbnail for Interleukin-4 receptor
    helminth infections. Interleukin-4 receptor has been shown to interact with SHC1. The N-terminal (extracellular) portion of interleukin-4 receptor is related...
    7 KB (781 words) - 08:35, 20 August 2024
  • Thumbnail for CD22
    transcription inhibition. CD22 has been shown to interact with Grb2, PTPN6, LYN, SHC1 and INPP5D. GRCm38: Ensembl release 89: ENSMUSG00000030577 – Ensembl, May...
    15 KB (1,738 words) - 05:58, 17 August 2024
  • Thumbnail for Janus kinase 2
    Grb2 GHR IRS1 IL12RB2 IL5RA PIK3R1 PPP2R4 PTK2 PTPN11 PTPN6 PRMT5 SH2B1 SHC1 SOCS3 STAT5A STAT5B STAM SOCS1 TEC TNFRSF1A VAV1 YES1 Prolactin signals through...
    28 KB (3,166 words) - 19:57, 8 August 2024
  • Thumbnail for Epidermal growth factor receptor
    PKC alpha, PLCG1, PLSCR1, PTPN1, PTPN11, PTPN6, PTPRK, SH2D3A, SH3KBP1, SHC1, SOS1, Src, STAT1, STAT3, STAT5A, UBC, and WAS, PAR2. In fruitflies, the...
    60 KB (6,879 words) - 14:26, 16 July 2024
  • Thumbnail for Kinase insert domain receptor
    insert domain receptor has been shown to interact with SHC2, Annexin A5 and SHC1. Cluster of differentiation VEGF receptors GRCh38: Ensembl release 89: ENSG00000128052...
    6 KB (794 words) - 11:50, 18 May 2022
  • Thumbnail for RET proto-oncogene
    interact with: DOK1, DOK5, GDNF family receptor alpha 1, GRB10, GRB7, Grb2, SHC1, and STAT3. GRCh38: Ensembl release 89: ENSG00000165731 – Ensembl, May 2017...
    21 KB (2,385 words) - 03:45, 16 December 2023
  • 2023. "Na Fianna knock out champions Kilmacud Crokes in thrilling Go-Ahead SHC1 quarter-final". Dublin GAA website. 1 October 2023. Retrieved 31 October...
    11 KB (300 words) - 19:29, 31 October 2023
  • Thumbnail for Amyloid-beta precursor protein
    APPBP1, APPBP2, BCAP31, BLMH CLSTN1, CAV1, COL25A1, FBLN1, GSN, HSD17B10, and SHC1. APP interacts with reelin, a protein implicated in a number of brain disorders...
    50 KB (5,683 words) - 05:16, 29 June 2024
  • Thumbnail for Tropomyosin receptor kinase A
    Abl gene, FRS2, Grb2, MATK, NGFB, PLCG1, RICS, SQSTM1, SH2B1, SH2B2, and SHC1. Small molecules such as amitriptyline and gambogic acid derivatives have...
    27 KB (3,264 words) - 05:43, 13 April 2024
  • HGNC:25321 Q9H0F6 14729 SHB HGNC:10838 Q15464 14730 SHBG HGNC:10839 P04278 14731 SHC1 HGNC:10840 P29353 14732 SHC2 HGNC:29869 P98077 14733 SHC3 HGNC:18181 Q92529...
    282 KB (17 words) - 07:55, 20 June 2024
  • Thumbnail for Estrogen receptor alpha
    NCOA2 NCOA3 NRIP1 PDLIM1 POU4F1 POU4F2 PRDM2 PRMT2 RBM39 RNF12 SAFB SAFB2 SHC1 SHP SMARCA4 SMARCE1 Src TR2 TR4 TDG TRIM24 and XBP1. GRCh38: Ensembl release...
