U.S. Route 281 (US 281) is a north–south United States Numbered Highway. At 1,875 miles (3,018 km) it is the longest continuous three-digit U.S. Route...

U.S. Route 281 (US 281) is a United States Numbered Highway that runs from Brownsville near the Mexican border in the Rio Grande Valley to the Canadian...

U.S. Route 281 (US-281) is a part of the U.S. Highway System that runs from near the Mexican border north to the International Peace Garden, north of Dunseith...

U.S. Route 281 Alternate may refer to: U.S. Route 281 Alternate (Texas), an alternate route of U.S. Route 281 in South Texas U.S. Route 281 Alternate...

U.S. Route 277 (US 277, US-277) is a north–south United States Highway that is a spur route of U.S. Route 77. It no longer connects to its parent route...

west-northwest, meets U.S. Route 20 near Inman and the two routes overlap until US 275 ends at an intersection with U.S. Route 281 in downtown O'Neill....

U.S. Route 281 (US 281) is a part of the U.S. Highway System that travels from Hidalgo, Texas and Brownsville, Texas, to its northern terminus at the International...

Alternate U.S. Highway 281 (Alt. US 281) is a loop of the U.S. Highway System. The highway serves the small communities of Whitsett and Campbellton, about...

with U.S. Route 283 and U.S. Route 183. At Medicine Lodge, it intersects U.S. Route 281. It continues east and at Wellington, intersects U.S. Route 81 and...

U.S. Route 380 (US 380) is an east–west United States highway. The highway's eastern terminus is in Greenville, Texas at an intersection with Interstate...

U.S. Highway 159 (US 159) is a 83.6-mile-long (134.5 km) auxiliary route of US 59. It travels from Nortonville, Kansas at US 59 to New Point, Missouri...

U.S. Route 180 is an east–west United States highway. Like many three-digit routes, US 180 no longer meets its "parent", US 80. US 80 was decommissioned...

needed] it is the second longest three-digit U.S. Route, behind US 281. It serves as the major truck route between Dallas-Fort Worth and Amarillo, Texas...

miles (100 km) south of the city of Brandon on Manitoba Highway 10 / U.S. Route 281. It is a plateau 2,000 ft (600 m) above sea level, 300 ft to 400 ft...

resort/retirement town near the Mexico–U.S. border. Alamo is one of the Rio Grande Valley's gateways to Mexico, via U.S. Route 281 and Nuevo Progreso, Tamaulipas...

U.S. Route 20 or U.S. Highway 20 (US 20) is an east–west United States Numbered Highway that stretches from the Pacific Northwest east to New England....

U.S. Route 82 (US 82) is an east–west United States highway in the Southern United States. Created on July 1, 1931 across central Mississippi and southern...

U.S. Route 283 is a spur of U.S. Route 83. It currently runs for 731 miles (1,175 km) from Brady, Texas at U.S. Route 87 to Lexington, Nebraska at U.S...

U.S. Route 70 or U.S. Highway 70 (US 70) is an east–west United States highway that runs for 2,381 miles (3,832 km) from eastern North Carolina to east-central...

U.S. Route 34 (US 34) is an east–west United States highway that runs for 1,122 miles (1,806 km) from north-central Colorado to the western suburbs of...

at the 2020 census. Hamilton is located in central Hamilton County. U.S. Route 281 passes through the center of the city, leading north 21 miles (34 km)...

U.S. Route 212 (US 212) is a spur of US 12. It runs for 949 miles (1,527 km) from Yellowstone National Park to Minnesota Highway 62 at Edina, Minnesota...

U.S. Route 150 (US 150) is a 571-mile (919 km) long northwest–southeast United States highway, signed as east–west. It runs from U.S. Route 6 outside...

U.S. Route 136 is an east-west U.S. highway that is a spur route of U.S. Route 36. It runs from Edison, Nebraska, at U.S. Route 6 and U.S. Route 34 to...

United States Border Patrol interior checkpoint south of the city on U.S. Route 281. As an indirect consequence, many migrants seeking to bypass the checkpoint...

U.S. Route 2 or U.S. Highway 2 (US 2) is an east–west United States Numbered Highway spanning 2,571 miles (4,138 km) across the northern continental United...

and North Dakota with 24-hour service. The crossing is connected by U.S. Route 281 and North Dakota Highway 3 in Rolette County, North Dakota on the American...

Business US 281-W (Bus. US 281-W), which continues north on a reunited North Cage Boulevard through central Edinburg on US 281's former routing; meanwhile...

U.S. Route 183 (US 183) is a north–south United States highway. The highway's northern terminus is in Presho, South Dakota, at an intersection with Interstate...

U.S. Route 81 or U.S. Highway 81 (US 81) is a major north–south U.S. highway that extends for 1,220 miles (1,960 km) in the central United States and...