CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage...
8 KB (889 words) - 07:12, 15 October 2024
diagnosed CD33-positive acute myeloid leukemia (AML) for adults and children one month and older and for the treatment of relapsed or refractory CD33-positive...
17 KB (1,318 words) - 04:34, 1 October 2024
expression of CD33 in microglial cells in AD brain and showed that a protective CD33 gene variant was associated with reductions in CD33 expression and...
36 KB (4,371 words) - 06:48, 6 April 2024
SIGLEC8 (section CD33-related siglec subfamily)
Siglec-8 belongs to the CD33-related siglec subfamily, a subfamily that has undergone rapid evolution. Siglec-8 was first identified by CD33 homology screening...
35 KB (4,511 words) - 02:28, 28 March 2024
working for Lederle Labs. It is extremely toxic to all cells and, in 2000, a CD33 antigen-targeted immunoconjugate N-acetyl dimethyl hydrazide calicheamicin...
16 KB (1,506 words) - 18:06, 10 February 2024
Laboratories, now part of Pfizer). The drug is a recombinant, humanized anti-CD33 monoclonal antibody (IgG4 κ antibody hP67.6) covalently attached to the cytotoxic...
36 KB (3,957 words) - 06:55, 29 October 2024
Vadastuximab talirine is an antibody-drug conjugate (ADC) directed to CD33 (siglec-3) which is a transmembrane receptor expressed on cells of myeloid lineage...
7 KB (662 words) - 01:47, 30 May 2023
of complement. They express LCAs (leucocyte common antigens) CD45, CD14, CD33, and CD4 (also expressed by T helper cells). These histiocytes are part of...
6 KB (609 words) - 12:00, 10 August 2024
technology, melanoma (with MCSP specific BiTEs) and acute myeloid leukemia (with CD33 specific BiTEs) can be targeted. As of 2008[update], research in this area...
12 KB (1,727 words) - 23:52, 30 October 2024
Antibodies CD71/Transferrin receptor-1 CD13 marker for kidney disorder CD33 marker for AML treatment CD4+/CD8+ ratio Immune system Immune tolerance Leukocytes...
14 KB (1,368 words) - 17:53, 4 September 2024
subsets of human immune cells. Several other CD molecules, such as CD11b and CD33, are traditionally used as markers for human myeloid-derived suppressor cells...
17 KB (1,844 words) - 08:01, 29 April 2024
be negative. Immunophenotypically, M5-AML variably express myeloid (CD13, CD33) and monocytic (CD11b, CD11c) markers. Cells may aberrantly express B-cell...
6 KB (605 words) - 20:46, 23 July 2024
CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46...
11 KB (1,335 words) - 22:36, 11 October 2024
believe-in-luck;jsessionid=A8C0B1B63F4EF2D7DC45F27F4E723692?ctx=ef8e18aa-cd33-4c08-bfea-8a80df18bdbb&idx=3 Thomas Mann, "Memory Map" Collage Box with Brooch...
3 KB (341 words) - 04:16, 14 July 2023
AMIGO2 AXL BCAM BOC BSG BTLA C10orf72 C20orf102 CADM1 CADM3 CD200 CD22 CD276 CD33 CD4 CDON CEACAM1 CEACAM16 CEACAM20 CEACAM21 CEACAM5 CEACAM6 CEACAM8 CHL1...
6 KB (493 words) - 18:09, 13 July 2024
gemtuzumab relapsed acute myeloid leukemia targets myeloid cell surface antigen CD33 on leukemia cells humanized alemtuzumab B cell leukemia targets an antigen...
48 KB (4,964 words) - 04:26, 20 October 2024
CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46...
7 KB (757 words) - 08:44, 5 May 2024
Kodak EasyShare (redirect from Kodak Easyshare CD33)
Kodak EasyShare was a sub-brand of Eastman Kodak Company products identifying a consumer photography system of digital cameras, snapshot thermal printers...
14 KB (1,387 words) - 11:03, 10 October 2024
1999 CC33 — February 10, 1999 Socorro LINEAR · 2.2 km MPC · JPL 33381 1999 CD33 — February 10, 1999 Socorro LINEAR · 2.8 km MPC · JPL 33382 Indranidas 1999...
189 KB (301 words) - 02:18, 30 April 2024
cloning of Sialoadhesin by Crocker revealed homology to CD22 (Siglec-2), CD33 (Siglec-3) and myelin-associated glycoprotein (MAG/Siglec-4), leading to...
35 KB (3,968 words) - 06:48, 16 September 2024
Name Cytogenetics Percentage of adults with AML Immunophenotype CD14 CD15 CD33 HLA-DR Other M0 acute myeloblastic leukemia, minimally differentiated 5%...
75 KB (7,543 words) - 03:11, 2 November 2024
CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46...
45 KB (5,140 words) - 15:40, 24 October 2024
biopsies. The phenotypical characteristics of CMML are; CD11b, CD11c, CD14, CD33, CD45 and CD64 seen in 100% of cases; CD13 found in 95% of cases; CD4 found...
25 KB (2,922 words) - 14:19, 29 August 2023
CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46...
39 KB (4,995 words) - 13:28, 2 November 2024
CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46...
33 KB (3,930 words) - 21:04, 3 September 2024
myeloid dendritic cells, myeloid antigens like CD11b, CD11c, CD13, CD14 and CD33 are not present on pDC surfaces. Furthermore, pDCs express markers CD123...
14 KB (1,833 words) - 05:36, 27 December 2023
CD37 for Non-Hodgkin lymphoma (NHL). IMGN289, targeting EGFR IMGN779, a CD33-Targeted Antibody-Drug Conjugate (ADC) with a new DNA-Alkylating agent acts...
9 KB (803 words) - 02:06, 20 September 2024
— January 19, 2004 Kitt Peak Spacewatch · 2.4 km MPC · JPL 624796 2004 CD33 — January 28, 2004 Kitt Peak Spacewatch · 1.1 km MPC · JPL 624797 2004 CQ47...
187 KB (662 words) - 15:22, 10 October 2024
Nowadays, immunohistochemical staining using monoclonal antibodies against CD33 and CD117 would be the mainstay of diagnosis. The increasingly refined use...
16 KB (1,927 words) - 07:16, 5 November 2023
Rituximab Tositumomab), CD30 (Brentuximab), CD52 (Alemtuzumab) myeloid: CD33 (Gemtuzumab ozogamicin) Other Amivantamab Atezolizumab (+hyaluronidase) Avelumab...
12 KB (821 words) - 02:57, 12 October 2024