The TIM barrel (triose-phosphate isomerase), also known as an alpha/beta barrel,: 252 is a conserved protein fold consisting of eight alpha helices (α-helices)...
46 KB (4,820 words) - 03:37, 17 May 2024
Barrel Man, real name Tim McKernan (September 5, 1940 – December 5, 2009), was a superfan of the Denver Broncos. In all types of weather for 30 years...
8 KB (727 words) - 18:09, 2 May 2024
Look up Tim, tim, or TIM in Wiktionary, the free dictionary. Tim or TIM may refer to: Timothy (given name) Tim (given name) Timmy Timo Timotheus Tim, Denmark...
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parallel to the barrel and the α-helix is in the outside of the barrel but does not contact the α-helices of the other repeats like in TIM barrels. The protein...
2 KB (256 words) - 21:14, 1 September 2023
and Barrel was voiced by Danny Elfman. In the Kingdom Hearts series, Lock was voiced by Jess Harnell, Shock was voiced by Kath Soucie, and Barrel was...
56 KB (8,064 words) - 19:06, 9 August 2024
In protein structures, a beta barrel (β barrel) is a beta sheet (β sheet) composed of tandem repeats that twists and coils to form a closed toroidal structure...
15 KB (1,669 words) - 20:34, 23 March 2024
or the immunoglobulin fold) or they can be closed β-barrels (such as the TIM barrel). β-Barrels are often described by their stagger or shear. Some open...
27 KB (3,120 words) - 01:54, 14 August 2024
— tryptophan synthase family Fold Type III — alanine racemase family (TIM-barrel) Fold Type IV — D-amino acid aminotransferase family Fold Type V — glycogen...
26 KB (2,937 words) - 22:00, 5 September 2024
Cracker Barrel Old Country Store, Inc., trading as Cracker Barrel, is an American chain of restaurant and gift stores with a Southern country theme. The...
69 KB (5,705 words) - 19:51, 9 September 2024
while another suggests that a stable TIM-barrel structure has evolved through convergent evolution. The TIM-barrel in pyruvate kinase is 'discontinuous'...
71 KB (8,443 words) - 19:00, 15 August 2024
eight alpha/beta barrels that create an active site holding two divalent magnesium ions. Xylose isomerase enzymes exhibit a TIM barrel fold with the active...
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families Clans of glycoside hydrolases Hierarchical classification of the TIM-barrel type glycoside hydrolases Bourne, Yves; Henrissat, Bernard (2001). "Glycoside...
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the proteins have from 209 to 241 amino acid residues. The enzyme has a TIM barrel structure. The systematic name of this enzyme class is D-ribulose-5-phosphate...
16 KB (1,876 words) - 18:16, 29 August 2024
proteins of diverse function and diverse evolution. For example, the TIM barrel, named for the enzyme triosephosphateisomerase, is a common tertiary structure...
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triosephosphate isomerase (TIM) barrel, pleckstrin homology (PH) domain, four tandem EF hand domains, and a C2 domain. The TIM barrel contains the active site...
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These enzymes are involved in purine metabolism. These enzymes adopt a TIM barrel structure. Whitby FG, Luecke H, Kuhn P, Somoza JR, Huete-Perez JA, Phillips...
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protein subunits of both classes each have an α/β domain folded into a TIM barrel containing the active site. Several subunits are assembled into the complete...
14 KB (1,622 words) - 14:06, 26 August 2023
αβ-barrel, or a TIM-barrel, and is by far the most commonly observed protein fold. The active site of this enzyme is in the center of the barrel. A glutamic...
11 KB (1,178 words) - 16:06, 26 August 2023
notable structural formations, including a type of β-barrel known as a jelly roll barrel and a TIM barrel. Human β-glucuronidase is homologous to the Escherichia...
24 KB (2,644 words) - 18:43, 11 December 2023
cysteine proteases by disrupting their structure. TIM barrel superfamily Members share a large α8β8 barrel structure. It is one of the most common protein...
24 KB (2,519 words) - 19:24, 3 September 2024
Lock, Stock and Two Smoking Barrels is a 1998 neo-noir black comedy crime film written and directed by Guy Ritchie. It follows a heist involving a confident...
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site of the enzyme. The catalytic domain of Beta-galactosidases have a TIM barrel core surrounded several other largely beta domains. The sugar binding...
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the N-terminal domain has an alpha-beta fold, the central domain has a TIM barrel fold, and the C-terminal domain has an all alpha helical fold....
6 KB (553 words) - 21:20, 6 August 2023
antiparallel helical bundle that plugs the C terminus of the N-terminal TIM barrel domain. The communication domain is thought to play an important role...
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consists of two TIM-barrel domains that bind homocysteine and N5-MeTHF individually. The two domains adopt a face-to-face double barrel architecture, which...
30 KB (3,437 words) - 07:25, 16 May 2024
The Nightmare Before Christmas (also known as Tim Burton's The Nightmare Before Christmas) is a 1993 American stop-motion animated musical fantasy film...
112 KB (10,335 words) - 01:48, 10 September 2024
Tim Simenon – production, mixing Q. – mixing, engineering Kerry Hopwood – programming Mike Marsh – mastering DiGravina, Tim. "Depeche Mode - Barrel of...
18 KB (1,397 words) - 16:49, 10 February 2024
central tunnel observed in most TIM barrel proteins, and pdxJ has three extra alpha helices compared to the classical TIM fold. These three extra helices...
11 KB (1,259 words) - 00:43, 3 December 2023
The flavodoxin fold is a common α/β protein fold, second only to the TIM barrel fold. It has three layers, with two α-helical layers sandwiching a 5-stranded...
1 KB (122 words) - 22:43, 23 November 2022
of 5-keto-4-deoxyuronate and 2,5-diketo-3-dexoygluconate. KduI has a TIM-barrel fold. This family also includes several bacterial Myo-inositol catabolism...
3 KB (285 words) - 13:50, 12 August 2023