• Thumbnail for Tropomyosin
    Tropomyosin is a two-stranded alpha-helical, coiled coil protein found in many animal and fungal cells. In animals, it is an important component of the...
    51 KB (6,192 words) - 22:52, 17 August 2024
  • Thumbnail for Tropomyosin 3
    Tropomyosin alpha-3 chain is a protein that in humans is encoded by the TPM3 gene. This gene encodes a member of the tropomyosin family of actin-binding...
    7 KB (888 words) - 20:23, 8 April 2022
  • In enzymology, a tropomyosin kinase (EC 2.7.11.28) is an enzyme that catalyzes the chemical reaction ATP + tropomyosin ⇌ {\displaystyle \rightleftharpoons...
    2 KB (191 words) - 16:09, 26 August 2023
  • Thumbnail for Troponin
    attached to the protein tropomyosin and lies within the groove between actin filaments in muscle tissue. In a relaxed muscle, tropomyosin blocks the attachment...
    30 KB (3,587 words) - 11:50, 25 November 2024
  • Thumbnail for Sarcomere
    The protein tropomyosin covers the myosin-binding sites of the actin molecules in the muscle cell. For a muscle cell to contract, tropomyosin must be moved...
    13 KB (1,609 words) - 18:28, 7 November 2024
  • Thumbnail for Tropomyosin receptor kinase A
    Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...
    28 KB (3,328 words) - 15:54, 29 October 2024
  • Thumbnail for Isotropic bands
    create the distinctive striped appearance of skeletal muscle tissue. Tropomyosin, a protein, shields the myosin-binding sites, hindering actin from binding...
    3 KB (325 words) - 22:08, 18 September 2024
  • Thumbnail for Dust mite allergy
    coughing or wheezing Tropomyosin, a minor allergen in dust mites, is also responsible for shellfish allergy. Exposure to inhaled tropomyosins from dust mites...
    22 KB (2,130 words) - 23:20, 6 November 2024
  • 'track') stands for tropomyosin receptor kinase or tyrosine receptor kinase (and not "tyrosine kinase receptor" nor "tropomyosin-related kinase", as has...
    27 KB (3,122 words) - 21:45, 8 July 2024
  • Thumbnail for Troponin I
    complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Troponin I prevents myosin from binding to actin in...
    18 KB (2,156 words) - 16:55, 16 November 2024
  • Thumbnail for ADF/Cofilin family
    monomers from the pointed end. "Older" ADP/ADP-Pi actin filaments free of tropomyosin and proper pH are required for cofilin to function effectively. In the...
    15 KB (1,907 words) - 02:03, 1 December 2023
  • Thumbnail for Tropomyosin receptor kinase B
    Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase,...
    39 KB (4,391 words) - 05:30, 23 October 2024
  • Thumbnail for Myofilament
    60 molecules of tropomyosin, the protein that blocks the active sites of the thin filaments when the muscle is relaxed. Each tropomyosin molecule has a...
    13 KB (1,711 words) - 18:04, 15 October 2023
  • Thumbnail for TPM2
    β-Tropomyosin, also known as tropomyosin beta chain is a protein that in humans is encoded by the TPM2 gene. β-tropomyosin is striated muscle-specific...
    24 KB (2,871 words) - 15:55, 2 November 2024
  • Thumbnail for TPM1
    Tropomyosin alpha-1 chain is a protein that in humans is encoded by the TPM1 gene. This gene is a member of the tropomyosin (Tm) family of highly conserved...
    13 KB (1,531 words) - 08:55, 4 November 2024
  • hepatitis. These antibodies can be directed against actin, troponin, and tropomyosin. Dawkins, RL; Joske RA (June 1973). "Immunoglobulin deposition in liver...
    1 KB (118 words) - 01:47, 12 August 2023
  • Thumbnail for Nerve growth factor
    NGF can drive the expression of genes such as bcl-2 by binding to the Tropomyosin receptor kinase A, which stimulates the proliferation and survival of...
    27 KB (3,064 words) - 04:17, 25 November 2024
  • Thumbnail for Sternocleidomastoid muscle
    results in the movement of troponin and tropomyosin on thin filaments. The movement of troponin and tropomyosin is key in facilitating the myosin head...
    12 KB (1,325 words) - 07:06, 18 November 2024
  • Thumbnail for House dust mite
    development and severity; they are estimated to contribute to 60-90% of cases. Tropomyosin, the major allergen in dust mites, is also responsible for shellfish...
    12 KB (1,078 words) - 17:29, 7 July 2024
  • it binds to the troponin of thin filaments, which causes the troponin-tropomyosin complex to change shape and allow the myosin heads to bind to the active...
    7 KB (811 words) - 06:43, 22 November 2024
  • Thumbnail for Muscle contraction
    binding site. The remainder of the actin binding site is blocked by tropomyosin. With the ATP hydrolyzed, the cocked myosin head now contains adenosine...
    62 KB (7,395 words) - 14:24, 5 October 2024
  • Thumbnail for Muscle
    other muscle proteins, present are two regulatory proteins, troponin and tropomyosin. Muscle tissue varies with function and location in the body. In vertebrates...
    23 KB (2,585 words) - 02:34, 15 November 2024
  • sequence and structure of other protein types (such as muscle protein tropomyosin). He retired in 2006. McLachlan was elected Fellow of the Royal Society...
    4 KB (319 words) - 00:00, 5 May 2024
  • Thumbnail for Triad (anatomy)
    to troponin and unmasking the binding sites covered by the troponin-tropomyosin complex on the actin myofilament and allowing the myosin cross-bridges...
    2 KB (263 words) - 22:03, 10 January 2024
  • Thumbnail for Actin
    such a large range of functions is regulated through the binding of tropomyosin along the filaments. A cell's ability to dynamically form microfilaments...
    153 KB (18,282 words) - 06:31, 29 October 2024
  • Thumbnail for Cardiac muscle
    myosin, and thin filaments composed of the proteins actin, troponin and tropomyosin. As the thick and thin filaments slide past each other the cell becomes...
    42 KB (5,130 words) - 05:03, 14 August 2024
  • Thumbnail for Shellfish allergy
    outcomes are mainly due to the protein tropomyosin causing an IgE mediated immune system response. Tropomyosin, the major allergen in shellfish allergy...
    40 KB (4,565 words) - 14:45, 2 November 2024
  • Thumbnail for Ponazuril
    ponazuril (also known as ACD855) is a positive allosteric modulator of the tropomyosin receptor kinases TrkA and TrkB. Clazuril Diclazuril Toltrazuril "Merial...
    4 KB (241 words) - 07:09, 23 October 2024
  • Thumbnail for TNNT2
    protein that in humans is encoded by the TNNT2 gene. Cardiac TnT is the tropomyosin-binding subunit of the troponin complex, which is located on the thin...
    48 KB (4,857 words) - 23:46, 3 January 2024
  • Thumbnail for Polypyrimidine tract
    isoforms distinguished by mutually exclusive exon selection in alpha-tropomyosin. Lodish H, Berk A, Matsudaira P, Kaiser CA, Krieger M, Scott MP, Zipursky...
    3 KB (321 words) - 17:00, 1 April 2020