Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene (RPD ID - 5T5N/4RDQ). The bestrophin family of proteins comprises four...

Bestrophin-2 is a protein that in humans is encoded by the BEST2 gene. This gene is a member of the bestrophin gene family of anion channels. Bestrophin...

potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded...

the cardiac pacemaker ("funny") current". Pharmacology & Therapeutics. 107 (1): 59–79. doi:10.1016/j.pharmthera.2005.01.005. PMID 15963351. DiFrancesco...

transporters, or permeases). Examples of channel/carrier proteins include the GLUT 1 uniporter, sodium channels, and potassium channels. The solute carriers and...

CFTR chloride channel". Physiological Reviews. 79 (1 Suppl): S23–S45. doi:10.1152/physrev.1999.79.1.S23. PMID 9922375. Zhang Z, Liu F, Chen J (December...

Polycystin 1 (PC1) is a protein that in humans is encoded by the PKD1 gene. Mutations of PKD1 are associated with most cases of autosomal dominant polycystic...

(FUP) family 1.B.12 Autotransporter-1 (AT-1) family 1.B.13 Alginate export porin (AEP) family 1.B.14 Outer membrane receptor (OMR) family 1.B.15 Raffinose...

and Pharmacology of the Superfamilies (1 ed.). Boca Raton: CRC Press. doi:10.1201/9781003096276. ISBN 978-1-003-09627-6. S2CID 259784278. Wu, Jianping;...

binding of the Ca2+-binding signaling protein calmodulin (CaM) to at least 1 site on the channel, as Ca2+-null CaM mutants abolish CGI in L-type channels...

calcium-dependent chloride channels, monovalent cation:proton antiporters, type 1, and potassium transporters. Potassium channel Catecholaminergic polymorphic...

independent gating variables. Each of these variables can attain a value between 1 (fully permeant to ions) and 0 (fully non-permeant), the product of these...

(2012). "Acidosis differentially modulates inactivation in na(v)1.2, na(v)1.4, and na(v)1.5 channels". Frontiers in Pharmacology. 3: 109. doi:10.3389/fphar...

the channel is a heterotrimeric protein like the acid-sensing ion channel 1 (ASIC1), which belongs to the same family. Each of the subunits consists of...

channels consists of approximately 13 members. They include ClCs, CLICs, Bestrophins and CFTRs. These channels are non-selective for small anions; however...

extracellular N-terminal ligand-binding domain gives them receptor specificity for (1) acetylcholine (AcCh), (2) serotonin, (3) glycine, (4) glutamate and (5) γ-aminobutyric...

pressure measurement". The Journal of General Physiology. 44 (1): 1–17. doi:10.1085/jgp.44.1.1. PMC 2195086. PMID 13706631. Dainty, J.; House, C. R. (1966-07-01)...

"hemichannels": a critical appraisal". Glia. 54 (7): 758–73. CiteSeerX 10.1.1.124.4117. doi:10.1002/glia.20429. PMID 17006904. S2CID 17677517. Baroja-Mazo...

like other known channels. The chloride channel subunits contain between 1 and 12 transmembrane segments. Some chloride channels are activated only by...

identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been identified along...

12q13 on the basis of two-color FISH". Cytogenetics and Cell Genetics. 68 (1–2): 45–8. doi:10.1159/000133885. PMID 7525161. Nielsen S, Chou CL, Marples...

Aquaporin 1 (AQP-1) is a protein that in humans is encoded by the AQP1 gene. AQP-1 is a widely expressed water channel, whose physiological function has...

complex or nexus. These components include the tight junction protein ZO-1—a protein that holds membrane content together and adds structural clarity...

ryanodine receptors on the intracellular calcium stores with cell surface group 1 metabotropic glutamate receptors and the Alpha-1D adrenergic receptor The...

receptor 1-induced glutamate release in cultured astrocytes is mediated by Bestrophin-1 channel but not by vesicular exocytosis". Molecular Brain. 5 (1): 38...

Cav1.1 also known as the calcium channel, voltage-dependent, L type, alpha 1S subunit, (CACNA1S), is a protein which in humans is encoded by the CACNA1S...

sur1 and kir6.2 genes are located in chr11p15.1 while kir6.1 and sur2 genes reside in chr12p12.1. The kir6.1 and kir6.2 genes encode the pore-forming subunits...

1.A.46 Anion channel-forming bestrophin family 1.A.47 Nucleotide-sensitive anion-selective channel, ICln family 1.A.48 Anion channel Tweety family 1.A...

the cardiac pacemaker ("funny") current". Pharmacology & Therapeutics. 107 (1): 59–79. doi:10.1016/j.pharmthera.2005.01.005. PMID 15963351. Santoro, B;...

where it spans more than 100 kb. The gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5' untranslated region (5’UTR) and exon 28 the...