    58 KB (6,133 words) - 05:31, 13 July 2024
  • Thumbnail for ABL (gene)
    NEDD9, NTRK1, P73, PAG1, PAK2, PSTPIP1, RAD9A, RAD51, RB1, RFX1, RYBP, SHC1, SORBS2, SPTA1, SPTAN1, TERF1, VAV1, and YTHDC1. There is some evidence that...
    30 KB (3,502 words) - 08:07, 14 August 2024
  • Thumbnail for Insulin-like growth factor 1 receptor
    GRB10, IRS1, Mdm2, NEDD4, PIK3R3, PTPN11, RAS p21 protein activator 1, SHC1 SOCS2, SOCS3, and YWHAE. There is evidence to suggest that IGF1R is negatively...
    29 KB (3,603 words) - 16:26, 25 May 2024
  • Thumbnail for Glycoprotein 130
    Grb2, HER2/neu, Janus kinase 1 Leukemia inhibitory factor receptor, PTPN11, SHC1, SOCS3, and TLE1. GRCh38: Ensembl release 89: ENSG00000134352 – Ensembl,...
    18 KB (2,202 words) - 01:16, 14 June 2024
  • Thumbnail for Granulocyte colony-stimulating factor receptor
    colony-stimulating factor receptor has been shown to interact with Grb2, HCK and SHC1. Cluster of differentiation GRCh38: Ensembl release 89: ENSG00000119535 –...
    13 KB (1,548 words) - 05:32, 17 August 2024
  • Thumbnail for GRB2
    PTPN12, PTPN1, PTPN6, PTPRA, RAPGEF1, RET proto-oncogene, SH2B1, SH3KBP1, SHC1, SOS1, Src, Syk, TNK2, TrkA, VAV1, VAV2, VAV3, and Wiskott-Aldrich syndrome...
    82 KB (9,365 words) - 15:39, 31 March 2024
  • Thumbnail for PLCG2
    shown to interact with: Bruton's tyrosine kinase, GAB2, LYN, PTPN11, and SHC1 GRCh38: Ensembl release 89: ENSG00000197943 – Ensembl, May 2017 GRCm38: Ensembl...
    12 KB (1,405 words) - 12:49, 23 December 2023
  • Thumbnail for Dystroglycan
    interact with FYN, C-src tyrosine kinase, Src, NCK1, Grb2, Caveolin 3 and SHC1. Dystrophin-associated protein complex Actin-binding protein Agrin GRCh38:...
    14 KB (1,615 words) - 14:41, 3 December 2023
  • Thumbnail for NCK1
    genes encoding human signal transduction adapter proteins, Nck (NCK), Shc (SHC1), and Grb2 (GRB2)". Genomics. 22 (2): 281–7. doi:10.1006/geno.1994.1385....
    28 KB (3,450 words) - 02:02, 6 May 2024
  • Thumbnail for ZAP70
    shown to interact with: Cbl gene, Drebrin-like, FYN, Lck, LAT, SHB, and SHC1. Lck Syk T cell receptor Chronic lymphocytic leukemia Combined immunodeficiency...
    23 KB (2,769 words) - 14:27, 11 December 2023
  • Thumbnail for LRP1
    Polymyxin B, Protein C inhibitor, Pseudomonas exotoxin A, RAP, Ricin A, SHC1, and Sphingolipid activator protein, SYNJ2BP. Tat, Thrombin, THBS1, Thrombospondin...
    32 KB (3,450 words) - 14:57, 7 September 2024
  • Thumbnail for PDGFRB
    Caveolin 1, Grb2, NCK1, NCK2, PDGFR-α, PTPN11, RAS p21 protein activator 1, SHC1 and Sodium-hydrogen antiporter 3 regulator 1. Cluster of differentiation...
    31 KB (3,403 words) - 18:14, 24 December 2023
  • Thumbnail for IL2RB
    cells. IL2RB has been shown to interact with: CISH, HGS, Janus kinase 1, and SHC1. IL-2 receptor IL-15 receptor GRCh38: Ensembl release 89: ENSG00000100385...
    14 KB (1,698 words) - 23:11, 14 October 2022