Apolipoprotein AI (Apo-AI) is a protein that in humans is encoded by the APOA1 gene. As the major component of HDL particles, it has a specific role in...
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multiple classes of apolipoproteins and several sub-classes: Apolipoprotein A (Apo-AI, Apo-A2, Apo-A4, and Apo-A5) Apolipoprotein B (Apo-B48 and Apo B-100)...
17 KB (1,891 words) - 23:30, 21 July 2024
Apolipoprotein C-III also known as apo-CIII, and apolipoprotein C3, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is secreted by...
20 KB (2,509 words) - 18:43, 2 October 2024
Apolipoprotein A-II is a protein that in humans is encoded by the APOA2 gene. It is the second most abundant protein of the high density lipoprotein particles...
10 KB (1,187 words) - 18:04, 24 January 2024
Apolipoprotein C-II (Apo-CII, or Apoc-II), or apolipoprotein C2 is a protein that in humans is encoded by the APOC2 gene. The protein encoded by this gene...
9 KB (1,102 words) - 08:56, 28 June 2024
doi:10.1038/sj.cdd.4401528. PMID 15592360. Kochneva-Pervukhova NV, Alexandrov AI, Ter-Avanesyan MD (2012). Tuite MF (ed.). "Amyloid-mediated sequestration...
60 KB (6,536 words) - 06:48, 29 August 2024
Apolipoprotein D (ApoD) is a protein that in humans is encoded by the APOD gene. Unlike other lipoproteins, which are mainly produced in the liver, apolipoprotein...
44 KB (4,897 words) - 14:15, 11 June 2024
mechanism, including Aβ amyloidosis, amyloid A (AA) amyloidosis, and apolipoprotein AII amyloidosis, tauopathy, synucleinopathy, and the aggregation of...
62 KB (4,598 words) - 21:08, 10 September 2024
APOA4 (category Apolipoproteins)
Apolipoprotein A-IV (also known as apoA-IV, apoAIV, or apoA4) is plasma protein that is the product of the human gene APOA4. APOA4 resides on chromosome...
10 KB (1,362 words) - 03:12, 21 June 2024
dense cholesterol transport particles, contain apolipoprotein B-48, apolipoprotein C, and apolipoprotein E (the principal cholesterol carrier in the brain)...
80 KB (8,638 words) - 23:17, 18 September 2024
"Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression...
13 KB (1,548 words) - 00:10, 6 October 2023
PMID 9818055. Soutar AK, Hawkins PN, Vigushin DM, et al. (August 1992). "Apolipoprotein AI mutation Arg-60 causes autosomal dominant amyloidosis". Proc. Natl...
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oriented inward toward the lipid center. A special kind of protein, called apolipoprotein, is embedded in the outer shell, both stabilising the complex and giving...
23 KB (2,599 words) - 18:32, 30 July 2024
the human lysozyme gene, as well as novel amyloidogenic variants of apolipoprotein AI and transthyretin. In 1999, he became director of the University College...
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acute regulatory protein increases macrophage cholesterol efflux to apolipoprotein AI". Cardiovascular Research. 86 (3): 526–34. doi:10.1093/cvr/cvq015...
11 KB (1,377 words) - 05:00, 15 December 2023
acute regulatory protein increases macrophage cholesterol efflux to apolipoprotein AI". Cardiovasc Res. 86 (3): 526–534. doi:10.1093/cvr/cvq015. PMID 20083572...
19 KB (2,294 words) - 06:13, 17 June 2024
observed in clinical trials. E. McNeill, RVX-208, a stimulator of apolipoprotein AI gene expression for the treatment of cardiovascular diseases, Current...
12 KB (1,265 words) - 20:20, 12 August 2023
Gelperina, S.; Langer, K. (2007). "Covalent attachment of apolipoprotein AI and apolipoprotein B-100 to albumin nanoparticles enables drug transport into...
19 KB (2,284 words) - 16:42, 9 October 2024
CER-001 is an artificially synthesized mimetic of recombinant human apolipoprotein AI (ApoA1), the main structural protein of natural HDL, together with...
10 KB (824 words) - 02:00, 29 September 2024
PMID 7568236. Ginsburg GS, Ozer J, Karathanasis SK (Jul 1995). "Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements...
18 KB (2,230 words) - 15:35, 22 August 2024
differentiate into dendritic cells by a self-peptide Ep1.B derived from apolipoprotein E. These are primarily tolerogenic plasmacytoid dendritic cells. In...
34 KB (3,972 words) - 15:36, 25 August 2024
Apolipoprotein A-I-binding protein also known as APOA1BP is a protein that in humans is encoded by the APOA1BP gene. Progressive encephalopathy with brain...
5 KB (605 words) - 02:07, 18 April 2024
lipoprotein cholesterol (LDL), total cholesterol, triglycerides (TG), and apolipoprotein B (apo B), and to increase high-density lipoprotein cholesterol (HDL)...
26 KB (2,514 words) - 21:09, 28 September 2024
enzyme Complement component 3, a protein of the innate immune system Apolipoprotein C3, a human very low density lipoprotein ATC code C03 Diuretics, a subgroup...
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development. The strongest genetic risk factor is from an allele of apolipoprotein E. Other risk factors include a history of head injury, clinical depression...
184 KB (19,556 words) - 02:51, 10 October 2024
β2-microglobulin, variants Musculoskeletal system ANS S S A H AApoAI Apolipoprotein A I, variants Heart, liver, kidney, PNS, testis, larynx (C terminal...
55 KB (5,426 words) - 12:05, 18 September 2024
lipase (LIPC), hepatocyte nuclear factor 4 alpha (HNF4A), Apolipoprotein AI (APOA1), Apolipoprotein L1 (APOL1) and Haptoglobin-related protein (HPR). Especially...
41 KB (4,538 words) - 20:56, 23 May 2024
P.; Wayne, R.K.; Springer, M.S. (2003). "A new phylogenetic marker, apolipoprotein B, provides compelling evidence for eutherian relationships". Molecular...
69 KB (6,705 words) - 15:30, 6 October 2024
List of diseases (A) (section Ai–Ak)
digits and nails Aplastic anemia Aplastic crisis Apo A-I deficiency Apolipoprotein C-II deficiency Apparent mineralocorticoid excess Appelt–Gerken–Lenz...
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as a likely explanation for observations that high cholesterol and apolipoprotein E genotype are major risk factors for Alzheimer's disease. Although...
50 KB (5,683 words) - 05:16, 29 June 2024