• practical interest. Aziridine was discovered in 1888 by the chemist Siegmund Gabriel. Its derivatives, also referred to as aziridines, are of broader interest...
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  • Thumbnail for Aziridines
    In organic chemistry, aziridines are organic compounds containing the aziridine functional group (chemical structure (R−)4C2N−R), a three-membered heterocycle...
    16 KB (1,680 words) - 13:29, 4 September 2024
  • synthesis is a name reaction of organic chemistry, for the generation of aziridines from oxiranes. The oxirane is first converted into a 2-azidoalcohol with...
    5 KB (483 words) - 11:12, 17 April 2024
  • Thumbnail for Johnson–Corey–Chaykovsky reaction
    chemical reaction used in organic chemistry for the synthesis of epoxides, aziridines, and cyclopropanes. It was discovered in 1961 by A. William Johnson and...
    22 KB (2,314 words) - 16:34, 26 September 2024
  • Thumbnail for Azomethine ylide
    pharmaceuticals. Azomethine ylides can be generated from many sources, including aziridines, imines, and iminiums. They are often generated in situ, and immediately...
    18 KB (1,988 words) - 01:46, 19 April 2024
  • The De Kimpe aziridine synthesis is a name reaction of organic chemistry, for the generation of aziridines by the reaction of α-chloroimines with nucleophiles...
    2 KB (247 words) - 14:35, 26 September 2024
  • unusual conversion of 1-alkyl-2-(bromomethyl)aziridines into 1-alkyl-2-(N-alkyl-N-ethylaminomethyl)aziridines using methyllithium Matthias D'hooghe and Norbert...
    6 KB (643 words) - 23:25, 10 March 2024
  • isoindole: Nitrene cycloaddition. With alkenes, nitrenes react to form aziridines, very often with nitrenoid precursors such as nosyl- or tosyl-substituted...
    11 KB (1,286 words) - 23:57, 31 May 2024
  • Chloride Promoted Highly Regioselective Ring Opening of Epoxides and Aziridines Using NaN 3 in Acetonitrile: A Facile Synthesis of 1,2-Azidoalcohols and...
    28 KB (2,880 words) - 17:35, 1 August 2024
  • "forward" (epoxide to aziridine) or "reverse" (aziridine to epoxide) direction depending on the conditions employed. Electron-poor aziridines undergo the reverse...
    14 KB (1,773 words) - 23:49, 28 April 2023
  • Thumbnail for Wenker synthesis
    doi:10.1021/ja01314a504. Steuerle, Ulrich; Feuerhake, Robert (2006). "Aziridines". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH...
    3 KB (253 words) - 20:59, 13 March 2024
  • (2013-08-20). "Directed Nickel-Catalyzed Negishi Cross Coupling of Alkyl Aziridines". Journal of the American Chemical Society. 135 (36): 13605–13609. doi:10...
    7 KB (445 words) - 00:36, 18 April 2024
  • Thumbnail for Aziridinium
    Aziridinium (category Aziridines)
    Aziridiniums are the ionic form of the class of molecules known as aziridines. Aziridines can be used to insert nitrogen atoms during synthesis, but without...
    3 KB (221 words) - 05:02, 25 September 2024
  • Thumbnail for Malignancy
    oxazaphosphorines, alkyl alkane, sulphonates, nitrosoureas, tetrazines and aziridines." Malignancy has been a constant global health concern for a number of...
    24 KB (2,529 words) - 22:39, 13 September 2024
  • Thumbnail for Amine
    R″ groups are constrained in cyclic structures such as N-substituted aziridines (quaternary ammonium salts are resolvable). In aromatic amines ("anilines")...
    36 KB (3,789 words) - 17:13, 18 September 2024
  • Thumbnail for 2-tert-Butyl-1,1,3,3-tetramethylguanidine
    many organic reactions, including in alkylations and in the formation of aziridines. It is often a milder alternative to traditional, strong inorganic bases...
    3 KB (185 words) - 07:01, 11 August 2022
  • Thumbnail for Sodium amide
    as in the preparation of methylenecyclopropane below. Cyclopropenes, aziridines and cyclobutanes may be formed in a similar manner. Carbon acids which...
    13 KB (1,641 words) - 18:17, 23 June 2024
  • ammonia. Intramolecular reactions of haloamines X-(CH2)n-NH2 give cyclic aziridines, azetidines and pyrrolidines. N-alkylation is a general and useful route...
    6 KB (814 words) - 00:53, 9 July 2022
  • Thumbnail for Tretinoin
    Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine Platinum-based Carboplatin#...
    31 KB (2,908 words) - 06:38, 22 September 2024
  • Thumbnail for Taurine
    aqueous sodium bisulfite. A direct approach involves the reaction of aziridine with sulfurous acid. In 1993, about 5000–6000 tonnes of taurine were produced...
    29 KB (3,083 words) - 14:34, 22 September 2024
  • Thumbnail for Imine
    of an epoxide. Thus, ethylenimine is the three-membered ring species aziridine C2H4NH. The relationship of imines to amines having double and single...
    23 KB (2,633 words) - 01:56, 2 September 2024
  • Thumbnail for Methotrexate
    Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine Platinum-based Carboplatin#...
    36 KB (3,299 words) - 19:46, 10 August 2024
  • Thumbnail for Hydroxycarbamide
    Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine Platinum-based Carboplatin#...
    20 KB (1,809 words) - 14:07, 16 September 2024
  • Propyleneimine (category Aziridines)
    the synthesis of dendrimers, a process that exploits the tendency of aziridines to undergo ring-opening reactions. NIOSH considers propyleneimine a potential...
    4 KB (323 words) - 19:56, 5 September 2024
  • Thumbnail for Diphosphorus tetraiodide
    alkenes and aldoximes into nitriles. It can also cyclize 2-aminoalcohols to aziridines and to convert α,β-unsaturated carboxylic acids to α,β-unsaturated bromides...
    6 KB (556 words) - 15:37, 1 June 2023
  • C2H5N (molar mass: 43.07 g/mol, exact mass: 43.0422 u) can refer to: Aziridine Ethanimine or its tautomer, vinylamine N-Methylmethanimine This set index...
    297 bytes (61 words) - 20:58, 27 December 2022
  • Thumbnail for Vincristine
    Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone Thiotepa Triaziquone Triethylenemelamine Platinum-based Carboplatin#...
    31 KB (2,832 words) - 13:30, 20 September 2024
  • aldehyde or by thermal ring opening reaction of certain N-substituted aziridines. The further-unsaturated nitrile ylides are known almost exclusively as...
    10 KB (1,152 words) - 18:33, 21 August 2024
  • Thumbnail for Ring strain
    cyclobutanes, cyclobutenes, [1,1,1]propellanes, [2,2,2]propellanes, epoxides, aziridines, cyclopentenes, and norbornenes. These molecules have bond angles between...
    16 KB (1,856 words) - 13:05, 22 September 2024
  • Thumbnail for Mitomycins
    Mitomycins (category Aziridines)
    The mitomycins are a family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae. They include mitomycin...
    9 KB (953 words) - 14:07, 17 January 2024