Homeotic protein bicoid is encoded by the bcd maternal effect gene in Drosophilia. Homeotic protein bicoid concentration gradient patterns the anterior-posterior...
11 KB (1,170 words) - 23:57, 18 May 2024
specific set of gap or pair-rule genes. In flies, stripe 2 in the embryo is activated by the maternal proteins Bicoid and Hunchback, but repressed by the...
51 KB (6,108 words) - 10:20, 12 August 2024
regulated by the bicoid gene in Drosophila. However, in the red flour beetle, there is no bicoid orthologue, but instead the genes orthodenticle and...
20 KB (2,385 words) - 00:23, 26 April 2024
genes involved in segmentation, the pair-rule genes. The gap genes themselves are expressed under the control of maternal effect genes such as bicoid...
7 KB (901 words) - 14:58, 18 October 2023
differentiation. Maternal-effect genes help to define the anterior-posterior axis using Bicoid (gene) and Nanos (gene). Gap genes establish 3 broad segments...
44 KB (6,363 words) - 20:09, 1 August 2024
The bicoid 3′-UTR regulatory element is an mRNA regulatory element that controls the gene expression of the bicoid protein in fruitfly Drosophila melanogaster...
3 KB (230 words) - 10:33, 29 January 2023
development, the genes nanos and bicoid are asymmetrically expressed in the oocyte because maternal cells deposit messenger RNA (mRNA) for these genes in the poles...
12 KB (1,411 words) - 18:08, 29 April 2024
number of genes produce messenger RNAs that set up concentration gradients along the long axis of the embryo. In the early embryo, the bicoid and hunchback...
57 KB (6,279 words) - 17:31, 21 May 2024
Morphogenesis (redirect from Nanos gene)
for by master regulatory genes, and either activate or deactivate the transcription of other genes; in turn, these secondary gene products can regulate the...
25 KB (2,724 words) - 18:06, 10 August 2024
Sex-determining region Y protein (redirect from SR-Y gene)
is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of...
39 KB (4,855 words) - 12:42, 9 August 2024
Morphogen (section Genes and signals)
Lawrence. Christiane Nüsslein-Volhard was the first to identify a morphogen, Bicoid, one of the transcription factors present in a gradient in the Drosophila...
16 KB (1,856 words) - 04:38, 25 July 2024
embryo. This allows the maternal effect genes Hunchback, Bicoid, Nanos, and Caudal to regulate zygotic genes to create different identities for different...
17 KB (1,683 words) - 01:19, 22 June 2024
Orthodenticle (category Drosophila melanogaster genes)
the blastoderm, bicoid in low concentrations is sufficient to activate otd expression through an enhancer located upstream of the otd gene. Later, in the...
11 KB (1,289 words) - 23:16, 19 February 2023
Drosophila embryogenesis (redirect from Nanos (gene))
establish concentration gradients that span the egg. Bicoid and Hunchback are the maternal effect genes that are most important for patterning of anterior...
21 KB (2,688 words) - 03:15, 29 June 2024
Homeobox (redirect from Homeobox gene)
target genes. Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can...
41 KB (4,385 words) - 07:06, 25 July 2024
exposure of different amounts of Bicoid, Nanos, and other morphogens. Those nuclei with more Bicoid will activate genes that promote differentiation of...
10 KB (1,175 words) - 23:27, 22 May 2024
FOX proteins (redirect from FOX gene)
transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity....
8 KB (874 words) - 23:04, 18 August 2023
Zerknüllt (category Gene stubs)
duplicated to give zen, zen2 and the even more divergent Bicoid gene. Large expansions of zen through gene duplication have also been observed within Lepidoptera...
6 KB (680 words) - 11:11, 17 October 2022
PROX1 (redirect from PROX1 (gene))
homeobox protein 1 is a protein that in humans is encoded by the PROX1 gene. The Prox1 gene is critical for the development of multiple tissues. Prox1 activity...
11 KB (1,103 words) - 22:24, 27 March 2024
Peter Lawrence. Christiane Nüsslein-Volhard identified the first morphogen, Bicoid, one of the transcription factors present in a gradient in the Drosophila...
8 KB (864 words) - 04:16, 29 July 2024
Peroxisome proliferator-activated receptor alpha (redirect from PPARA (gene))
functioning as a transcription factor that in humans is encoded by the PPARA gene. Together with peroxisome proliferator-activated receptor delta and peroxisome...
22 KB (2,563 words) - 18:52, 10 July 2024
Zbtb7 (redirect from Pokemon Gene)
is a gene that functions as a regulator of cellular growth and a proto oncogene. Zbtb7 is a member of the POK (POZ and Krüppel) family of genes, and the...
11 KB (1,301 words) - 14:54, 4 April 2024
KMT2A (redirect from MLL (gene))
in humans is encoded by the KMT2A gene. MLL1 is a histone methyltransferase deemed a positive global regulator of gene transcription. This protein belongs...
20 KB (2,275 words) - 19:46, 29 June 2024
GATA3 (redirect from GATA3 (gene))
GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes. The...
31 KB (3,723 words) - 06:25, 25 July 2024
KLF15 (redirect from KLF15 (gene))
Krüppel-like factor 15 is a protein that in humans is encoded by the KLF15 gene in the Krüppel-like factor family. Its former designation KKLF stands for...
21 KB (2,804 words) - 04:27, 26 February 2024
FOXP2 (redirect from FOX2P gene)
is encoded by the FOXP2 gene. FOXP2 is a member of the forkhead box family of transcription factors, proteins that regulate gene expression by binding to...
53 KB (5,880 words) - 06:15, 10 July 2024
Steroidogenic factor 1 (redirect from NR5A1 (gene))
controlling the activity of genes related to the reproductive glands or gonads and adrenal glands. This protein is encoded by the NR5A1 gene, a member of the nuclear...
29 KB (3,478 words) - 23:06, 27 March 2024
Maternal effect (section Paternal effect genes)
including bicoid, dorsal, gurken and oskar. For example, embryos from homozygous bicoid mothers fail to produce head and thorax structures. Once the gene that...
55 KB (7,202 words) - 06:01, 16 May 2024
NFE2L2 (redirect from NFE2L2 (gene))
2-like 2, is a transcription factor that in humans is encoded by the NFE2L2 gene. NRF2 is a basic leucine zipper (bZIP) protein that may regulate the expression...
29 KB (3,402 words) - 07:08, 20 May 2024