Synaptic pruning, a phase in the development of the nervous system, is the process of synapse elimination that occurs between early childhood and the onset...

process of synaptic pruning takes place in the brain of mammals during development (see also Neural Darwinism). A basic algorithm for pruning is as follows:...

individual's critical period, during which there is a certain degree of synaptic pruning due to competition for neural growth factors by neurons and synapses...

receptors, downregulation of this inhibitory receptor may increase global synaptic pruning activity. While difference in expression or distribution is observed[citation...

regulate behavior and engage in inhibitory control. As a result of synaptic pruning and myelination of the prefrontal cortex, improvements in executive...

pruning in Wiktionary, the free dictionary. Pruning is the practice of removing unwanted portions from a plant. Pruning may also refer to: Synaptic pruning...

neurons competing for connections). Microglia inherently play a role in synaptic pruning during adolescence. As resident immune cells of the central nervous...

generation of synapses between axons and their postsynaptic partners. The synaptic pruning that occurs in adolescence. The lifelong changes in synapses which...

anti-anxiety activity. GABAA receptors participate in the regulation of synaptic pruning by prompting microglial spine engulfment. Benzodiazepines have been...

identify the role of microglia and complement proteins in the "pruning" or removal of synaptic cells during brain development, and has also determined that...

cortex. These disruptions often occur during development linked with synaptic pruning dysfunction. People with bipolar disorder who are in a euthymic mood...

pruning of unused connections in thinking and processing. While this is occurring within the brain, retained connections are strengthened. Synaptic pruning...

combination of the occurrence of critical neuronal development and synaptic pruning of brain regions important for social behavior and environmental changes...

proteins of the classical complement pathway have an important role in synaptic pruning in the brain during early development. Janeway Jr CA, Travers P, Walport...

the brain follows an inverted-U pattern. Through a process called synaptic pruning, unnecessary neuronal connections in the brain are eliminated and the...

scaffold proteins, while pruning less active ones. For example, cell adhesion molecules (CAMs) play a large role in synaptic maintenance and stabilization...

the pruning hypothesis, which states that synesthesia is common in early childhood but diminishes throughout development through synaptic pruning. The...

phenomenon is a result of neuroplasticity, including Hebbian learning and synaptic pruning. Through these mechanisms, neural pathways that are more consistently...

most cells were unused, then this technique would have revealed that. Synaptic pruning: Brain cells that are not used have a tendency to degenerate. Hence...

plaques and neurofibrillary tangles, as well as neuronal cell death and synaptic pruning. The principle drug treatments on the market deal with antagonizing...

movement sleep and rapid eye movement sleep, and the impact sleep has on "synaptic pruning" and the creation of memories during a human's lifespan are also covered...

formed in excess, and experience and activity may lead to the pruning of extraneous synaptic connections. In lab animals of all ages, environmental enrichment...

Purkinje cells. In addition, several studies implicate progranulin in synaptic pruning, a microglial process that occurs during development of the neural...

School at Houston". nba.uth.tmc.edu. Sakai, Jill (14 July 2020). "How synaptic pruning shapes neural wiring during development and, possibly, in disease"...

has also been shown that microglia are involved in the process of synaptic pruning during brain development. Post-inflammation, microglia undergo several...

neuro-developmental process of maturation. It is possible that incomplete synaptic pruning during childhood development could lead to the continued maintenance...

20s. Accompanying the growth of the prefrontal cortex is continued synaptic pruning (the trimming of rarely used synapses) as well as increased myelination...

affect organizational processes of the brain such as neurogenesis, synaptic pruning, cell migration and cellular differentiation. This thus results in...

neurophysiological changes like slowed myelination, abnormalities in synaptic pruning, shrinking of the hippocampus, cognitive and affective impairment....

development of childhood peaks followed by adolescent declines (e.g. synaptic pruning). Consistent with adult findings, average cerebral volume is approximately...